http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. To get a clear picture of how humans and other mammals form memories and find their way through their surroundings, neuroscientists must pay more attention to a broad range of animals rather than focus on a single model species, say two University of Maryland (UMD) researchers, Katrina MacLeod and Cynthia Moss. Their new comparative study of bats and rats reports differences between the species that suggest the need to revise models of spatial navigation. http://medicalxpress.com/news/2013-04-analysis-species-required-brain.html Neuroscience Mon, 29 Apr 2013 09:24:36 EST news286446269 Today, the International and American Associations for Dental Research (IADR/AADR) published a paper titled "ß-catenin is Required in Odontoblasts for Tooth Root Formation." The paper, written by lead authors Tak-Heun Kim and Cheol-Hyeon Bae, Chonbuk National University Korea School of Dentistry, Laboratory for Craniofacial Biology, is published in the IADR/AADR Journal of Dental Research. http://medicalxpress.com/news/2013-01-beta-catenin-molecule-required-tooth-root.html Dentistry Wed, 23 Jan 2013 14:57:35 EST news278175439 Research at the University of Edinburgh tracked electrical signals in the part of the brain linked to spatial awareness. http://medicalxpress.com/news/2013-01-rhythms-brain.html Neuroscience Thu, 10 Jan 2013 11:01:00 EST news277038053 (Medical Xpress)—The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death. New work on Akt's role in cancer stem cell biology from the lab of senior author Honglin Zhou, MD, PhD and Weihua Li, co-first author, both from the Center for Resuscitation Sciences, Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, and Xiaowei Xu, Department of Pathology and Laboratory Medicine, appears in Molecular Cell. The findings were also highlighted in Nature and Science reviews. http://medicalxpress.com/news/2012-12-protein-kinase-akt-arbiter-cancer.html Cancer Thu, 20 Dec 2012 07:15:51 EST news275210140 (Medical Xpress)—A University of Cincinnati (UC) cancer biology team reports breakthrough findings about specific cellular mechanisms that may help overcome endocrine (hormone) therapy-resistance in patients with estrogen-positive breast cancers, combating a widespread problem in effective medical management of the disease. http://medicalxpress.com/news/2012-11-clues-tamoxifen-resistant-breast-cancer.html Cancer Fri, 02 Nov 2012 10:44:17 EST news271071834 New study from the University of Haifa discovers: Link found between Alzheimer's disease and protein regulation in the brain brings hope for new treatments http://medicalxpress.com/news/2012-10-link-alzheimer-disease-protein-brainhope.html Alzheimer's disease & dementia Mon, 22 Oct 2012 09:55:12 EST news270118503 Turning the volume up too high on your headphones can damage the coating of nerve cells, leading to temporary deafness; scientists from the University of Leicester have shown for the first time. http://medicalxpress.com/news/2012-08-earphones-potentially-dangerous-noise-jet.html Medical research Wed, 29 Aug 2012 11:06:40 EST news265457188 Buttery shrimp. Fried eggs. Burgers and fries. New research suggests there may be a biological reason why fatty and cholesterol-rich foods are so appealing together. http://medicalxpress.com/news/2012-06-zebrafish-dietary-fat-cholesterol-absorption.html Medical research Fri, 22 Jun 2012 17:06:34 EST news259603586 Cellular mechanisms that enable healthy growth can spiral out of control and give rise to cancer. For this reason, signal transduction pathways that underlie cell growth are tightly regulated, with multiple checkpoints and extensive cross-talk in between signal cascades that drive cell division and differentiation. Stephen Cohen and co-workers at the A*STAR Institute of Molecular and Cell Biology have identified a new link between growth controlling microRNAs and this cellular circuitry. http://medicalxpress.com/news/2012-06-micrornas-link-pathways-growth-animal.html Medical research Wed, 20 Jun 2012 09:40:08 EST news259402889 Fear conditioning using sound and taste aversion, as applied to mice, have revealed interesting information on the basis of memory allocation. http://medicalxpress.com/news/2012-06-neurological-basis-memory.html Neuroscience Mon, 18 Jun 2012 13:25:16 EST news259244323 (Medical Xpress) -- Johns Hopkins researchers say they have discovered one of the most important cellular mechanisms driving the growth and progression of meningioma, the most common form of brain and spinal cord tumor. A report on the discovery, published in the journal Molecular Cancer Research, could lead the way to the discovery of better drugs to attack these crippling tumors, the scientists say. http://medicalxpress.com/news/2012-06-pathway-common-brain-spinal-cord.html Cancer Wed, 13 Jun 2012 06:33:20 EST news258787990 Scientists from the University of Utah School of Medicine have discovered that a mouse protein called IFITM3 contributes to the body's defense against some types of viral infections by binding to an enzyme responsible for regulating the pH of a cell's waste disposal system. This finding, published in the March 30, 2012, issue of Innate Immunity, sheds light on the cellular mechanisms involved in flu resistance and opens up potential new avenues of research for anti-viral medications. http://medicalxpress.com/news/2012-04-reveals-insight-key-protein-viral.html Immunology Mon, 02 Apr 2012 09:16:56 EST news252576998 Researchers in Rhode Island Hospital's Cardiovascular Research Center have published two new studies focusing on the causes of arrhythmia and sudden cardiac death (SCD) when a genetic disorder is present. The studies use a first-ever genetic animal model the researchers developed in 2008 to further their understanding of a genetic disorder known as Long QT Syndrome (LQTS). The first study identified differential conditions and cellular mechanisms that can trigger SCD when LQTS is a factor, and the second study, for the first time, directly links sex hormones and the incidence of arrhythmia and SCD. Their findings are published in the Journal of Physiology and the HeartRhythm Journal. http://medicalxpress.com/news/2012-01-uncover-keys-sudden-cardiac-death.html Cardiology Tue, 17 Jan 2012 15:03:49 EST news246035019 New research reveals that insulin applied in therapeutic doses selectively stimulates the formation of new elastic fibers in cultures of human aortic smooth muscle cells. These results advance the understanding of the molecular and cellular mechanisms of diabetic vascular disease. The study is published in the February issue of the American Journal of Pathology. http://medicalxpress.com/news/2012-01-insulin-therapy-atherosclerotic-lesions-diabetic.html Diseases, Conditions, Syndromes Mon, 09 Jan 2012 13:01:04 EST news245336456 New research by scientists at the Scripps Research Institute has underlined the power of an endogenous anti-stress peptide in the brain to prevent and even reverse some of the cellular effects of acute alcohol and alcohol dependence in animal models. The work could lead to the development of novel drugs to treat alcoholism. http://medicalxpress.com/news/2011-12-underlines-potential-anti-stress-peptide-block.html Psychology & Psychiatry Fri, 09 Dec 2011 12:49:58 EST news242657347 A team led by scientists from Johns Hopkins and the National Institutes of Health has discovered a new genetic mutation for amyotrophic lateral sclerosis (ALS) and a related disease called frontotemporal dementia (FTD) that appears to account for more than a third of all inherited cases of these diseases. The researchers show in a new study published online on September 21 in Neuron that this mutation, found within a gene called C9ORF72, is about twice as common as all the other mutations discovered thus far for the disease combined. http://medicalxpress.com/news/2011-09-human-genetics-common-als-dementia.html Neuroscience Wed, 21 Sep 2011 12:54:33 EST news235828454 Though it generally is known that obesity dramatically increases the risk for type 2 diabetes, the biological mechanisms for that connection still are unclear. http://medicalxpress.com/news/2011-07-toxicity-fatty-acids-links-obesity.html Diseases, Conditions, Syndromes Wed, 20 Jul 2011 12:25:52 EST news230383542 (Medical Xpress) -- Tiny electrodes have been coated with a drug-loaded polymer in an attempt to design an implant capable of detecting a number of neurological symptoms, such as those associated with an epileptic seizure, and treating them simultaneously. http://medicalxpress.com/news/2011-06-technology-brain-implant-seizures.html Medical research Thu, 02 Jun 2011 05:21:33 EST news226210880