http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Data from a number of clinical trials presented today at the International Liver Congress 2013 shed new light on the use of TACE and SIRT in the treatment of hepatocellular carcinoma (HCC). http://medicalxpress.com/news/2013-04-tace-sirt-treatment-patients.html Cancer Fri, 26 Apr 2013 06:07:58 EST news286175256 Epithelial cells are homebodies – they like to attach to things and becoming detached initiates a form of cell suicide known as anoikis (literally "homeless" in Latin). But in order for cancer cells to metastasize they have to leave their homes and to survive while traveling they must resist anoikis – like a third-grader at sleep-away camp. Cancer cells do this by taking a page from the neuron playbook. Neurons are by nature unbound – they grow and link to each other and not to a substrate. Neurons have a protein called TrkB that allows them to survive anoikis; healthy epithelial cells don't have TrkB and so are susceptible to anoikis. http://medicalxpress.com/news/2012-11-microrna-triple-negative-breast-cancer-homesick.html Cancer Wed, 21 Nov 2012 16:59:43 EST news272739573 Researchers at Case Western Reserve University School of Medicine have discovered a mutant form of the gene, Chk1, that when expressed in cancer cells, permanently stopped their proliferation and caused cell death without the addition of any chemotherapeutic drugs. This study illustrates an unprecedented finding, that artificially activating Chk1 alone is sufficient to kill cancer cells. http://medicalxpress.com/news/2012-07-gene-permanently-cancer-cell-proliferation.html Cancer Wed, 01 Aug 2012 00:20:01 EST news262978935 Researchers have created the first mouse model demonstrating the role of a cancer promoting gene, Astrocyte elevated gene-1 (AEG-1), in hepatocellular carcinoma, or liver cancer. The mouse model represents a critical step in understanding the molecular mechanisms of liver cancer progression and could lead to novel therapies for the disease. http://medicalxpress.com/news/2012-07-scientists-mouse-therapies-liver-cancer.html Cancer Fri, 06 Jul 2012 18:46:54 EST news260819209 Severe pain is a major symptom of pancreatic cancer. The results of a new study show that four different factors involved in the growth and maintenance of nerves are elevated in a mouse model of pancreatic cancer. This is a step forward in understanding the relationship between the development of pain and the progression of pancreatic cancer. http://medicalxpress.com/news/2012-06-nerve-growth-factors-elevated-pancreatic.html Cancer Tue, 19 Jun 2012 11:06:03 EST news259322748 The largest study ever on the effect of genetic variability on the toxicity of chemotherapy in breast cancer shows that it is possible to predict which patients are most likely to suffer serious side effects, a researcher will tell the 8th European Breast Cancer Conference (EBCC-8) today (Friday). Dr. Christof Vulsteke, from the Catholic University of Leuven, Belgium, will explain how his team's research is an important step towards achieving a personalised chemotherapy regime for each patient. http://medicalxpress.com/news/2012-03-individual-genetic-variation-chemotherapy-side.html Cancer Fri, 23 Mar 2012 03:51:35 EST news251693480 Researchers have developed a new genetic screening tool that will aid in the investigation of possible treatments for patients with melanoma and the unique genetic mutations that may accompany the disease, according to data presented at the AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics, held Nov. 12-16, 2011. http://medicalxpress.com/news/2011-11-panel-melanoma-mutations-door-treatment.html Cancer Tue, 15 Nov 2011 16:04:03 EST news240595419 A protein activated by certain drugs already approved for treating Type II diabetes may slow or stop the spread of breast tumors. http://medicalxpress.com/news/2011-05-diabetic-drug-cancer.html Cancer Tue, 31 May 2011 16:20:00 EST news226077579