http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. A newly identified set of genes may predict which women are at high risk for getting breast cancer that is sensitive to estrogen and, therefore, would be helped by taking drugs to prevent it, reports a new Northwestern Medicine study. http://medicalxpress.com/news/2013-03-genes-breast-cancer-aid.html Cancer Tue, 19 Mar 2013 13:21:54 EST news282918105 A series of microRNA expression signatures that may help to define progression of the precancerous condition Barrett's esophagus into esophageal adenocarcinoma was reported recently in Cancer Prevention Research, a journal of the American Association for Cancer Research. http://medicalxpress.com/news/2013-03-biomarkers-barrett-esophagus-esophageal-adenocarcinoma.html Cancer Wed, 06 Mar 2013 00:20:01 EST news281724446 Visceral fat, or fat stored deep in the abdominal cavity, is directly linked to an increased risk for colon cancer, according to data from a mouse study published in Cancer Prevention Research, a journal of the American Association for Cancer Research. http://medicalxpress.com/news/2013-03-visceral-fat-causally-linked-intestinal.html Cancer Wed, 06 Mar 2013 00:10:02 EST news281724370 A Wayne State University researcher has identified characteristics in benign breast disease associated with future cancer risk in African-American women. http://medicalxpress.com/news/2013-02-cancer-african-american-women-benign-breast.html Cancer Mon, 11 Feb 2013 16:10:01 EST news279819694 A new multiple gene expression profile test was able to predict the presence of harmful BRCA1 or BRCA2 mutations in otherwise healthy women carrying the mutations, according to data published in Cancer Prevention Research, a journal of the American Association for Cancer Research. http://medicalxpress.com/news/2013-01-presence-brca-mutations.html Cancer Tue, 22 Jan 2013 13:00:01 EST news278073437 (Medical Xpress)—A high-fiber diet may have the clinical potential to control the progression of prostate cancer in patients diagnosed in early stages of the disease. http://medicalxpress.com/news/2013-01-high-fiber-diet-prostate-cancer.html Cancer Wed, 09 Jan 2013 16:04:17 EST news276969852 Testing medicines to prevent lung cancer requires treating many thousands of high-risk individuals and then waiting 5, 10 or 15 years to discover which of them develop cancer and which, if any, experience survival benefit from the treatment. A University of Colorado Cancer Center study recently published in the journal Cancer Prevention Research proposes a possible waypoint on the way to benefit, which if validated, could dramatically reduce the number of patients needed and time required to test drugs for lung cancer prevention. http://medicalxpress.com/news/2013-01-marker-drug-response-pace-lung.html Cancer Tue, 08 Jan 2013 14:35:32 EST news276878008 (Medical Xpress)—A first-of-its-kind vaccine developed by University of Pittsburgh Cancer Institute (UPCI) researchers successfully prompted the immune system to respond to early indications of colon cancer in people at high risk for the disease. http://medicalxpress.com/news/2013-01-vaccine-triggers-immunity-colon-cancer.html Cancer Tue, 08 Jan 2013 08:12:09 EST news276855120 Men with prostate cancer who consumed green tea prior to undergoing prostatectomy had reductions in markers of inflammation, according to data presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research, held here Oct. 16-19, 2012. http://medicalxpress.com/news/2012-10-green-tea-inflammation-inhibit-prostate.html Cancer Fri, 19 Oct 2012 07:50:01 EST news269850962 The compound licofelone inhibited oral cancer growth by inhibiting the cyclooxygenase and 5-lipoxygenase pathways, with no observable side effects, according to data from a rat study presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research, held here Oct. 16-19, 2012. http://medicalxpress.com/news/2012-10-compound-dual-action-inhibits-oral.html Cancer Fri, 19 Oct 2012 07:34:48 EST news269850881 An oral green tea extract, Polyphenon E, appears to inhibit vascular endothelial growth factor and hepatocyte growth factor, both of which promote tumor cell growth, migration and invasion. http://medicalxpress.com/news/2012-10-mechanisms-action-green-tea-breast.html Cancer Thu, 18 Oct 2012 15:00:17 EST news269786109 Increased concentrations of the pregnancy hormones estradiol and progesterone were associated with an increased risk for hormone receptor-negative breast cancer diagnosed before age 50, according to the results of a nested case-control study presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research, held here Oct. 16-19, 2012. http://medicalxpress.com/news/2012-10-high-hormones-pregnancy-higher-hr-negative.html Cancer Thu, 18 Oct 2012 15:00:06 EST news269786242 When smoking co-workers in the same team are placed on a cessation program, providing financial incentives to the team collectively in return for success of the smokers in the cessation program helped the smokers to quit smoking and remain abstinent for 12 months, according to data presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research, held Oct. 16-19, 2012. http://medicalxpress.com/news/2012-10-team-cessation-workplace-cigarette-smokers.html Health Thu, 18 Oct 2012 15:00:02 EST news269786311 Blood hormone tests can predict a woman's risk for developing postmenopausal breast cancer for up to 20 years, according to a study led by Xuehong Zhang, MD, Channing Division of Network Medicine, Brigham and Women's Hospital (BWH) Department of Medicine. http://medicalxpress.com/news/2012-10-blood-hormone-long-term-breast-cancer.html Cancer Thu, 18 Oct 2012 15:00:01 EST news269786031 Breast-feeding reduces the risk for estrogen receptor-negative and progesterone receptor-negative breast cancer, according to a study conducted at Columbia University's Mailman School of Public Health. Researchers examined the association between reproductive risk factors—such as the number of children a woman delivers, breast-feeding and oral contraceptive use – and found an increased risk for estrogen receptor- and progesterone receptor- (ER/PR) negative breast cancer in women who do not breast-feed. The results also indicated that having three or more children without breast-feeding was associated with an increased risk for ER/PR-negative breast cancer. ER/PR-negative breast cancer often affects younger women and has a poor prognosis. http://medicalxpress.com/news/2012-10-breastfeeding-erpr-negative-breast-cancer.html Cancer Thu, 18 Oct 2012 13:47:53 EST news269786864 Disease education about overlapping behavioral risk factors for both cancer and cardiovascular disease led to small changes in dietary behavior among a community-based sample of African-American adults, according to data presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research, held here Oct. 16-19, 2012. http://medicalxpress.com/news/2012-10-factors-cancer-cvd-fruit-consumption.html Health Thu, 18 Oct 2012 07:43:56 EST news269765019 Achieving and maintaining a healthy body weight, staying physically active and maintaining a healthy diet improved survival after cancer diagnosis in an elderly female cancer survivor population, according to data presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research, held here Oct. 16-19, 2012. http://medicalxpress.com/news/2012-10-adhering-lifestyle-guidelines-mortality-elderly.html Cancer Wed, 17 Oct 2012 15:01:39 EST news269704881 The combination of shortened telomeres, a biological marker of aging associated with cancer development, and elevated depression significantly impacted bladder cancer mortality, according to data presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research, held here Oct. 16-19, 2012. http://medicalxpress.com/news/2012-10-depression-shortened-telomeres-bladder-cancer.html Cancer Wed, 17 Oct 2012 15:00:06 EST news269704678 Twenty-nine percent of patients with colorectal cancer in a nationally representative sample were diagnosed after an emergency, such as an obstruction or perforation of the bowel, according to data presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research, held here Oct. 16-19, 2012. In addition, African-Americans and those living in high-poverty areas were more likely to present with an emergency diagnosis. http://medicalxpress.com/news/2012-10-socioeconomics-impact-emergency-colorectal-cancer.html Cancer Wed, 17 Oct 2012 15:00:04 EST news269704732 Two components of red meat—dietary protein and dietary iron—may combine to form powerful carcinogens, N-nitroso compounds, which increase risk for bladder cancer. Moreover, individuals with reduced ability to reverse the effects of N-nitroso compounds because of a genetic variation in their RAD52 gene could be at particularly high risk. http://medicalxpress.com/news/2012-10-components-red-meat-combined-dna.html Cancer Wed, 17 Oct 2012 15:00:03 EST news269704779 Nearly 38 percent of lesbians polled in a national survey were not routinely screened for cervical cancer, putting them at risk of developing a highly preventable cancer, according to a University of Maryland School of Medicine study being presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research. Cervical cancer is caused by a sexually transmitted virus, the human papillomavirus (HPV), and can be detected through regular Pap smears. http://medicalxpress.com/news/2012-10-lesbians-routinely-screened-cervical-cancer.html Cancer Wed, 17 Oct 2012 15:00:02 EST news269704216 Results of one study indicate that the risk for developing pediatric acute lymphoblastic leukemia increased the longer a baby was fed formula and the longer solid foods were delayed. http://medicalxpress.com/news/2012-10-prolonged-formula-solid-foods-pediatric.html Cancer Wed, 17 Oct 2012 10:37:26 EST news269689033 In a randomized trial that included nearly 15,000 male physicians, long-term daily multivitamin use resulted in a modest but statistically significant reduction in cancer after more than a decade of treatment and follow-up, according to a study appearing in JAMA. The study is being published early online to coincide with its presentation at the Annual American Association for Cancer Research Frontiers in Cancer Prevention Research meeting. http://medicalxpress.com/news/2012-10-daily-multivitamins-cancer-men.html Cancer Wed, 17 Oct 2012 10:35:09 EST news269688900 A new noninvasive test for colorectal cancer screening demonstrated high sensitivity for detecting colorectal cancer, in particular precancers that are most likely to develop into cancer, according to data presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research, held here Oct. 16-19, 2012. http://medicalxpress.com/news/2012-10-noninvasive-colorectal-cancer.html Cancer Tue, 16 Oct 2012 13:30:42 EST news269612998 A group of molecular markers have been identified that can help clinicians determine which patients with low-grade oral premalignant lesions are at high risk for progression to oral cancer, according to data from the Oral Cancer Prediction Longitudinal Study published in Cancer Prevention Research, a journal of the American Association for Cancer Research. http://medicalxpress.com/news/2012-08-markers-oral-lesions-cancer.html Cancer Tue, 21 Aug 2012 13:28:03 EST news264774416 In addition to the well-known risk factor of smoking, chronic obstructive pulmonary disease (COPD) increases lung cancer risk. http://medicalxpress.com/news/2012-07-chronic-obstructive-pulmonary-disease-lung.html Cancer Tue, 24 Jul 2012 15:25:25 EST news262362318 Next time you need to choose between vegetable oil and margarine in that favorite recipe, think about your health and reach for the oil. http://medicalxpress.com/news/2012-04-vitamin-diet-cancers-commonly-supplements.html Health Mon, 23 Apr 2012 11:48:34 EST news254400495 New findings published in Cancer Prevention Research, a journal of the American Association for Cancer Research, suggest that metformin may protect against oral cancer. http://medicalxpress.com/news/2012-04-metformin-oral-cancer.html Cancer Mon, 02 Apr 2012 06:16:17 EST news252566169 Metformin, a drug widely used to treat Type II diabetes, may help to prevent primary liver cancer, researchers at the University of Maryland Marlene and Stewart Greenebaum Cancer Center report in the April 2012 issue of Cancer Prevention Research. Primary liver cancer, or hepatocellular carcinoma, is an often-deadly form of cancer that is on the rise worldwide and is the fastest-growing cause of cancer-related deaths among American men. http://medicalxpress.com/news/2012-04-commonly-diabetes-drug-primary-liver.html Cancer Sun, 01 Apr 2012 06:14:05 EST news252479627 Cancer is usually attributed to faulty genes, but growing evidence from the field of cancer epigenetics indicates a key role for the gene "silencing" proteins that stably turn genes off inside the cell nucleus. A new study from Rice University and Baylor College of Medicine (BCM) promises to speed research in the field by rapidly identifying the genes that epigenetic proteins can target for silencing. http://medicalxpress.com/news/2012-03-cancer-epigenetics-breakthrough-iding-genes.html Cancer Tue, 13 Mar 2012 16:55:30 EST news250876524