http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Joslin scientists report significant findings about the location, genetic expression and function of human brown adipose tissue (BAT) and the generation of new BAT cells. These findings, which appear in the April 2013 issue of Nature Medicine, may contribute to further study of BAT's role in human metabolism and developing treatments that use BAT to promote weight loss. http://medicalxpress.com/news/2013-04-scientists-advance-human-brown-adipose.html Medical research Mon, 22 Apr 2013 17:35:47 EST news285870940 Joslin scientists have discovered a mechanism that regulates the production of brown fat, a type of fat which plays an important role in heat production and energy metabolism. The findings, which appear in the upcoming issue of Nature, may lead to new therapies that increase BAT formation to treat obesity. http://medicalxpress.com/news/2013-03-team-mechanism-production-energy-burning-brown.html Medical research Wed, 13 Mar 2013 14:00:04 EST news282396182 Joslin Diabetes Center scientists have demonstrated that brown adipose tissue (BAT) has beneficial effects on glucose tolerance, body weight and metabolism. The findings, which may lead to new treatments for diabetes, appear in the upcoming issue of the Journal of Clinical Investigation. http://medicalxpress.com/news/2012-12-brown-adipose-tissue-beneficial-metabolism.html Medical research Mon, 10 Dec 2012 12:00:01 EST news274359138 Approximately 68 percent of U.S. adults are overweight or obese, according to the National Cancer Institute, which puts them at greater risk for developing cancer, cardiovascular disease, diabetes and a host of other chronic illnesses. But an international team of scientists led by Virginia Commonwealth University Massey Cancer Center researcher Andrew Larner, M.D., Ph.D., has successfully reversed obesity in mice by manipulating the production of an enzyme known as tyrosine-protein kinase-2 (Tyk2). In their experiments, the scientists discovered that Tyk2 helps regulate obesity in mice and humans through the differentiation of a type of fat tissue known as brown adipose tissue (BAT). http://medicalxpress.com/news/2012-12-scientists-mechanism-obesity.html Medical research Wed, 05 Dec 2012 13:53:40 EST news273938011 Imagine eating all of the sugar and fat that you want without gaining a pound. Thanks to new research published in The FASEB Journal, the day may come when this is not too far from reality. That's because researchers from the United States and Europe have found that blocking one of three opioid receptors in your body could turn your penchant for sweets and fried treats into a weight loss strategy that actually works. By blocking the delta opioid receptor, or DOR, mice reduced their body weight despite being fed a diet high in fat and sugar. The scientists believe that the deletion of the DOR gene in mice stimulated the expression of other genes in brown adipose tissue that promoted thermogenesis. http://medicalxpress.com/news/2012-07-opioid-receptors-drug-obesity.html Overweight and Obesity Tue, 31 Jul 2012 10:50:33 EST news262950619 Scientists at The University of Nottingham believe they've found a way of fighting obesity — with a pioneering technique which uses thermal imaging. This heat-seeking technology is being used to trace our reserves of brown fat — the body's 'good fat' — which plays a key role in how quickly our body can burn calories as energy. http://medicalxpress.com/news/2012-07-obesity-thermal-imaging.html Pediatrics Wed, 18 Jul 2012 12:22:50 EST news261832926 Scientists have identified a protein which regulates the activation of brown fat in both the brain and the body's tissues. Their research, which was conducted in mice, was published today, Friday 11 May, in the journal Cell. http://medicalxpress.com/news/2012-05-scientists-protein-brown-fat-calories.html Medical research Thu, 10 May 2012 12:00:01 EST news255868823 In the United States, a baby is born with a facial cleft every hour, of every day of the year! Such birth defects result from both gene mutations and environmental insults. PRDM16 is a transcription factor originally described as being aberrantly activated in specific types of leukemia's, and more recently as a master regulator of brown adipose tissue differentiation. In a study published in the April 2012 issue of Experimental Biology and Medicine, investigators have now shown that this transcription co-factor plays a critical role in development of the embryonic palate. http://medicalxpress.com/news/2012-05-prdm16-gene-important-craniofacial.html Medical research Wed, 02 May 2012 11:27:03 EST news255176800 Brown adipose tissue (often known as brown fat) is a specialized tissue that burns calories to generate body heat in rodents and newborn humans, neither of which shiver. http://medicalxpress.com/news/2012-01-brown-fat-calories-adult-humans.html Medical research Tue, 24 Jan 2012 12:58:05 EST news246632273 (Medical Xpress) -- Researchers at Genetech Inc. in South San Francisco, California, led by molecular biologist Junichiro Sonoda, have discovered that a single injection of antibodies into obese diabetic mice provided a marked and sustained improvement in their condition and a reduction in their weight. http://medicalxpress.com/news/2011-12-antibody-diabetes-obesity.html Medical research Fri, 16 Dec 2011 06:00:01 EST news243233160 Activating a specialized type of fat, known as brown adipose tissue, may help combat obesity as well as result in better glucose control for type 2 diabetes, according to new research conducted by scientists at the UC Metabolic Diseases Institute. http://medicalxpress.com/news/2011-10-treatments-obesity-diabetes.html Diseases, Conditions, Syndromes Tue, 11 Oct 2011 08:17:09 EST news237539821