http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. (Medical Xpress)—Queen's University researchers have discovered how a key artery in a newborn baby's heart constricts and eventually closes when the baby takes its first breath and adjusts to the shock of being born. The discovery will give doctors new treatment options for problems such as blue babies. http://medicalxpress.com/news/2013-03-mystery-baby.html Medical research Tue, 05 Mar 2013 06:37:55 EST news281687867 (HealthDay)—Delivery of an SDF-1 encoding plasmid (JVS-100) acts a homing signal for stem cells and improves clinical status in patients with symptomatic heart failure due to ischemic cardiomyopathy (IsCM), according to a study published online Feb. 21 in Circulation Research. http://medicalxpress.com/news/2013-02-gene-therapy-stem-cells-heart.html Cardiology Fri, 22 Feb 2013 15:10:03 EST news280765743 In the first human study of its kind, researchers activated heart failure patients' stem cells with gene therapy to improve their symptoms, heart function and quality of life, according to a study in the American Heart Association journal Circulation Research. Researchers delivered a gene that encodes a factor called SDF-1 to activate stem cells like a "homing" signal. http://medicalxpress.com/news/2013-02-stem-cell-homing-heart-failure.html Cardiology Thu, 21 Feb 2013 16:01:52 EST news280684895 New research has shown the presence of a disease affecting small blood vessels, known as microangiopathy, in the bone marrow of diabetic patients. While it is well known that microangiopathy is the cause of renal damage, blindness and heart attacks in patients with diabetes, this is the first time that a reduction of the smallest blood vessels has been shown in bone marrow, the tissue contained inside the bones and the main source of stem cells. http://medicalxpress.com/news/2013-01-diabetes-distresses-bone-marrow-stem.html Diabetes Thu, 31 Jan 2013 16:00:01 EST news278869521 A certain enzyme, the CaM kinase II, keeps the cardiac muscle flexible. By transferring phosphate groups to the giant protein titin, it relaxes the muscle cells. This is reported by researchers led by Prof. Dr. Wolfgang Linke of the Institute of Physiology at the Ruhr Universität in the journal Circulation Research. http://medicalxpress.com/news/2013-01-enzyme-cam-kinase-ii-muscle.html Cardiology Thu, 17 Jan 2013 10:31:39 EST news277640781 Restoring diminished levels of a protein shown to prevent and reverse heart failure damage could also have therapeutic applications for patients with critical limb ischemia (CLI), suggests a new preclinical study published online October 9 in Circulation Research from researchers at the Center for Translational Medicine at Thomas Jefferson University . http://medicalxpress.com/news/2012-10-loss-heart-failure-protein-linked.html Medical research Wed, 10 Oct 2012 13:10:51 EST news269093441 Men with high risk for heart disease had lower blood pressure after drinking non-alcoholic red wine every day for four weeks, according to a new study in the American Heart Association journal Circulation Research. http://medicalxpress.com/news/2012-09-non-alcoholic-red-wine-high-blood.html Cardiology Thu, 06 Sep 2012 16:00:01 EST news266149119 It is a cellular component so scarce, some scientists even doubted its existence, and many others gave up searching for its molecular structure. Now a team led by researchers at Johns Hopkins has defined the protein structural composition of mitoKATP, a potassium channel in the mitochondria of the heart and other organs that is known to protect against tissue damage due to a heart attack or stroke. Importantly, the newly found channel strongly improves heart cell survival, demonstrating an essential life-saving role. http://medicalxpress.com/news/2012-07-year-quest-scientists-pin-elusive.html Cardiology Tue, 17 Jul 2012 16:00:03 EST news261750478 A cutting-edge method developed at the University of Michigan Center for Arrhythmia Research successfully uses stem cells to create heart cells capable of mimicking the heart's crucial squeezing action. http://medicalxpress.com/news/2012-06-method-cardiac-muscle-patches-stem.html Cardiology Tue, 19 Jun 2012 09:40:10 EST news259317555 Scientists at Duke University Medical Center have shown the ability to turn scar tissue that forms after a heart attack into heart muscle cells using a new process that eliminates the need for stem cell transplant. http://medicalxpress.com/news/2012-04-scar-tissue-heart-muscle-stem.html Cardiology Thu, 26 Apr 2012 16:00:02 EST news254665952 LMU researchers developed a new strategy for the treatment of stroke, which could help to improve blood flow to ischemic brain. Strokes are due to a localized reduction in the blood supply to the brain, mainly due to the blockage of a vessel by a blood clot. This can lead to the death and irreversible loss of nerve cells. In about 90% of cases, no dedicated treatment is available that can effectively prevent serious damage following an acute stroke. http://medicalxpress.com/news/2012-03-approach-therapy.html Cardiology Mon, 05 Mar 2012 11:53:09 EST news250170773 Severe heart damage in people who are obese and diabetic is linked with a pancreatic hormone called amylin, UC Davis researchers have found. http://medicalxpress.com/news/2012-02-pancreatic-hormone-linked-severe-heart.html Cardiology Thu, 16 Feb 2012 17:10:04 EST news248634591 The size of a heart attack and subsequent left-ventricular function are significantly different based on the time of day onset of ischemia, according to a first of its kind study in humans, published online Nov. 17 in Circulation Research. The greatest amount of injury to the heart occurs when individuals have a heart attack between 1:00am and 5:00am. http://medicalxpress.com/news/2011-11-severity-heart-day.html Cardiology Mon, 21 Nov 2011 10:19:50 EST news241093141 Researchers from Mount Sinai School of Medicine have discovered the therapeutic benefit of fetal stem cells in helping the maternal heart recover after heart attack or other injury. The research, which marks a significant advancement in cardiac regenerative medicine, was presented today at the American Heart Association's (AHA) Scientific Sessions 2011 in Orlando, Florida, and is also published in the current issue of Circulation Research, a journal of the AHA. http://medicalxpress.com/news/2011-11-fetal-stem-cells-placenta-maternal.html Cardiology Mon, 14 Nov 2011 17:14:45 EST news240513126 Stem cell therapies promise to regenerate the infarcted heart through the replacement of dead cardiac cells and stimulation of the growth of new vessels. New research has found the transplantation of stem cells that reside in human veins can help in the recovery of a heart attack. The findings could lead, in the next few years, to the first human clinical trial. http://medicalxpress.com/news/2011-08-mural-cells-saphenous-vein-long-term.html Cardiology Thu, 25 Aug 2011 17:05:20 EST news233510709 The internally-driven daily cycle of blood pressure changes doesn't appear to be linked to the known increase in morning heart attacks, according to a study in Circulation Research: Journal of the American Heart Association. http://medicalxpress.com/news/2011-04-blood-pressure-internally-driven-daily.html Cardiology Thu, 07 Apr 2011 16:17:04 EST news221411815