http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Breast cancer characterized as "triple negative" carries a poor prognosis, with limited treatment options. In some cases, chemotherapy doesn't kill the cancer cells the way it's supposed to. New research from Western University explains why some cancer cells don't respond to chemotherapy, and identifies a mechanism to rectify that. http://medicalxpress.com/news/2013-05-cancer-cells-responsive-chemotherapy.html Cancer Thu, 23 May 2013 17:23:58 EST news288548605 Mathematical prediction models are better than doctors at predicting the outcomes and responses of lung cancer patients to treatment, according to new research presented today (Saturday) at the 2nd Forum of the European Society for Radiotherapy and Oncology (ESTRO). http://medicalxpress.com/news/2013-04-mathematical-out-perform-doctors-cancer-patients.html Cancer Sat, 20 Apr 2013 06:54:06 EST news285659630 (Medical Xpress)—Researchers from the University of Alberta are abuzz after using fruit flies to find new ways of taking advantage of caffeine's lethal effects on cancer cells—results that could one day be used to advance cancer therapies for people. http://medicalxpress.com/news/2013-04-abuzz-caffeine-cancer-cell-killer.html Cancer Thu, 18 Apr 2013 06:49:44 EST news285486576 The fatigue experienced by patients undergoing cancer treatments has long been recognized by health care providers, although its causes and ways to manage it are still largely unknown. http://medicalxpress.com/news/2013-03-wayne-state-exhaustion-cancer-patients.html Cancer Fri, 08 Mar 2013 13:25:26 EST news281971470 (Medical Xpress)—Patients with advanced, recurrent, or persistent cervical cancer that was not curable with standard treatment who received the drug bevacizumab (Avastin) lived 3.7 months longer than patients who did not receive the drug, according to an interim analysis of a large, randomized clinical trial. http://medicalxpress.com/news/2013-02-bevacizumab-significantly-survival-patients-recurrent.html Cancer Fri, 08 Feb 2013 07:50:01 EST news279531567 Poorer lung cancer patients in the developed world are significantly less likely to receive treatment than richer patients, researchers from Newcastle University have found. This inequality in treatment may contribute to the higher death rates for lung cancer in poorer patients. http://medicalxpress.com/news/2013-02-poorer-patients-lung-cancer-treatment.html Cancer Fri, 08 Feb 2013 06:50:03 EST news279527851 Chemotherapy is one of the most common treatments for cancer patients. However, many patients suffer from serious side-effects and a large proportion does not respond to the treatment. Researchers from the Biotech Research and Innovation Centre (BRIC) and Center for Healthy Aging, University of Copenhagen, now show that the gene FBH1 helps turn up the effect of chemotherapy. http://medicalxpress.com/news/2013-01-gene-effect-chemotherapy.html Cancer Tue, 29 Jan 2013 12:05:49 EST news278683542 (Medical Xpress)—The assumption that childhood cancer in developing countries is prohibitively expensive to treat is challenged by new research contributed to by the University of Sydney. http://medicalxpress.com/news/2012-12-childhood-cancer-countries-expensive-believed.html Cancer Mon, 03 Dec 2012 07:08:20 EST news273740887 Researchers from Inserm and CNRS from the Institute for genetics and molecular and cellular biology (IGBMC) and from the Research Institute at the Strasbourg school of biotechnology (Irebs) have focussed their efforts on PARG, currently thought to be a promising new therapeutic target in the treatment of cancer. Their work has revealed the role of this molecule in regulating gene expression. The results were published on 25 October 2012 in the on-line Molecular Cell review. http://medicalxpress.com/news/2012-10-reveal-molecule-function-terms-cancer.html Cancer Tue, 30 Oct 2012 12:10:02 EST news270815672 Crizotinib is effective in shrinking tumors in patients with anaplastic lymphoma receptor tyrosine kinase (ALK) positive non-small cell lung cancer, a cancer commonly found in people who never smoked, and should be the standard of care for advanced stages of this disease, according to research presented at the 2012 Chicago Multidisciplinary Symposium in Thoracic Oncology. This symposium is sponsored by the American Society of Clinical Oncology (ASCO), the American Society for Radiation Oncology (ASTRO), the International Association for the Study of Lung Cancer (IASLC) and The University of Chicago. http://medicalxpress.com/news/2012-09-crizotinib-tumor-size-patients-alk.html Cancer Thu, 06 Sep 2012 15:07:50 EST news266162854 Research suggests that patients with leukemia sometimes relapse because standard chemotherapy fails to kill the self-renewing leukemia initiating cells, often referred to as cancer stem cells. In such cancers, the cells lie dormant for a time, only to later begin cloning, resulting in a return and metastasis of the disease. http://medicalxpress.com/news/2012-07-block-pathway-cancer-cell-replication.html Cancer Mon, 02 Jul 2012 12:06:26 EST news260449564 Results of some preclinical trials have shown that low doses of the antidiabetic drug metformin may effectively destroy cancer stem cells, a group of cells that are considered to be responsible for tumor initiation and, because they are resistant to standard chemotherapies, tumor relapse. http://medicalxpress.com/news/2012-06-metformin-treatment-cancer-stem-cell.html Cancer Tue, 19 Jun 2012 15:30:18 EST news259332583 Blocking a protein in the heart that is produced under stressful conditions could be a strategy to prevent cardiac damage that results from chemotherapy, a new study suggests. http://medicalxpress.com/news/2012-05-heart-chemo-linked-stress-cardiac.html Cardiology Mon, 21 May 2012 15:00:42 EST news256820399 For patients with metastatic soft-tissue sarcoma whose disease has progressed following standard chemotherapy, treatment with pazopanib (a drug that targets the growth of new cancer-related blood vessels) nearly tripled progression-free survival (PFS) compared with placebo, according to results of the PALETTE trial, published Online First in The Lancet. This is the first time a randomised phase 3 trial in metastatic soft-tissue sarcoma has shown improvement in PFS. http://medicalxpress.com/news/2012-05-therapy-pazopanib-prolongs-progression-free-survival.html Cancer Tue, 15 May 2012 18:30:03 EST news256311817 Engineers and scientists at the University of Glasgow are developing a new method of treating head and neck cancers they believe will make therapy more targeted and effective. http://medicalxpress.com/news/2012-05-treatment-neck-cancers-uk.html Cancer Mon, 07 May 2012 08:37:22 EST news255598619 Oregano, the common pizza and pasta seasoning herb, has long been known to possess a variety of beneficial health effects, but a new study by researchers at Long Island University (LIU) indicates that an ingredient of this spice could potentially be used to treat prostate cancer, the second leading cause of cancer death in American men. http://medicalxpress.com/news/2012-04-component-pizza-seasoning-herb-oregano.html Cancer Tue, 24 Apr 2012 15:30:01 EST news254492818 Some breast cancer tumours may be resistant to a common chemotherapy treatment, suggests recent medical research at the University of Alberta. http://medicalxpress.com/news/2012-03-breast-cancer-tumors-resistant-common.html Cancer Tue, 27 Mar 2012 15:00:01 EST news252078641 Researchers at Wake Forest Baptist Medical Center have demonstrated that cancer of the appendix is different than colon cancer, a distinction that could lead to more effective treatments for both diseases. http://medicalxpress.com/news/2012-03-cancer-appendix.html Cancer Wed, 07 Mar 2012 15:37:23 EST news250357037 The first therapeutic cancer vaccine has now been approved by the FDA, and a diverse range of therapeutic cancer vaccines directed against a spectrum of tumor-associated antigens are currently being evaluated in clinical trials, according to a review published March 6 in the Journal of the National Cancer Institute. http://medicalxpress.com/news/2012-03-cancer-vaccines.html Cancer Tue, 06 Mar 2012 16:00:04 EST news250263787 When a 41-year-old woman was diagnosed with chronic-phase chronic myeloid leukemia, she received a bone marrow transplant and subsequent leukocyte infusion from her sister. These treatments controlled her leukemia, but seven years later, both sisters developed follicular lymphoma. http://medicalxpress.com/news/2011-12-sisters-lymphoma-evolution.html Cancer Mon, 12 Dec 2011 16:25:36 EST news242929530 Younger patients with diffuse large B-cell lymphoma given a more intensive regimen of chemotherapy combined with rituximab survive significantly longer, and are approximately twice as likely to remain in remission 3 years later, compared with patients given standard chemotherapy treatment plus rituximab, according to an article published Online First in the Lancet. http://medicalxpress.com/news/2011-11-intensive-chemotherapy-recurrence-survival-younger.html Cancer Thu, 24 Nov 2011 18:30:03 EST news241362774 A Kansas State University professor is trying to create a patient-friendly treatment to help the more than 220,000 people who are diagnosed with lung cancer each year. http://medicalxpress.com/news/2011-08-bull-eye-therapy-combat-lung-cancer.html Cancer Mon, 22 Aug 2011 11:18:46 EST news233230706 Although chemotherapy is used to kill cancer cells, it can also have a strong toxic effect on normal cells such as bone marrow and blood cells, often limiting the ability to use and manage the chemotherapy treatment. Researchers at Fred Hutchinson Cancer Research Center reported at today's annual meeting of the American Society of Gene and Cell Therapy in Seattle that one possible approach to reduce this toxic effect on bone marrow cells is to modify the cells with a gene that makes them resistant to chemotherapy. http://medicalxpress.com/news/2011-05-gene-modified-stem-cells-bone-marrow.html Cancer Sat, 21 May 2011 05:36:52 EST news225174980