http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Primary effusion lymphoma (PEL) is a rare, fatal form of aggressive B-cell lymphoma caused by Kaposi's sarcoma-associated herpesvirus (KSHV). The disease most commonly occurs in immunocompromised patients, such as those with HIV and the elderly. Because current treatment options are not effective, there is a great need for new PEL therapies. http://medicalxpress.com/news/2013-05-therapeutic-synergy-primary-effusion-lymphoma.html Cancer Wed, 01 May 2013 12:00:05 EST news286624931 Among patients with painful chemotherapy-induced peripheral neuropathy, use of the anti-depressant drug duloxetine for 5 weeks resulted in a greater reduction in pain compared with placebo, according to a study in the April 3 issue of JAMA. http://medicalxpress.com/news/2013-04-medication-duloxetine-pain-chemotherapy.html Cancer Tue, 02 Apr 2013 16:00:05 EST news284130084 Researchers at Mayo Clinic Cancer Center have developed new guidelines to treat recently diagnosed multiple myeloma patients who are not participating in clinical trials. The guidelines give physicians practical, easy to follow recommendations for providing initial therapy, stem cell transplant and maintenance therapy. The guidelines are published in the current issue of the journal Mayo Clinic Proceedings and represent a consensus opinion of hematologists at Mayo Clinic Cancer Center sites in Minnesota, Florida and Arizona. http://medicalxpress.com/news/2013-04-multiple-myeloma-treatment-guidelines-personalize.html Cancer Mon, 01 Apr 2013 12:23:08 EST news284037777 Chemists at the University of California, Riverside have developed a compound that holds much promise in the laboratory in fighting renal (kidney) cancer. http://medicalxpress.com/news/2013-02-compound-high-kidney-cancer.html Cancer Tue, 19 Feb 2013 16:16:17 EST news280512956 Researchers at Mayo Clinic in Florida have identified a new target to improve treatment of pancreatic ductal adenocarcinoma cancer, which accounts for more than 95 percent of pancreatic cancer cases. This fast-growing, often lethal cancer is resistant to conventional chemotherapy. The findings are published in the Jan. 3 online issue of PLOS ONE. http://medicalxpress.com/news/2013-01-scientists-molecule-pancreatic-cancer-treatment.html Cancer Thu, 03 Jan 2013 17:00:01 EST news276433930 (Medical Xpress)—Research from Karolinska Institutet shows that sorafenib, a drug used for advanced cancer of the kidneys and liver, could also be effective against multiple myeloma. The disease is one of the more common forms of blood cancer and is generally incurable. http://medicalxpress.com/news/2012-09-therapy-treatment-myeloma.html Cancer Wed, 05 Sep 2012 07:26:31 EST news266048780 (HealthDay) -- Patients with hematologic malignancies undergoing an HLA-mismatched unrelated donor (MMUD) reduced-intensity conditioning (RIC) hematopoietic stem cell transplantation (HSCT) may benefit from a prophylactic, short-course, bortezomib-based regimen to reduce the incidence of graft-versus-host disease (GVHD), according to research published online Aug. 6 in the Journal of Clinical Oncology. http://medicalxpress.com/news/2012-08-bortezomib-beneficial-graft-versus-host-disease-prophylaxis.html Cancer Wed, 08 Aug 2012 13:40:04 EST news263651987 (HealthDay) -- For patients with newly diagnosed multiple myeloma (MM), induction treatment with a combination of bortezomib, doxorubicin, and dexamethasone (PAD) followed by bortezomib maintenance therapy improves complete response (CR), progression-free survival (PFS), and overall survival (OS) rates, according to a study published online July 16 in the Journal of Clinical Oncology. http://medicalxpress.com/news/2012-07-bortezomib-ups-response-survival-multiple.html Cancer Mon, 23 Jul 2012 19:40:01 EST news262286111 (HealthDay) -- Kyprolis (carfilzomib) has been approved by the U.S. Food and Drug Administration to treat certain people with multiple myeloma who have already been given at least two prior therapies. http://medicalxpress.com/news/2012-07-kyprolis-multiple-myeloma.html Cancer Fri, 20 Jul 2012 15:13:08 EST news262015981 Two studies published today in Blood, the Journal of the American Society of Hematology (ASH), demonstrate preliminary success of an effective multiple myeloma (MM) regimen in patients with AL amyloidosis, a rare and devastating blood disease that results in deposition of damaging abnormal protein in critical organs of the body, including the kidneys, heart, liver, and intestines, and shares some characteristics with MM. http://medicalxpress.com/news/2012-02-powerful-myeloma-treatment-regimen-al.html Cancer Mon, 13 Feb 2012 13:28:09 EST news248362040 A drug used to treat cancer may also be effective in diseases that cause scarring of the internal organs or skin, such as pulmonary fibrosis or scleroderma. http://medicalxpress.com/news/2011-09-cancer-drug-scleroderma.html Medications Thu, 22 Sep 2011 17:02:40 EST news235929746 Clinical researchers at VCU Massey Cancer Center have successfully completed a Phase I clinical trial evaluating a combination of the drugs Bortezomib and Alvocidib in patients with relapsed or refractory blood cancers, paving the way for a Phase II clinical trial to test the safety and effectiveness of the new therapy. http://medicalxpress.com/news/2011-06-lab-clinic-therapy-blood-cancers.html Cancer Thu, 02 Jun 2011 17:24:01 EST news226254213