http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. According to the American Cancer Society, nearly 40,000 women in the United States will succumb to breast cancer this year. Most of these women will die not from the primary tumor but rather tumor recurrence – the reappearance of the disease following treatment. http://medicalxpress.com/news/2013-06-protein-breast-cancer-recurrence-animal.html Cancer Thu, 13 Jun 2013 12:00:01 EST news290343094 Excess estrogen levels during pregnancy can disable, in their daughters, a powerful breast cancer tumor suppressor gene, say researchers at Georgetown Lombardi Comprehensive Cancer Center. They found the DNA repair gene BRCA1 to be silenced in one year-old girls exposed to a high hormonal fetal environment. http://medicalxpress.com/news/2013-04-excess-estrogen-pregnancy-silence-brca1.html Cancer Tue, 09 Apr 2013 13:00:02 EST news284730749 Patients with breast cancer who had a BRCA1 mutation had significantly worse overall and recurrence-free survival rates compared with patients without BRCA mutations, but no evidence for a difference in survival was found between patients with BRCA2 mutations and those without a BRCA mutation, according to data from a large Dutch study presented at the AACR Annual Meeting 2013, held in Washington, D.C., April 6-10. http://medicalxpress.com/news/2013-04-patients-brca1-mutations-brca2-poorer.html Cancer Tue, 09 Apr 2013 08:00:01 EST news284710874 Women with triple-negative breast cancer are more likely to have high levels of the MET biomarker in their tumours, making it a good new target for cancer drugs according to research published in the British Journal of Cancer, today (Wednesday). http://medicalxpress.com/news/2013-03-scientists-aggressive-breast-cancer.html Cancer Wed, 20 Mar 2013 06:30:01 EST news282977651 (Medical Xpress)—A new oral vaccine that produces a novel two-pronged immune system attack on cancer cells could be effective in preventing breast cancer recurrence, according to findings from a collaborative research team from the University of Cincinnati (UC) Cancer Institute and the National Institutes of Health (NIH). http://medicalxpress.com/news/2013-01-oral-breast-cancer-vaccine-tool.html Cancer Fri, 18 Jan 2013 08:06:27 EST news277718780 (HealthDay)—In women with breast cancer that has recurred but remains confined to in or near the breast, post-surgical chemotherapy appears to boost survival, new research shows. http://medicalxpress.com/news/2012-12-chemo-survival-breast-cancer.html Cancer Thu, 06 Dec 2012 16:20:01 EST news274030481 Researchers from The University of Texas MD Anderson Cancer Center found statins, the commonly used drug to lower cholesterol, improved progression-free survival in patients with inflammatory breast cancer (IBC). http://medicalxpress.com/news/2012-12-link-statins-survival-inflammatory-breast.html Cancer Thu, 06 Dec 2012 12:58:49 EST news274021119 (HealthDay)—For women with estrogen receptor (ER)-positive early breast cancer, continuing tamoxifen to 10 years correlates with reduced risk of recurrence and lower breast cancer-specific and overall mortality, according to a study published online Dec. 5 in The Lancet to coincide with presentation at the annual San Antonio Breast Cancer Symposium, held from Dec. 4 to 8. http://medicalxpress.com/news/2012-12-sabcs-tamoxifen-years-beneficial-breast.html Cancer Wed, 05 Dec 2012 16:00:01 EST news273944542 heralded for its low complication rates—actually results in more complications than whole-breast radiation one year after treatment, Yale School of Medicine researchers report in the October issue of the Journal of Clinical Oncology. http://medicalxpress.com/news/2012-10-older-breast-cancer-patients-complications.html Cancer Mon, 22 Oct 2012 16:00:04 EST news270136740 After surgeons removed the tumor from her breast last November, Karen Hajiaskari, of Hamburg, N.Y., was deemed cancer-free. But for the next five years she will take a drug called tamoxifen, a medication that's commonly used to prevent a breast cancer recurrence. http://medicalxpress.com/news/2012-10-additional-medicines-recurrence-issues.html Cancer Sun, 07 Oct 2012 15:30:01 EST news268839720 (Medical Xpress)—More than 40 percent of older breast cancer survivors are insufficiently active after leaving a supervised program. But new research shows that those women who developed behavioral skills such as self-confidence and motivation during their program were far more likely to continue exercising on their own. http://medicalxpress.com/news/2012-10-confidence-breast-cancer-survivors.html Cancer Thu, 04 Oct 2012 15:24:56 EST news268583071 Women treated for breast cancer after menopause with aromatase inhibitors have very high levels of sexual difficulties, including low interest, insufficient lubrication, and pain with intercourse. It is an important and underestimated problem, say the authors of a study published online in Menopause, the journal of the North American Menopause Society. http://medicalxpress.com/news/2012-09-breast-cancer-treatment-sexual-difficulties.html Cancer Mon, 24 Sep 2012 15:51:26 EST news267720671 A Rhode Island Hospital radiation oncologist says in a new editorial that research exploring the impact of radiotherapy in older women with low risk of breast cancer recurrence has little effect on actual clinical decisions. The editorial written by David E. Wazer, M.D., chief of the department of radiation oncology, is published in the current issue of the Journal of Clinical Oncology. http://medicalxpress.com/news/2012-08-older-women-benefit-radiotherapy-breast.html Cancer Tue, 21 Aug 2012 11:49:46 EST news264768580 (HealthDay) -- Pathologic complete response (pCR) is more highly predictive of recurrence-free survival (RFS) when specific breast cancer tumor type is factored in, according to a study published online May 29 in the Journal of Clinical Oncology. http://medicalxpress.com/news/2012-05-pathologic-response-survival-aided-tumor.html Cancer Wed, 30 May 2012 17:30:02 EST news257612096 "Cancer worry" is the fear that cancer will return, said researchers at Moffitt Cancer Center who studied cancer worry among breast cancer survivors and published their findings in Psycho-Oncology. They found that even three years after successful treatment, two-thirds of the 202 breast cancer survivors who participated in their study said they had "a moderate level of worry." http://medicalxpress.com/news/2012-04-breast-cancer-survivors.html Cancer Fri, 20 Apr 2012 11:20:01 EST news254136252 Caring for a wife with breast cancer can have a measurable negative effect on men's health, even years after the cancer diagnosis and completion of treatment, according to recent research. http://medicalxpress.com/news/2012-04-stress-wife-breast-cancer-health.html Health Mon, 16 Apr 2012 12:26:35 EST news253797988 A new blood test is twice as sensitive and can detect breast cancer recurrence a full year earlier than current blood tests, according to a scientist who reported here today at the 243rd National Meeting & Exposition of the American Chemical Society (ACS). http://medicalxpress.com/news/2012-03-more-sensitive-blood-recurring-breast-cancer.html Cancer Wed, 28 Mar 2012 16:30:01 EST news252151882 Detecting the presence of circulating tumour cells (CTCs) in the blood of women with early breast cancer after surgery but before the start of chemotherapy can provide useful information about their chances of surviving the disease. CTCs are cancer cells which are detectable in patients with a solid tumour and their value in the prognosis of metastatic breast cancer has been known for a few years. Until now, however, there has been little information about their role in early disease. http://medicalxpress.com/news/2012-03-cancer-cells-blood-chances-survival.html Cancer Thu, 22 Mar 2012 05:15:29 EST news251612123 Two studies published March 6 in the Journal of the National Cancer Institute provide insights about the CYP2D6 genotype in postmenopausal breast cancer patients and represent a major step forward in understanding the usefulness of CYP2D6 testing for deciding whether or not a patient should receive adjuvant tamoxifen for treatment of early-stage breast cancer. Both studies found that CYP2D6 genotypes that were indicative of reduced activity of enzymes that metabolize tamoxifen did not predict clinical responsiveness to adjuvant tamoxifen therapy among postmenopausal women with early-stage breast cancer. One study also found that CYP2D6 genotypes of reduced enzyme activity were not linked with fewer tamoxifen-induced hot flushes in patients. http://medicalxpress.com/news/2012-03-cyp2d6-genotype-tamoxifen-benefit.html Cancer Tue, 06 Mar 2012 16:00:07 EST news250263753 Researchers have linked increased starch intake to a greater risk for breast cancer recurrence, according to results presented at the 2011 CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 6-10, 2011. http://medicalxpress.com/news/2011-12-starch-intake-breast-cancer-recurrence.html Cancer Fri, 09 Dec 2011 02:40:35 EST news242620822 A second, larger clinical research study led by breast cancer specialists at Princess Margaret Hospital (PMH) has again proven that comparing a new biopsy of progressing or recurring cancer with that of the original cancer can dictate a change in treatment. http://medicalxpress.com/news/2011-11-biopsy-recurrent-breast-cancer-treatment.html Cancer Mon, 28 Nov 2011 16:00:08 EST news241715060 A new potential target to slow breast cancer tumor progression and metastasis has been identified by a team of researchers led by Dr. Richard Kremer from the Research Institute of the McGill University Health Centre (RI-MUHC). Complications in breast cancer patients are commonly caused by the spread of the disease through metastasis to other parts of the body, most often to the bones and lungs. These findings, published this week in the Journal of Clinical Investigation (JCI), suggest that a specific protein plays a key role in the progression of the disease outside of the initial tumor area. http://medicalxpress.com/news/2011-11-breast-cancer_1.html Cancer Thu, 10 Nov 2011 12:42:00 EST news240151312 A trial investigating the use of zoledronic acid to aid chemotherapy for breast cancer has found a significant benefit for post-menopausal women, according to results presented at the 2011 European Multidisciplinary Cancer Congress today. Researchers think it could be the key for a greater understanding of the mechanisms of breast cancer recurrence as well as offering new options for patient care. http://medicalxpress.com/news/2011-09-zoledronic-acid-recurrence-breast-cancer.html Cancer Sun, 25 Sep 2011 13:28:06 EST news236176073 The toxicities associated with aromatase inhibitors (AIs) may explain the lack of overall survival improvement compared with tamoxifen, according to a study published August 22 in the Journal of The National Cancer Institute. http://medicalxpress.com/news/2011-08-toxicity-aromatase-inhibitors-lack-survival.html Cancer Mon, 22 Aug 2011 16:26:47 EST news233249178 Two multi-gene tests designed to predict the risk of disease progression and response to chemotherapy in breast cancer produce broadly similar results for high- and low-risk patients, but do not always agree in their predictions for those at intermediate risk, a new analysis shows. http://medicalxpress.com/news/2011-05-breast-cancer-multi-gene.html Cancer Thu, 05 May 2011 09:56:03 EST news223808141 ACE inhibitors, commonly used to control high blood pressure and heart failure in women, may be associated with an increased risk of recurrence in women who have had breast cancer, according to a study by researchers at UCLA's Jonsson Comprehensive Cancer Center. http://medicalxpress.com/news/2011-04-ace-inhibitors-recurrence-breast-cancer.html Cancer Wed, 20 Apr 2011 09:04:00 EST news222509025