http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. (Medical Xpress)—Scientists at Washington University School of Medicine in St. Louis have helped identify many of the biomarkers for Alzheimer's disease that could potentially predict which patients will develop the disorder later in life. Now, studying spinal fluid samples and health data from 201 research participants at the Charles F. and Joanne Knight Alzheimer's Disease Research Center, the researchers have shown the markers are accurate predictors of Alzheimer's years before symptoms develop. http://medicalxpress.com/news/2013-05-alzheimer-markers-mental-decline.html Alzheimer's disease & dementia Tue, 14 May 2013 06:48:36 EST news287732906 Close family members of people with Alzheimer's disease are more than twice as likely as those without a family history to develop silent buildup of brain plaques associated with Alzheimer's disease, according to researchers at Duke Medicine. http://medicalxpress.com/news/2013-04-family-history-alzheimer-abnormal-brain.html Alzheimer's disease & dementia Wed, 17 Apr 2013 17:00:01 EST news285423778 Researchers at Washington University School of Medicine in St. Louis have identified a new set of genetic markers for Alzheimer's that point to a second pathway through which the disease develops. http://medicalxpress.com/news/2013-04-genetic-markers-id-alzheimer-pathway.html Alzheimer's disease & dementia Thu, 04 Apr 2013 12:32:42 EST news284297477 Sleep is disrupted in people who likely have early Alzheimer's disease but do not yet have the memory loss or other cognitive problems characteristic of full-blown disease, researchers at Washington University School of Medicine in St. Louis report March 11 in JAMA Neurology. http://medicalxpress.com/news/2013-03-loss-alzheimer-symptoms.html Alzheimer's disease & dementia Mon, 11 Mar 2013 16:00:03 EST news282221783 Only recently has it become possible to create high-quality images of the brain plaques characteristic of Alzheimer's disease in living people through positron emission tomography (PET). Even so, questions remain about what can be learned from these PET images and which people should have this test. http://medicalxpress.com/news/2013-01-guidelines-brain-amyloid-imaging-alzheimer.html Alzheimer's disease & dementia Mon, 28 Jan 2013 00:20:01 EST news278504680 Researchers at Washington University School of Medicine in St. Louis have found a key difference in the brains of people with Alzheimer's disease and those who are cognitively normal but still have brain plaques that characterize this type of dementia. http://medicalxpress.com/news/2012-10-clue-alzheimer-dementia-brain-samples.html Neuroscience Mon, 22 Oct 2012 12:43:48 EST news270128622 A new study shows that having a high amount of beta amyloid or "plaques" in the brain associated with Alzheimer's disease may cause steeper memory decline in mentally healthy older people than does having the APOE ɛ4 allele, also associated with the disease. The study is published in the October 16, 2012, print issue of Neurology, the medical journal of the American Academy of Neurology. http://medicalxpress.com/news/2012-10-plaque-build-up-brain-alzheimer-gene.html Neuroscience Mon, 15 Oct 2012 16:00:11 EST news269513181 Leading scientists have selected the first drugs to be evaluated in a worldwide clinical study to determine whether they can prevent Alzheimer's disease. http://medicalxpress.com/news/2012-10-drugs-chosen-major-alzheimer-trial.html Alzheimer's disease & dementia Wed, 10 Oct 2012 15:30:25 EST news269101818 Sleep disruptions may be among the earliest indicators of Alzheimer's disease, scientists at Washington University School of Medicine in St. Louis report Sept. 5 in Science Translational Medicine. http://medicalxpress.com/news/2012-09-problems-early-alzheimer.html Alzheimer's disease & dementia Wed, 05 Sep 2012 14:00:01 EST news266057923 A study, performed in mice and utilizing post-mortem samples of brains from patients with Alzheimer's disease, found that a single event of a moderate-to-severe traumatic brain injury (TBI) can disrupt proteins that regulate an enzyme associated with Alzheimer's. The paper, published in The Journal of Neuroscience, identifies the complex mechanisms that result in a rapid and robust post-injury elevation of the enzyme, BACE1, in the brain. These results may lead to the development of a drug treatment that targets this mechanism to slow the progression of Alzheimer's disease. http://medicalxpress.com/news/2012-07-brain-trauma-alzheimer-disease.html Alzheimer's disease & dementia Tue, 24 Jul 2012 17:10:09 EST news262368591 Scientists have assembled the most detailed chronology to date of the human brain's long, slow slide into full-blown Alzheimer's disease. http://medicalxpress.com/news/2012-07-timeline-brain-descent-alzheimer.html Alzheimer's disease & dementia Wed, 11 Jul 2012 17:00:06 EST news261242753 Greater purpose in life may help stave off the harmful effects of plaques and tangles associated with Alzheimer's disease, according to a new study by researchers at Rush University Medical Center. The study, published in the May issue of the Archives of General Psychiatry, is available online. http://medicalxpress.com/news/2012-05-purpose-life-brain-alzheimer-disease.html Alzheimer's disease & dementia Mon, 07 May 2012 16:00:22 EST news255611237 Scientist studying the way Alzheimer's takes root in the brain have identified important new similarities between a mouse model and human Alzheimer's. http://medicalxpress.com/news/2012-04-alzheimer-plaques-disrupt-brain-networks.html Alzheimer's disease & dementia Fri, 20 Apr 2012 10:27:27 EST news254136408 A marker for Alzheimer's disease rises and falls in the spinal fluid in a daily pattern that echoes the sleep cycle, researchers at Washington University School of Medicine in St. Louis have found. http://medicalxpress.com/news/2011-09-marker-alzheimer-disease-day-falls.html Alzheimer's disease & dementia Mon, 26 Sep 2011 16:22:03 EST news236272899 People with high cholesterol may have a higher risk of developing Alzheimer's disease, according to a study published in the September 13, 2011, issue of Neurology, the medical journal of the American Academy of Neurology. http://medicalxpress.com/news/2011-09-reveals-link-high-cholesterol-alzheimer.html Neuroscience Mon, 12 Sep 2011 16:00:26 EST news235043254 Picture yourself in Barbara Lesher's shoes: 54 years old and fearing you are developing Alzheimer's disease. http://medicalxpress.com/news/2011-07-alzheimer-debate.html Sleep apnea Thu, 21 Jul 2011 16:00:33 EST news230482805