http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Declining levels of the protein BubR1 occur when both people and animals age, and contribute to cell senescence or deterioration, weight loss, muscle wasting and cataracts. Mayo Clinic researchers have shown that adult progenitor or stem cells—important for repair and regeneration of skeletal muscle and maintenance of healthy fat tissue—are subject to cellular senescence, and that clearance of these cells limits age-related deterioration of these tissues. The findings appear today online in the journal Cell Reports. http://medicalxpress.com/news/2013-04-stem-cell-senescence-aging.html Medical research Thu, 18 Apr 2013 12:42:21 EST news285507734 Researchers from the University of South Florida and colleagues at the James A. Haley Veterans' Hospital studying the long-term consequences of traumatic brain injury (TBI) using rat models, have found that, overtime, TBI results in progressive brain deterioration characterized by elevated inflammation and suppressed cell regeneration. However, therapeutic intervention, even in the chronic stage of TBI, may still help prevent cell death. http://medicalxpress.com/news/2013-01-long-term-consequences-traumatic-brain-injury.html Neuroscience Fri, 04 Jan 2013 16:51:40 EST news276540691 Resuscitation, cell regeneration, a new high blood pressure treatment and developments in devices for treating stroke are among the key scientific findings that make up this year's top cardiovascular and stroke research identified by the American Heart Association and American Stroke Association. http://medicalxpress.com/news/2012-12-advances-heart-disease.html Cardiology Tue, 18 Dec 2012 07:01:55 EST news275036426 The World Health Organization (WHO) has declared type 2 diabetes as the epidemic of the 21st century. A study is focusing on understanding the mechanisms underlying insulin resistance and the role of beta-cell regeneration. http://medicalxpress.com/news/2012-10-role-beta-cell-regeneration-diabetes.html Diabetes Wed, 10 Oct 2012 08:16:30 EST news269075783 A team headed by Eduardo Soriano at the Institute for Research in Biomedicine (IRB Barcelona) has published a study in Nature Communications describing a new family of six genes whose function regulates the movement and position of mitochondria in neurons. Many neurological conditions, including Parkinson's and various types of Charcot-Marie-Tooth disease, are caused by alterations of genes that control mitochondrial transport, a process that provides the energy required for cell function. http://medicalxpress.com/news/2012-05-discovery-family-key-mitochondrial-proteins.html Medical research Wed, 09 May 2012 11:21:08 EST news255781179 A new study in Nature Medicine describes how different types of immune system T-cells alternately discourage and encourage stem cells to regrow bone and tissue, bringing into sharp focus the importance of the transplant recipient's immune system in stem cell regeneration. http://medicalxpress.com/news/2011-11-recipient-immune-stem-cell-regeneration.html Medical research Sun, 20 Nov 2011 13:00:22 EST news241013089 One of the holy grails in diabetes research is to discover molecules that stimulate beta cell growth and to find drugs that target these molecules. Now, JDRF-funded researchers in collaboration with the pharmaceutical company Hoffmann-La Roche, have done both, discovering not only a protein that regulates beta cell growth, but also a chemical compound that stimulates it. The work appears in the September 7 issue of Cell Metabolism. http://medicalxpress.com/news/2011-09-scientists-uncover-ways-pancreatic-beta.html Medical research Tue, 06 Sep 2011 14:48:20 EST news234539287