http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. An experimental vaccine study currently under way at the UC Cancer Institute aims to prevent ovarian cancer recurrence by triggering the body’s natural defense system. http://medicalxpress.com/news/2012-03-experimental-vaccine-aimed-ovarian-cancer.html Cancer Fri, 02 Mar 2012 07:54:48 EST news249897281 New research takes aim at stubborn cancer stem cells that are thought to be responsible for treatment resistance and relapse. The study, published by Cell Press in the February 14 issue of the journal Cancer Cell, provides insight into mechanisms associated with the survival of leukemia stem cells and identifies a potential therapeutic target that is specific for these dangerously persistent cells. http://medicalxpress.com/news/2012-02-therapy-leukemia-stem-cells.html Cancer Mon, 13 Feb 2012 14:10:01 EST news248362666 A new study has found that many older lung cancer patients get treatments that may not help them live longer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings suggest that physicians should not routinely use radiation after surgery to treat lung cancer that is advanced but has not widely spread, at least in older patients. http://medicalxpress.com/news/2012-02-lung-cancer-patients-therapy-prolong.html Cancer Mon, 13 Feb 2012 03:20:03 EST news248325587 There is a need to analyze tumor specimens at the time of ovarian cancer recurrence, according to a new study published in Molecular Cancer Therapeutics. Researchers used a diagnostic technology called molecular profiling to examine the differences in the molecular characteristics of primary and recurrent ovarian tumors and found significant changes for some biomarkers. This is the first study that examined potential differences in a broad biomarker panel in patient-matched primary versus recurrent ovarian cancers and underscores the importance of analyzing the most current tumor tissue in order to make the most informed decisions about treatment for recurrence. http://medicalxpress.com/news/2012-02-molecular-profiling-reveals-differences-primary.html Cancer Fri, 10 Feb 2012 13:06:25 EST news248101576 Bladder cancer, most frequently caused by smoking and exposure to carcinogens in the workplace, is one of the top 10 most common forms of cancer in men and women in the U.S. More than 70 percent of bladder cancers are diagnosed in stage T1 or less and have not invaded the muscle layer. At these early stages, standard treatment is surgery (transurethral resection) and the burning away of tumors with high energy electricity (fulguration). Many patients also may receive subsequent intravesical chemotherapy because there is often a high-risk for cancer recurrence. http://medicalxpress.com/news/2012-01-body-defenses-cutting-edge-gene-therapy.html Cancer Tue, 10 Jan 2012 12:17:50 EST news245420266 Not only is overall quality of life higher in cancer survivors who exercise, but the rate of cancer recurrence is lower. Unfortunately, though most doctors recommend exercise, many patients fail to follow through. http://medicalxpress.com/news/2012-01-downloadable-tool-cancer-survivors.html Cancer Wed, 04 Jan 2012 15:56:13 EST news244914963 Obesity doubles the risk of cancer recurrence and cancer-related death in patients with esophageal cancer who have been treated with surgery, researchers at Mayo Clinic found. Their 778-patient study, which appeared in the Dec. 1 issue of the Journal of Clinical Oncology, found that five-year survival in obese patients -- those with a body mass index of 30 or higher -- with esophageal cancer was 18 percent, compared to 36 percent in patients of normal weight. http://medicalxpress.com/news/2011-12-obesity-linked-higher-year-death.html Surgery Tue, 20 Dec 2011 13:16:18 EST news243609347 A new treatment using leukemia patients' own infection-fighting cells appears to protect them from infections and cancer recurrence following treatment with fludarabine-based chemotherapy, according to new research from the Perelman School of Medicine at the University of Pennsylvania. The new process is a step toward eliminating the harsh side effects that result from the commonly prescribed drug, which improves progression-free survival in patients with chronic lymphocytic leukemia (CLL) but destroys patients' healthy immune cells in the process, leaving them vulnerable to serious viral and bacterial infections. The drug's effects on the immune system tend to be so violent that it has been dubbed "AIDS in a bottle." http://medicalxpress.com/news/2011-12-immune-leukemia-patients-chemotherapy.html Cancer Mon, 12 Dec 2011 03:59:37 EST news242884769 (AP) -- Doctors were mostly hoping to prevent complications and relapses when they gave young women a medicine to keep their bones strong during breast cancer treatment. Seven years later, they found it did more than that: The bone drug improved survival, as much as many chemotherapies do. http://medicalxpress.com/news/2011-12-bone-drug-boosts-breast-cancer.html Cancer Fri, 09 Dec 2011 03:10:01 EST news242621950 Researchers have linked increased starch intake to a greater risk for breast cancer recurrence, according to results presented at the 2011 CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 6-10, 2011. http://medicalxpress.com/news/2011-12-starch-intake-breast-cancer-recurrence.html Cancer Fri, 09 Dec 2011 02:40:35 EST news242620822 Accelerated partial breast irradiation (APBI) brachytherapy, the localized form of radiation therapy growing increasingly popular as a treatment choice for women with early-stage breast cancer, is associated with higher rate of later mastectomy, increased radiation-related toxicities and post-operative complications, compared to traditional whole breast irradiation (WBI), according to researchers from The University of Texas MD Anderson Cancer Center. http://medicalxpress.com/news/2011-12-side-effects-complications-mastectomy-partial.html Cancer Wed, 07 Dec 2011 05:00:01 EST news242454425 The American Society of Clinical Oncology (ASCO) today released Clinical Cancer Advances 2011: ASCO's Annual Report on Progress Against Cancer, an independent review of the advances in cancer research that have had the greatest impact on patient care this year. The report also identifies the most promising trends in oncology and provides insights from experts on where the future of cancer care is heading. http://medicalxpress.com/news/2011-12-american-society-clinical-oncology-issues.html Cancer Mon, 05 Dec 2011 16:36:10 EST news242325328 Lymphedema, a chronic swelling condition common in breast cancer survivors, affects three million people in the U.S. In the past, most people believed that exercise might induce or worsen lymphedema. After reviewing the literature, University of Missouri researchers say the benefits of exercise outweigh the risks for breast cancer survivors and patients with lymphedema. http://medicalxpress.com/news/2011-12-mu-breast-cancer-survivors-lymphedema.html Cancer Thu, 01 Dec 2011 12:20:05 EST news241963590 A second, larger clinical research study led by breast cancer specialists at Princess Margaret Hospital (PMH) has again proven that comparing a new biopsy of progressing or recurring cancer with that of the original cancer can dictate a change in treatment. http://medicalxpress.com/news/2011-11-biopsy-recurrent-breast-cancer-treatment.html Cancer Mon, 28 Nov 2011 16:00:08 EST news241715060 A new potential target to slow breast cancer tumor progression and metastasis has been identified by a team of researchers led by Dr. Richard Kremer from the Research Institute of the McGill University Health Centre (RI-MUHC). Complications in breast cancer patients are commonly caused by the spread of the disease through metastasis to other parts of the body, most often to the bones and lungs. These findings, published this week in the Journal of Clinical Investigation (JCI), suggest that a specific protein plays a key role in the progression of the disease outside of the initial tumor area. http://medicalxpress.com/news/2011-11-breast-cancer_1.html Cancer Thu, 10 Nov 2011 12:42:00 EST news240151312 (Medical Xpress) -- Radiotherapy following surgery for breast cancer halves the chances of the cancer coming back over the next 10 years, a study led by Oxford University researchers has found. http://medicalxpress.com/news/2011-10-radiotherapy-surgery-halves-breast-cancer.html Cancer Thu, 20 Oct 2011 08:29:32 EST news238318164 Patients with Merkel Cell Carcinoma who underwent a procedure called sentinel lymph node biopsy (SNLB) had a lower risk of cancer recurrence after two years, according to a study by researchers from Fox Chase Cancer Center. When the biopsy's results were used to guide subsequent tests and treatment, these patients had longer survival rates than patients who had not undergone the procedure. http://medicalxpress.com/news/2011-10-sentinel-lymph-node-biopsy-outcomes_1.html Cancer Mon, 03 Oct 2011 19:06:15 EST news236887470 A trial investigating the use of zoledronic acid to aid chemotherapy for breast cancer has found a significant benefit for post-menopausal women, according to results presented at the 2011 European Multidisciplinary Cancer Congress today. Researchers think it could be the key for a greater understanding of the mechanisms of breast cancer recurrence as well as offering new options for patient care. http://medicalxpress.com/news/2011-09-zoledronic-acid-recurrence-breast-cancer.html Cancer Sun, 25 Sep 2011 13:28:06 EST news236176073 Stockholm, Sweden: A major UK trial has produced firm evidence that giving radiotherapy between or during chemotherapy cycles to women with early breast cancer significantly reduces the risk of the cancer recurring in the breast or chest wall. The treatment, known as synchronous chemoradiation, has minimal adverse side-effects and no detrimental effect on the patients' quality of life. http://medicalxpress.com/news/2011-09-radiotherapy-chemotherapy-breast-cancer-recurrence.html Cancer Sun, 25 Sep 2011 04:10:31 EST news236142620 The toxicities associated with aromatase inhibitors (AIs) may explain the lack of overall survival improvement compared with tamoxifen, according to a study published August 22 in the Journal of The National Cancer Institute. http://medicalxpress.com/news/2011-08-toxicity-aromatase-inhibitors-lack-survival.html Cancer Mon, 22 Aug 2011 16:26:47 EST news233249178 Mayo Clinic has received investigational new drug approval from the Food and Drug Administration for two new cancer vaccines that mobilize the body's defense mechanisms to destroy malignant cells. The vaccines are among the first aimed at preventing cancer recurrence. The approval clears the way for Phase I clinical trials with women treated for ovarian or breast cancer. http://medicalxpress.com/news/2011-08-mayo-clinic-fda-ovarian-breast.html Cancer Wed, 17 Aug 2011 13:46:24 EST news232807571 (Medical Xpress) -- Can a gel applied to the skin of a woman's breast provide the same cancer-fighting benefits as a pill taken by mouth but reduce the side effects of the medicine? http://medicalxpress.com/news/2011-07-gel-cancer-tumors.html Cancer Fri, 08 Jul 2011 07:47:51 EST news229329999 Can a gel applied to the skin of a woman's breast provide the same cancer-fighting benefits as a pill taken by mouth but reduce the side effects of the medicine? http://medicalxpress.com/news/2011-06-topical-skin-gel-breast-cancer.html Cancer Fri, 24 Jun 2011 10:17:15 EST news228129398 A new study from Harvard School of Public Health (HSPH) and University of California, San Francisco, researchers suggests that men with prostate cancer who smoke increase their risk of prostate cancer recurrence and of dying from the disease. A link also was found between smoking at the time of prostate cancer diagnosis and aggressive prostate cancer, overall mortality (death) and cardiovascular disease mortality. http://medicalxpress.com/news/2011-06-prostate-cancer-recurrence-death.html Cancer Tue, 21 Jun 2011 16:26:17 EST news227892240 Using a combination of hypnosis and local anaesthesia (LA) for certain types of surgery can aid the healing process and reduce drug use and time spent in hospital, anaesthesiologists have found. The combination could also help avoid cancer recurrence and metastases, according to new research to be presented today (Sunday) at the European Anaesthesiology Congress in Amsterdam. http://medicalxpress.com/news/2011-06-hypnosislocal-anesthesia-combination-surgery-patients.html Other Sat, 11 Jun 2011 18:32:52 EST news227035948 Colorectal cancer patients with defects in mismatch repair--one of the body's systems for repairing DNA damage--have lower recurrence rates and better survival rates than patients without such defects, according to a study published online May 19th in the Journal of the National Cancer Institute. http://medicalxpress.com/news/2011-05-dna-affects-colon-cancer-recurrence.html Cancer Thu, 19 May 2011 16:23:38 EST news225040984 Researchers from Virginia Commonwealth University Massey Cancer Center have discovered a new biomarker related to the body's immune system that can predict a breast cancer patients' risk of cancer recurrence. This breakthrough may lead to new genetic testing that further personalizes breast cancer care. http://medicalxpress.com/news/2011-05-biomarker-breast-cancer-relapse.html Cancer Mon, 16 May 2011 12:43:11 EST news224768571 Two multi-gene tests designed to predict the risk of disease progression and response to chemotherapy in breast cancer produce broadly similar results for high- and low-risk patients, but do not always agree in their predictions for those at intermediate risk, a new analysis shows. http://medicalxpress.com/news/2011-05-breast-cancer-multi-gene.html Cancer Thu, 05 May 2011 09:56:03 EST news223808141 A pelvic MRI scan with IV contrast and rectal balloon is highly effective in identifying local recurrence even at low PSA values in prostate cancer patients with a rising or persistently elevated PSA after prostatectomy, according to a study presented April 29, 2011, at the Cancer Imaging and Radiation Therapy Symposium in Atlanta. The symposium is co-sponsored by the American Society for Radiation Oncology (ASTRO) and the Radiological Society of North America (RSNA). http://medicalxpress.com/news/2011-04-mri-prostate-cancer-recurrence-extremely.html Cancer Fri, 29 Apr 2011 08:23:21 EST news223284188 ACE inhibitors, commonly used to control high blood pressure and heart failure in women, may be associated with an increased risk of recurrence in women who have had breast cancer, according to a study by researchers at UCLA's Jonsson Comprehensive Cancer Center. http://medicalxpress.com/news/2011-04-ace-inhibitors-recurrence-breast-cancer.html Cancer Wed, 20 Apr 2011 09:04:00 EST news222509025