http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. (Medical Xpress)—The spread of cancer cells may be slowed by targeting the protein km23-1, according to researchers at Penn State College of Medicine. http://medicalxpress.com/news/2012-12-cancer-cells-protein.html Cancer Tue, 18 Dec 2012 10:38:08 EST news275049478 UC College of Engineering and Applied Science chemical and materials engineering associate professor, Chia-Chi Ho, announces ability to sort and steer cells, opening doors to a potential future of steering disease and cancer related cells into diagnostic and treatment solutions. http://medicalxpress.com/news/2012-12-closer-cell.html Medical research Tue, 11 Dec 2012 08:50:10 EST news274438179 Lung cancer researchers at St. Joseph's Hospital and Medical Center in Phoenix, Ariz., in collaboration with researchers at the Translational Genomics Research Institute and other institutions, have identified a gene that plays a role in the growth and spread of non-small cell lung cancer tumors, opening the door for potential new treatment options. http://medicalxpress.com/news/2012-11-gene-involved-lung-tumor-growth.html Cancer Thu, 29 Nov 2012 16:43:03 EST news273429766 Dissecting the mechanisms implicated in cell architecture should provide new insights for understanding development and tissue morphogenesis in general. An European study focused on the role of the Notch signalling pathway in regulating cell architecture. http://medicalxpress.com/news/2012-10-notch-cell-architecture-potential-implications.html Cancer Fri, 05 Oct 2012 08:25:25 EST news268644288 As outlined in a study published in Developmental Cell, researchers have discovered a novel function for p27 in the control of interneuron migration in the developing cerebral cortex. http://medicalxpress.com/news/2012-10-cortex-protein.html Medical research Tue, 02 Oct 2012 08:39:45 EST news268385955 New research indicates marijuana-like compounds called endocannabinoids alter genes and biological signals critical to the formation of a normal placenta during pregnancy and may contribute to pregnancy complications like preeclampsia. http://medicalxpress.com/news/2012-09-implicates-marijuana-pregnancy-problems.html Medical research Wed, 12 Sep 2012 10:04:48 EST news266663078 (Medical Xpress)—In a study to decipher clues about how prostate cancer cells grow and become more aggressive, Johns Hopkins urologists have found that reduction of a specific protein is correlated with the aggressiveness of prostate cancer, acting as a red flag to indicate an increased risk of cancer recurrence. Their findings are reported online in the Proceedings of the National Academy of Sciences on Aug. 27, 2012. http://medicalxpress.com/news/2012-08-team-biological-indicator-aggressive-recurrent.html Cancer Mon, 27 Aug 2012 18:14:37 EST news265310066 By identifying a key protein that tells certain breast cancer cells when and how to move, researchers at Michigan State University hope to better understand the process by which breast cancer spreads, or metastasizes. http://medicalxpress.com/news/2012-08-potential-cancer-roadblock.html Cancer Wed, 01 Aug 2012 14:20:01 EST news263048767 European scientists joined forces to unravel how a physiological process such as inflammation can turn pathological. Project findings have the potential to provide answers to many inflammatory disorders. http://medicalxpress.com/news/2012-07-mechanisms-chronic-inflammation.html Inflammatory disorders Fri, 27 Jul 2012 09:20:18 EST news262599613 It is not unusual for babies to be born with congenital heart defects. This is because the development of the heart in the embryo is a process which is not only extremely complex, but also error-prone. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim have now identified a key molecule that plays a central role in regulating the function of stem cells in the heart. As a result, not only could congenital heart defects be avoided in future, but new ways of stimulating the regeneration of damaged hearts in adults may be opened up. http://medicalxpress.com/news/2012-07-finished-heart-stem-cells.html Medical research Thu, 12 Jul 2012 12:26:29 EST news261314746 (Medical Xpress) -- Discoveries by a Yale-led team of scientists could lead the way for development of new therapies for treating fibrosis and tumor metastasis. The researchers have both uncovered a signaling pathway that promotes cell migration in certain forms of pulmonary fibrosis, a deadly lung disease, and developed a drug treatment that may block the cancer cell migration. The study appears in the Advance Online Publication of Nature Cell Biology. http://medicalxpress.com/news/2012-05-cell-migration-block-fibrosis-cancer.html Medical research Mon, 21 May 2012 09:14:01 EST news256810421 A new class of agents known as c-Src inhibitors is being tested in a number of different ways to treat breast cancer, but researchers at Georgetown Lombardi Comprehensive Cancer Center caution that they should not be used in combination with estrogen to treat endocrine resistant breast cancer. http://medicalxpress.com/news/2012-04-specific-agents-worse-endocrine-resistant.html Cancer Mon, 02 Apr 2012 15:50:01 EST news252586174 A new study by University of Kentucky researchers provides insight into developing new treatment strategies for basal-like breast cancer, commonly known as triple-negative breast cancer. This cancer is associated with early metastasis and resistance to chemotherapy and occurs at women at a younger age. http://medicalxpress.com/news/2012-03-treatments-breast-cancer.html Cancer Wed, 14 Mar 2012 11:23:53 EST news250943025 The diagnosis of localized bladder cancer carries an 80 percent five-year survival rate, but once the cancer spreads, the survival rate at even three years is only 20 percent. A major study published today in the Journal of Clinical Investigation not only shows how bladder cancer metastasizes to the lungs but pinpoints a method for stopping this spread. http://medicalxpress.com/news/2012-03-major-bladder-cancer-metastasizing-lungs.html Cancer Mon, 12 Mar 2012 12:21:03 EST news250773655 Researchers have combined bioactive peptides to successfully stimulate wound healing. The in vitro and in vivo study, published today in PLoS ONE, demonstrates that the combination of two peptides stimulates the growth of blood vessels and promotes re-growth of tissue. Further development of these peptides could lead to a new treatment for chronic and acute wounds. http://medicalxpress.com/news/2012-02-bioactive-peptides-wound-vivo.html Medical research Fri, 24 Feb 2012 09:55:53 EST news249299746 Inflammatory breast cancer (IBC) is the most lethal form of breast cancer . It spreads easily through the lymphatic and blood vessels, forming metastasis which can lead to multi-organ failure. New research published in BioMed Central's open access journal Cell Communication and Signaling demonstrates how IBC cells use IL-8, secreted as part of the anti-inflammatory response by a specific set of white blood cells (monocytes), to increase fibronectin expression. http://medicalxpress.com/news/2012-02-metastatic-breast-cancer-hitches-free.html Immunology Fri, 10 Feb 2012 05:30:01 EST news248073643 Interferon-stimulated gene 15 (ISG15), a ubiquitin like protein, is highly elevated in a variety of cancers including breast cancer. How the elevated ISG15 pathway contributes to tumorigenic phenotypes remains unclear and is the subject of a study published in the January 2012 issue of Experimental Biology and Medicine. http://medicalxpress.com/news/2012-01-isg15-therapeutic-breast-cancer-cell.html Cancer Wed, 11 Jan 2012 16:26:47 EST news245521503 Research led by Dr. Suresh Alahari, the Fred Brazda Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans and its Stanley S. Scott Cancer Center, has found that a protein discovered by his laboratory can inhibit the growth of breast cancer cells. The research will be published September 14, 2011 online in the Journal of the National Cancer Institute. http://medicalxpress.com/news/2011-09-protein-suppress-breast-cancer-growth.html Cancer Wed, 14 Sep 2011 16:30:53 EST news235236613 Researchers at the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, identified for the first time the key role specific microRNAs (miRNAs) play in melanoma metastasis to simultaneously cause cancer cells to invade and immunosuppress the human body's ability to fight abnormal cells. The new study is published in the July 11, 2011 issue of the journal Cancer Cell. http://medicalxpress.com/news/2011-07-key-role-micrornas-melanoma-metastasis.html Cancer Mon, 11 Jul 2011 17:36:16 EST news229624314 (Medical Xpress) -- Scientists at Karolinska Institutet have discovered that a gene linked to dyslexia has a surprising biological function: it controls cilia, the antenna-like projections that cells use to communicate. http://medicalxpress.com/news/2011-06-unexpected-function-dyslexia-gene.html Genetics Mon, 20 Jun 2011 05:09:41 EST news227765318 Neuroepithelial stem cells, the early progenitors for much of the nervous system, need to maintain a keen sense of direction in order to properly manage replication, migration and maturation. These cells are highly polarized, and exclusively initiate cell division at their apical (top) end rather than at their basal (bottom) end, although it has remained a mystery how they determine which way is up. http://medicalxpress.com/news/2011-04-key-nervous-blocking-protein-stem.html Neuroscience Fri, 29 Apr 2011 11:30:02 EST news223294822