http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Cancer treatment is one of the most important areas of research in the medical world today. With research predominately conducted in large pharmaceutical research organisations, it is rather significant to hear of small medium enterprises (SMEs) developing their own innovative treatment for cancer. http://medicalxpress.com/news/2013-05-smes-presence-medical-world-cancer.html Cancer Tue, 14 May 2013 07:20:01 EST news287731970 (Medical Xpress)—Patients with advanced alveolar soft part sarcoma (ASPS), a rare cancer, achieved some control of their disease using an experimental anti-cancer drug called cediranib. The results from this largest clinical trial on ASPS to date were published online ahead of print on April 29, 2013, in the Journal of Clinical Oncology. The phase II trial was funded by the National Cancer Institute (NCI), part of the National Institutes of Health. http://medicalxpress.com/news/2013-05-experimental-drug-beneficial-nih-trial.html Cancer Tue, 07 May 2013 17:20:01 EST news287165013 Scientific collaborators from Yale School of Medicine and University College London (UCL) have uncovered the molecular pathway by which new arteries may form after heart attacks, strokes and other acute illnesses bypassing arteries that are blocked. Their study appears in the April 29 issue of Developmental Cell. http://medicalxpress.com/news/2013-04-arteries-bypassing-blocked.html Medical research Mon, 29 Apr 2013 12:00:01 EST news286452715 The retina is a highly vascularized tissue, but too much or too little vascularization can lead to visual impairment and diseases such as familial exudative vitreoretinopathy or macular degeneration. In this issue of the Journal of Clinical Investigation, Alfred Nordheim and colleagues at Tuebingen University in Tuebingen, Germany, identified the DNA transcription factor SRF and its cofactors MRTF-A and MRTF-B as critical regulators of vascularization in the postnatal mouse eye. http://medicalxpress.com/news/2013-04-transcription-factors-retinal-vascularization.html Medical research Mon, 08 Apr 2013 12:00:04 EST news284639184 The t haplotype in mice—a block of linked genes occupying the proximal half of mouse chromosome 17—is one of the best-studied examples of a selfish genetic element. Through an elaborate sperm-poisoning system, heterozygous males with only one copy of the t haplotype transfer the genetic element to over 95% of their progeny, while offspring that inherit two copies of the haplotype typically die during development. http://medicalxpress.com/news/2013-03-secrets-t-haplotype-gene-revealed-decade-long.html Genetics Fri, 08 Mar 2013 09:10:01 EST news281953820 Researchers at Wake Forest Baptist Medical Center and colleagues have identified a special population of adult stem cells in bone marrow that have the natural ability to migrate to the intestine and produce intestinal cells, suggesting their potential to restore healthy tissue in patients with inflammatory bowel disease (IBD). http://medicalxpress.com/news/2013-02-cell-therapy-bowel-disease.html Medical research Thu, 28 Feb 2013 04:14:29 EST news281247258 Scientists at the Stanford University School of Medicine have identified a set of proteins circulating in blood whose levels accurately flag the presence of lymphedema. The findings, to be reported Dec. 18 in PLoS ONE, spur optimism that this common but relatively neglected condition, which affects an estimated 10 million people in the United States, finally will be amenable to detection (and, eventually, treatment) with 21st-century techniques. http://medicalxpress.com/news/2012-12-blood-accurately-lymphedema.html Inflammatory disorders Tue, 18 Dec 2012 17:00:05 EST news275072203 A drug commonly used in treating breast cancer could have far wider benefits, offering a new way of preventing cancers spreading through the body, according to a University of Leeds-led study. http://medicalxpress.com/news/2012-11-breast-cancer-geldanamycin-drug-halt.html Cancer Tue, 06 Nov 2012 17:00:25 EST news271437943 With a worldwide shortage of kidneys for patients who need kidney transplants, researchers are diligently working to find ways to engineer new kidney tissue from a patient's own cells or another source. They've come a step closer to realizing that goal with a breakthrough described in an upcoming Journal of the American Society of Nephrology (JASN) study. The advance could lead to more options for individuals with kidney failure, as well as better tools for understanding kidney diseases and how to treat them. http://medicalxpress.com/news/2012-10-tissue-engineered-kidneys.html Other Thu, 18 Oct 2012 17:00:04 EST news269791126 The advanced neovascular, or "wet," form of age-related macular degeneration (AMD), left untreated, is the most common cause of vision loss among the elderly and a leading reason for their loss of driving privileges. But results of a new study, published in the online version of the journal Ophthalmology, suggest that monthly injections of ranibizumab improve eye chart test results required for a driver's license, build driver confidence and keep those with AMD driving longer. http://medicalxpress.com/news/2012-10-treatments-amd-elderly-drivers-wheel.html Ophthalmology Tue, 02 Oct 2012 12:24:40 EST news268399475 New research shows that a special population of stem cells found in cord blood has the innate ability to migrate to the intestine and contribute to the cell population there, suggesting the cells' potential to treat inflammatory bowel disease (IBD). http://medicalxpress.com/news/2012-09-cell-therapy-bowel-disease.html Diseases, Conditions, Syndromes Wed, 19 Sep 2012 15:53:24 EST news267288796 An inexpensive antifungal drug, thiabendazole, slows tumor growth and shows promise as a chemotherapy for cancer. Scientists in the College of Natural Sciences at The University of Texas at Austin made this discovery by exploiting the evolutionary relatedness of yeast, frogs, mice and humans. http://medicalxpress.com/news/2012-08-common-antifungal-drug-decreases-tumor.html Cancer Tue, 21 Aug 2012 03:03:57 EST news264737025 Magnetic resonance imaging (MRI) provides an indication of a breast tumor's response to pre-surgical chemotherapy significantly earlier than possible through clinical examination, according to a new study published online in the journal Radiology. http://medicalxpress.com/news/2012-05-breast-mri-chemotherapy-effectiveness.html Cancer Wed, 23 May 2012 04:40:02 EST news256966083 Researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have discovered a previously unknown mechanism which helps intestinal bacteria to affect the formation of blood vessels. The results, which are presented in Nature, may provide future treatments of intestinal diseases and obesity. http://medicalxpress.com/news/2012-03-body-bacteria-affect-intestinal-blood.html Medical research Mon, 26 Mar 2012 09:32:41 EST news251973147 BOSTON--Scientists at Dana-Farber Cancer Institute have identified a subtype of ovarian cancer able to build its own blood vessels, suggesting that such tumors might be especially susceptible to "anti-angiogenic" drugs that block blood vessel formation. http://medicalxpress.com/news/2012-02-subtype-ovarian-cancer-vulnerable-anti-angiogenic.html Cancer Tue, 14 Feb 2012 14:24:43 EST news248451869 Two recent studies by Van Andel Research Institute scientists are providing a foundation for a more complete understanding of distinct kidney cancer subtypes, which could pave the way for better treatments. http://medicalxpress.com/news/2011-12-picture-kidney-cancer.html Cancer Thu, 29 Dec 2011 16:14:29 EST news244397657 Scientists at the University of North Carolina at Chapel Hill School of Medicine have identified a cellular protein that plays a central role in the formation of new blood vessels. The molecule is the protein Shc (pronounced SHIK), and new blood vessel formation, or angiogenesis, is seriously impaired without it. http://medicalxpress.com/news/2011-11-cell-molecule-central-player-formation.html Medical research Mon, 28 Nov 2011 13:53:25 EST news241710764 In the first study using magnetic resonance imaging (MRI) to evaluate cardiovascular risk in World Trade Center (WTC) first responders, researchers from Mount Sinai School of Medicine have found that the responders who experienced high levels of exposure to the initial dust cloud on September 11, 2001, demonstrate high-risk features of atherosclerosis (plaque in arteries). The data was presented at the American Heart Association's Scientific Sessions 2011 in Orlando, Florida. http://medicalxpress.com/news/2011-11-wtc-workers-exposed-earlier-cloud.html Cardiology Wed, 16 Nov 2011 10:40:29 EST news240662413 Researchers have created a new phenotypic screening platform that better predicts success of drugs developed to prevent blood vessel tumor growth when moving out of the lab and onto actual tumors. http://medicalxpress.com/news/2011-11-effective-potential-cancer-drugs.html Cancer Sun, 13 Nov 2011 14:16:35 EST news240416187 Combining the investigational agents REGN910 and aflibercept yielded statistically significant improvements in antitumor effects in animal models compared with either agent alone, according to results presented at the AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics, held Nov. 12-16, 2011. http://medicalxpress.com/news/2011-11-combination-therapy-potent-tumor-growth.html Cancer Sun, 13 Nov 2011 14:14:57 EST news240416091 Skin squamous cell carcinomas are amongst the most frequent cancers in humans. Recent studies suggest that skin squamous cell carcinoma, like many other human cancers, contain particular cancer cells, known as cancer stem cells, that present increased self-renewal potential that sustain tumor growth. Little is known about the mechanisms that regulate cancer stem cell functions. http://medicalxpress.com/news/2011-10-role-vascular-endothelial-growth-factor.html Cancer Wed, 19 Oct 2011 13:00:01 EST news238247657 Cancer researchers are a step closer to finding a cure for advanced prostate cancer after effectively combining an anti-cancer drug with a viral gene therapy in vivo using novel ultrasound-targeted microbubble-destruction (UTMD) technology. The research was conducted by scientists at Virginia Commonwealth University Massey Cancer Center, VCU Institute of Molecular Medicine and School of Medicine, in collaboration with colleagues from Washington University School of Medicine and Sanford-Burnham Medical Research Institute. http://medicalxpress.com/news/2011-05-microbubble-delivered-combination-therapy-eradicates-prostate.html Cancer Tue, 10 May 2011 16:10:01 EST news224259908