http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Two genome-wide association studies and a subsequent meta-analysis have found that certain genetic variations are associated with susceptibility to Helicobacter pylori, a bacteria that is a major cause of gastritis and stomach ulcers and is linked to stomach cancer, findings that may help explain some of the observed variation in individual risk for H pylori infection, according to a study in the May 8 issue of JAMA. http://medicalxpress.com/news/2013-05-genetic-variations-susceptibility-bacteria-linked.html Diseases, Conditions, Syndromes Tue, 07 May 2013 16:00:01 EST news287141875 Researchers at Mayo Clinic Cancer Center have identified a novel gene that can contribute to a woman's susceptibility for developing ovarian cancer. Researchers identified the gene, called HNF1B, through large-scale analysis of more than 16,000 women with ovarian cancer and more than 26,000 healthy women. Results of the study are published in the current issue of the journal Nature Communications. http://medicalxpress.com/news/2013-03-gene-ovarian-cancer.html Cancer Wed, 27 Mar 2013 12:11:50 EST news283605093 Dalhousie researchers link binge eating among university-aged women with strained mother-daughter relationships in a recent study published in the journal Eating Behaviors. http://medicalxpress.com/news/2013-03-links-binge-strained-mother-daughter-relationships.html Health Wed, 06 Mar 2013 08:41:22 EST news281781394 (Medical Xpress)—Researchers have identified a critical protein role in the metastasis of melanoma, the most serious form of skin cancer. Inhibition of the protein known as adenosine diphosphate ribosylation factor 6 (ARF6) reduces the spread of melanoma to the lungs in mice, according to a study published in the March 5 issue of Science Signaling online, suggesting that targeting ARF6 may be an effective approach to preventing melanoma metastasis. http://medicalxpress.com/news/2013-03-melanoma-inhibiting-key-protein-metastasis.html Cancer Tue, 05 Mar 2013 07:50:02 EST news281690616 Reducing fear and stress following a traumatic event could be as simple as providing a protein synthesis blocker to the brain, report a team of researchers from McLean Hospital, Harvard Medical School, McGill University, and Massachusetts General Hospital in a paper published in the March 4 issue of Proceedings of the National Academy of Sciences. http://medicalxpress.com/news/2013-03-protein-synthesis-blocker-key-effects.html Neuroscience Mon, 04 Mar 2013 16:07:18 EST news281635629 (HealthDay)—Compared with control patients without cancer, survivors of some cancers receive different quality of care on certain chronic and acute indicators, according to research published online Feb. 11 in the Journal of Clinical Oncology. http://medicalxpress.com/news/2013-02-cancer-affects-quality-survivors.html Cancer Thu, 14 Feb 2013 15:10:01 EST news280073343 A new study from Karolinska Institutet shows that patients with multiple sclerosis (MS) run a high risk of heart attack, stroke and heart failure, regardless of migration background. According to principal investigator Tahereh Moradi, the study is the first in the world to examine the risk of cardiovascular diseases in male and female MS patients with both non-immigrant and immigrant backgrounds. http://medicalxpress.com/news/2013-02-high-cardiovascular-diseases-swedish-born-immigrant.html Neuroscience Mon, 04 Feb 2013 08:48:35 EST news279190107 A new study, to be published in the Feb. 7, 2013 issue of the American Journal of Human Genetics, expands and deepens the biological and genetic links between cardiovascular disease and schizophrenia. Cardiovascular disease (CVD) is the leading cause of premature death among schizophrenia patients, who die from heart and blood vessel disorders at a rate double that of persons without the mental disorder. http://medicalxpress.com/news/2013-01-links-schizophrenia-cardiovascular-disease.html Genetics Thu, 31 Jan 2013 12:00:09 EST news278854042 Scientists at the Forsyth have gained new insight on how Tuberculosis (TB) remains a global epidemic. Although drugs have been available to fight TB for 50 years, the disease still infects nearly 2.2 billion people worldwide and causes 1.7 million annual deaths. This is largely attributed to the bacteria's ability to stay dormant in the human body and later resurface as active disease. The Forsyth team, and its collaborators from Stanford University, has recently discovered that Mycobacterium tuberculosis, the bacteria that causes TB, can lay dormant and thrive within bone marrow stem cells. http://medicalxpress.com/news/2013-01-scientists-gain-latent-tuberculosis.html Diseases, Conditions, Syndromes Wed, 30 Jan 2013 14:00:01 EST news278766332 One in every 10 Americans has diabetes, and a third or more of those with the condition will develop kidney disease. It may be possible to live a long and healthy life with diabetes, but once kidney disease develops, the risk of dying prematurely increases significantly, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The findings have significant clinical implications for the prevention and treatment of kidney disease in people with diabetes. http://medicalxpress.com/news/2013-01-kidney-disease-accounts-dying-early.html Diseases, Conditions, Syndromes Thu, 24 Jan 2013 17:00:07 EST news278265346 (HealthDay)—Serum metal levels of cobalt and chromium are elevated at all postoperative time points up to 36 months following metal-on-metal lumbar disc replacement, according to research published in the November issue of the European Spine Journal. http://medicalxpress.com/news/2012-12-serum-metal-lumbar-disc.html Other Sat, 22 Dec 2012 17:00:01 EST news275416429 People with asthma have an increased risk of pulmonary embolism, according to new research. http://medicalxpress.com/news/2012-12-asthmatics-pulmonary-embolism.html Inflammatory disorders Wed, 19 Dec 2012 19:00:01 EST news275158441 A new study by Douglas Mental Health University Institute researchers shows altered body rhythms of the hormone melatonin in Premenstrual dysphoric disorder (PMDD) women with insomnia. This finding may help explain some of the sleep disruptions experienced by women with PMDD, also known as premenstrual syndrome. PMDD is a mood disorder which appears in the week preceding menses, and affects about 3-8% of women. PMDD sufferers can experience depression, tension, and irritability of sufficient intensity to interfere with daily activities and relationships. Disturbed sleep is also a common symptom of the disorder, with up to 70% of patients frequently reporting either poor sleep quality with increased awakenings or excessive sleepiness during the symptomatic phase. http://medicalxpress.com/news/2012-12-impaired-melatonin-secretion-role-premenstrual.html Medical research Wed, 19 Dec 2012 17:00:07 EST news275157631 One major cause of illness from food-borne diseases is the parasite Toxoplasma gondii (T. gondii). New insights into how the immune system combats T. gondii are provided in a study published by Cell Press December 13th in the journal Immunity. The findings could lead to the development of long-sought vaccines to protect against T. gondii and related parasites. http://medicalxpress.com/news/2012-12-long-sought-vaccines-deadly-parasite-closer.html Immunology Thu, 13 Dec 2012 12:00:11 EST news274620287 (HealthDay)—Men who have erectile dysfunction and low testosterone may get no extra benefit from adding the hormone to their Viagra prescription, a new study suggests. http://medicalxpress.com/news/2012-11-testosterone-gel-boost-viagra-effects.html Medical research Mon, 19 Nov 2012 17:13:06 EST news272567550 (Medical Xpress)—Researchers from the Department of Biomedical Engineering at Stony Brook University have developed a high-resolution, 3D optical Doppler imaging tomography technique that captures the effects of cocaine restricting the blood supply in vessels – including small capillaries – of the brain. The study, reported in Molecular Psychiatry, and with images on the journal's October 2012 cover, illustrates the first use of the novel neuroimaging technique and provides evidence of cocaine-induced cerebral microischemia, which can cause stroke. http://medicalxpress.com/news/2012-10-neuroimaging-technique-capturing-cocaine-devastating.html Psychology & Psychiatry Wed, 10 Oct 2012 17:51:28 EST news269110278 (HealthDay)—Compared with other anti-psoriatic therapies, systemic anti-inflammatory treatment of patients with severe psoriasis with biologic agents or methotrexate is associated with a lower combined risk of death, myocardial infarction, and stroke, according to research published online Sept. 11 in the Journal of Internal Medicine. http://medicalxpress.com/news/2012-09-choice-psoriasis-treatment-affects-cvd.html Immunology Thu, 27 Sep 2012 18:20:01 EST news267987071 Researchers at NYU School of Medicine have made a novel discovery that could have widespread clinical implications, potentially affecting everything from nutrient metabolism to obesity in children. http://medicalxpress.com/news/2012-08-early-exposure-antibiotics-impact-obesity.html Medications Wed, 22 Aug 2012 13:22:39 EST news264860550 (HealthDay) -- Researchers have uncovered more evidence that certain types of delays in brain development seem to be related to a heightened risk for attention-deficit hyperactivity disorder (ADHD). http://medicalxpress.com/news/2012-08-brain-growth-adhd.html Psychology & Psychiatry Wed, 15 Aug 2012 15:20:04 EST news264260102 A new study shows that the lack of a certain gene occurs in almost 28 percent of human breast cancers, playing a role in some 60,000 breast cancer cases in the United States and 383,000 worldwide this year. http://medicalxpress.com/news/2012-08-gene-deletion-quarter-breast-cancers.html Genetics Wed, 15 Aug 2012 04:17:35 EST news264223029 A compound that mops up debris of damaged cells from the bloodstream may be the first in a new class of drugs designed to address one of medicine's most difficult challenges -- stopping the formation of blood clots without triggering equally threatening bleeding. http://medicalxpress.com/news/2012-07-bloodstream-scavenger-inhibits-clotting.html Medical research Mon, 23 Jul 2012 16:17:53 EST news262279038 The study, published online this month in the journal Suicide and Life-Threatening Behavior, found that approximately one-third of adults who were physically abused in childhood had seriously considered taking their own life. These rates were five times higher than adults who were not physically abused in childhood. The findings suggest that children exposed to physical abuse may be at greater risk for suicidal behaviours in adulthood. http://medicalxpress.com/news/2012-04-physical-abuse-suicidal-thoughts.html Psychology & Psychiatry Tue, 24 Apr 2012 12:29:36 EST news254489368 Research from Queen Mary, University of London has uncovered the mechanism which causes normal cells to develop into cancer, giving hope in the fight against one of the UK's biggest killers. http://medicalxpress.com/news/2012-03-cancer-early-stages.html Cancer Mon, 26 Mar 2012 17:37:33 EST news252002236 A new finding in basic science should trigger a "change in thinking" about how cancer drugs might be developed and tested for maximum effectiveness, says Louis M. Weiner, M.D., director of the Georgetown Lombardi Comprehensive Cancer Center, in a "Clinical Implications of Basic Research" article titled Tumor-Cell Death, Autophagy, and Immunity published in the March 22 issue of the New England Journal of Medicine (NEJM). http://medicalxpress.com/news/2012-03-impact-cancer-drugs-dying-cells.html Cancer Wed, 21 Mar 2012 17:00:06 EST news251556631 Doctors and researchers of Hospital del Mar and its research institute, the IMIM, have lead a study describing a new pharmacological resistance to cancer. This new mechanism is a mutation in an oncogene called EGFR (epidermal growth factor receptor) causing resistance to treatment using a drug called cetuximab, a monoclonal antibody which specifically attacks the EGFR. http://medicalxpress.com/news/2012-01-resistance-colon-cancer-treatment.html Cancer Sun, 22 Jan 2012 13:04:32 EST news246459858 The pigmented cells called melanocytes aren't just for making freckles and tans. Melanocytes absorb ultraviolet light, protecting the skin from the harmful effects of the sun. They also are the cells that go haywire in melanoma, as well as in more common conditions as vitiligo and albinism. http://medicalxpress.com/news/2011-10-lab-made-skin-cells-aid-transplantation.html Medical research Wed, 26 Oct 2011 13:45:55 EST news238855546 Women with cancer-causing strains of human papillomavirus (HPV) may be at increased risk for cardiovascular disease (CVD) and stroke even when no conventional risk factors for CVD are present. http://medicalxpress.com/news/2011-10-hpv-linked-cardiovascular-disease-women.html Cardiology Mon, 24 Oct 2011 16:31:35 EST news238692570 A new and better understanding of blood vessel growth and vascular development (angiogenesis) in cancer has been made possible by research carried out by a team of scientists from Moffitt Cancer Center, the University of Florida, Harvard University, Yale University and the Children's Hospital of Los Angeles. http://medicalxpress.com/news/2011-09-scientists-key-molecule-blocks-abnormal.html Medical research Wed, 21 Sep 2011 13:43:55 EST news235831424 (Medical Xpress) -- A new study released this week in the Proceedings of the National Academy of Science reveals that the medication methylphenidate, best known as Ritalin, may delay puberty in males. The researchers caution that this study was performed in monkeys and more research needs to be done before it can determine possible effects on humans. http://medicalxpress.com/news/2011-09-adhd-drugs-affect-male-puberty.html Attention deficit disorders Tue, 20 Sep 2011 10:34:03 EST news235733605 Probiotics, often referred to as 'good bacteria', are known to promote a healthy gut, but can they promote a healthy mind? Exploring the new world of neurological probiotics, researchers in BioEssays present new ideas on how neurochemicals delivered directly to the gut, via probiotic intestinal microbiota, exert their beneficial effects in maintaining gastrointestinal health and even psychological well-being. http://medicalxpress.com/news/2011-07-gut-full-probiotics-neurological-well-being.html Other Wed, 06 Jul 2011 03:12:39 EST news229140750