http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. More than 50,000 stem cell transplants are performed each year worldwide. A research team led by Weill Cornell Medical College investigators may have solved a major issue of expanding adult hematopoietic stem cells (HSCs) outside the human body for clinical use in bone marrow transplantation—a critical step towards producing a large supply of blood stem cells needed to restore a healthy blood system. http://medicalxpress.com/news/2013-03-method-blood-stem-cells-bone.html Medical research Thu, 21 Mar 2013 14:42:26 EST news283095727 As blood stem cells age, changes in the epigenome—the system that regulates which genes are switched on and which are switched off throughout the body—alter these cells in ways that lead to reduced immune response, increased anemia and rising risk of certain leukemias, researchers have found. http://medicalxpress.com/news/2013-02-ills-aging-blood-short-circuited-stem.html Medical research Fri, 15 Feb 2013 09:50:05 EST news280143511 Researchers have discovered an immune system 'kill switch' that destroys blood stem cells when the body is under severe stress, such as that induced by chemotherapy and systemic infections. http://medicalxpress.com/news/2012-12-immune-chemotherapy-infection-recovery.html Immunology Thu, 06 Dec 2012 12:00:37 EST news274005038 Canadian and Italian stem cell researchers have discovered a new "master control gene" for human blood stem cells and found that manipulating its levels could potentially create a way to expand these cells for clinical use. http://medicalxpress.com/news/2012-11-stem-cell-scientists-potential-cells.html Medical research Thu, 08 Nov 2012 14:47:27 EST news271608364 The protein GATA2 is known as a "master regulator" of blood cell development. When a mutation occurs in the gene that makes GATA2, serious blood diseases such as acute myeloid leukemia can result. http://medicalxpress.com/news/2012-09-genetic-mechanism-blood-cell-vessel.html Genetics Mon, 10 Sep 2012 12:00:19 EST news266491051 (HealthDay) -- As many as 300,000 people in the United States may have chronic Chagas disease -- mostly spread by blood-sucking insects -- health officials report. http://medicalxpress.com/news/2012-07-people-chagas-disease.html Diseases, Conditions, Syndromes Thu, 05 Jul 2012 17:20:01 EST news260725866 A team of international scientists led by principal investigator Dr. Tak Mak at the Princess Margaret Cancer Centre, University Health Network, has identified a causative link between the product of a mutated metabolic enzyme and the onset of acute myeloid leukemia (AML), one of the most common types of leukemia in adults. http://medicalxpress.com/news/2012-07-scientists-link-oncometabolite-onset-acute.html Cancer Wed, 04 Jul 2012 13:09:40 EST news260626161 (HealthDay) -- Despite scary headlines by the score, most people don't have to fear that they'll be the next victim of the so-called flesh-eating bacteria disease, experts say. http://medicalxpress.com/news/2012-05-flesh-eating-bacteria-panic-experts.html Diseases, Conditions, Syndromes Fri, 25 May 2012 14:30:16 EST news257167140 Walter and Eliza Hall Institute scientists have revealed new details about how cell signalling is controlled in the immune system, identifying in the process potential new therapeutic targets for treating severe blood disorders. http://medicalxpress.com/news/2012-02-cell-discovery-blood-disorders.html Medical research Thu, 16 Feb 2012 12:00:19 EST news248613349 A study of the cells that respond to crises in the blood system has yielded a few surprises, redrawing the 'map' of how blood cells are made in the body. http://medicalxpress.com/news/2012-01-redraws-blood-cell-production.html Medical research Tue, 31 Jan 2012 10:14:34 EST news247227263 (Medical Xpress) -- For the first time since stem cells were discovered by University of Toronto researchers 50 years ago, scientists have isolated a human blood stem cell in its purest form -- as a single stem cell capable of regenerating the entire blood system. This breakthrough opens the door to harnessing the power of these life-producing cells to treat cancer and other debilitating diseases more effectively. http://medicalxpress.com/news/2011-08-breakthrough-isolates-human-blood-stem.html Medical research Mon, 29 Aug 2011 05:18:17 EST news233813863