http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. "Borreliosis" or "Lyme disease" is caused by the bacterium "Borrelia burgdorferi". In Austria approximately 16,000 people fall ill with borreliosis annually following a tick bite. Roughly every fifth tick in Austria carries the pathogen. Borreliosis can be treated effectively with antibiotics, however a prophylactic vaccination is not available. In a current multicentre study, in which the MedUni Vienna participated, the reliable effectiveness of a possible vaccine against borreliosis has now been proved. http://medicalxpress.com/news/2013-05-effective-vaccination-borreliosis.html Diseases, Conditions, Syndromes Tue, 14 May 2013 08:53:29 EST news287740400 Within the past decade, the variability in pharmacodynamic response and moderate antiplatelet efficacy of clopidogrel has raised major concerns, in particular because it is associated with an increased risk for ischemic events in PCI patients. Certainly, the public should have detailed knowledge about the incidence of high on-treatment platelet reactivity (HTPR) and its impact on clinical outcomes. http://medicalxpress.com/news/2013-05-under-recognised-under-treated-prothrombotic-condition-high.html Cardiology Mon, 06 May 2013 08:28:47 EST news287047719 Mining the records of routine interactions between patients and their care providers can detect drug side effects a couple of years before an official alert from the U.S. Food and Drug Administration, a Stanford University School of Medicine study has found. http://medicalxpress.com/news/2013-04-clinical-yield-early-drug-reactions.html Medications Wed, 10 Apr 2013 14:59:58 EST news284824729 An independent panel of experts, including an academic from Queen Mary, University of London, which was tasked by the government to make recommendations regarding drugs and driving, has published its report. http://medicalxpress.com/news/2013-03-expert-panel-drugs.html Medications Fri, 08 Mar 2013 08:50:02 EST news281953132 A novel head-to-head study looking at differences in how the antiretroviral (ARV) drug tenofovir gets absorbed in the body as either an oral tablet or a vaginal gel found tenofovir gel can achieve substantially higher concentrations of active drug in vaginal tissue than the oral tablet, suggesting that tenofovir gel should be highly effective in protecting women against HIV transmitted through vaginal sex. Yet, as unequivocal as the study's results may be, they have not been borne out in HIV prevention trials to date, leading the researchers to believe that effectiveness of tenofovir-based products depends on factors other than ARV tissue concentrations alone. http://medicalxpress.com/news/2013-01-tenofovir-gel-drug-absorption-hiv.html HIV & AIDS Wed, 30 Jan 2013 17:08:15 EST news278788086 (HealthDay)—Although use of recombinant human erythropoietin (rHuEPO) is prohibited among athletes because it reportedly enhances performance, there is no scientific evidence that it does so, according to a study published online Dec. 6 in the British Journal of Clinical Pharmacology. http://medicalxpress.com/news/2012-12-evidence-doping-athletic.html Medications Mon, 10 Dec 2012 03:44:31 EST news274333445 The drug erythropoietin, often called EPO, is banned from sports because it is believed to enhance an athlete's performance and give people who use it an unfair advantage over unenhanced competitors. However a new systemic review of existing research, published in the British Journal of Clinical Pharmacology, reveals that there is no scientific evidence that it does enhance performance, but there is evidence that using it in sport could place a user's health and life at risk. http://medicalxpress.com/news/2012-12-epo-doping-elite-evidence-benefit.html Health Wed, 05 Dec 2012 19:00:02 EST news273948343 (HealthDay)—Sustained release technologies for administering the opioid antagonist naltrexone (SRX) seem to be effective with an acceptable adverse event profile, according to a review published online Oct. 22 in the British Journal of Clinical Pharmacology. http://medicalxpress.com/news/2012-11-sustained-naltrexone-effective-safe-opioid.html Medications Thu, 01 Nov 2012 18:50:01 EST news271013800 The University of Liverpool has been awarded funding to determine whether differences in our genes determine how patients respond to drugs used to treat Tuberculosis (TB) in Sub-Saharan Africa. http://medicalxpress.com/news/2012-10-scientists-role-genes-tuberculosis.html Genetics Thu, 25 Oct 2012 11:40:13 EST news270383337 Drugs prescribed to treat anxiety, depression and insomnia may increase patients' risk of being involved in motor vehicle accidents, according to a recent study, published in the British Journal of Clinical Pharmacology. Based on the findings, the researchers suggested doctors should consider advising patients not to drive while taking these drugs. http://medicalxpress.com/news/2012-09-antidepressants-pills-anxiety-drugs.html Medications Wed, 12 Sep 2012 19:00:01 EST news266688694 (Medical Xpress)—Scientists at the University of Liverpool and the Royal Liverpool University Hospital have been awarded £1.4 million to design a new drug for the treatment of chronic pain. http://medicalxpress.com/news/2012-08-drug-chronic-pain.html Medical research Fri, 24 Aug 2012 09:40:01 EST news265018693 (HealthDay) -- Duloxetine appears safe for the routine clinical care of women with stress urinary incontinence (SUI), according to a study published online July 23 in the British Journal of Clinical Pharmacology. http://medicalxpress.com/news/2012-07-low-dose-duloxetine-deemed-safe-urinary.html Diseases, Conditions, Syndromes Fri, 27 Jul 2012 15:16:11 EST news262620957 (Medical Xpress) -- A commonly prescribed medicine used to treat conditions such as heart failure and hypertension does not present women over 55 with any increased risk of breast cancer, a new study at the University of Dundee has shown. http://medicalxpress.com/news/2012-07-hypertension-drug-breast-cancer-women.html Medications Mon, 23 Jul 2012 07:24:58 EST news262247091 (HealthDay) -- A reduction in central to brachial amplification induced by some antihypertensive drugs may result in lesser reductions in central than brachial systolic blood pressure, according to research published online May 25 in the British Journal of Clinical Pharmacology. http://medicalxpress.com/news/2012-06-anti-htn-drugs-distinct-effect-central.html Medical research Wed, 06 Jun 2012 14:10:01 EST news258208003 (HealthDay) -- The American Society of Clinical Oncology Clinical Practice Guideline on Appropriate Chemotherapy Dosing for Obese Adult Patients With Cancer recommends using full weight-based cytotoxic chemotherapy doses to treat obese patients with cancer, according to an overview published online April 2 in the Journal of Clinical Oncology. http://medicalxpress.com/news/2012-04-full-weight-based-chemo-doses-obese.html Cancer Fri, 06 Apr 2012 04:29:32 EST news252905362 (HealthDay) -- Pregnant women taking the antidepressants known as selective serotonin reuptake inhibitors (SSRIs) face a slightly increased risk of developing dangerously high blood pressure, Canadian researchers report. http://medicalxpress.com/news/2012-03-antidepressants-pregnancy-complication.html Medications Fri, 23 Mar 2012 05:34:52 EST news251699684 Smokers planning to kick the habit may have more success if they begin using a cessation medication several weeks before they actually try to quit. Those are the results of a clinical trial conducted by researchers at the University at Buffalo Roswell Park Cancer Institute (RPCI) and other institutions published recently in Clinical Pharmacology and Therapeutics. http://medicalxpress.com/news/2012-01-cessation-medication-earlier-easier.html Addiction Thu, 05 Jan 2012 10:59:03 EST news244983534 New research from the University of North Carolina at Chapel Hill schools of medicine and pharmacy may help explain the failure of some recent clinical trials of prevention of HIV infection, compared to the success of others that used the same drugs. http://medicalxpress.com/news/2011-12-prophecy-success-hiv-clinical-trials.html HIV & AIDS Wed, 07 Dec 2011 14:25:29 EST news242490246 Repeatedly taking slightly too much paracetamol over time can cause a dangerous overdose that is difficult to spot, but puts the person at danger of dying. Patients may not come to hospital reporting the overdose, but because they feel unwell. This clinical situation needs to be recognized and treated rapidly because these patients are at even greater danger than people who take single overdoses. http://medicalxpress.com/news/2011-11-paracetamol-ingestion-slightly-fatal-.html Medications Wed, 23 Nov 2011 04:02:47 EST news241243137 New technology now makes it possible to collect 'near real-time' data about whether people are having any side effects from vaccination. By studying people who received the 2009-10 swine flu vaccination in Scotland, researchers showed that this rapid reporting can add another layer of safety to future vaccination campaigns. In addition, the data collected revealed no significant safety issues in patients exposed to the vaccine. The project's report has just been published in the British Journal of Clinical Pharmacology. http://medicalxpress.com/news/2011-11-hi-tech-survey-vaccination.html Medications Tue, 15 Nov 2011 03:45:23 EST news240551114 Some compounds found in grapes help to protect skin cells from the sun's ultraviolet radiation, according to a study by researchers from the University of Barcelona and the CSIC (Spanish National Research Council). The study supports the use of grapes or grape derivatives in sun protection products. http://medicalxpress.com/news/2011-07-grapes-ultraviolet.html Health Fri, 29 Jul 2011 10:30:43 EST news231154235 Giving amphetamines to adults with Attention Deficit Hyperactivity Disorder (ADHD) can help them control their symptoms, but the side effects mean that some people do not manage to take them for very long. These conclusions were drawn by a team of five researchers working at Girona and Barcelona Universities in Spain, and published in a new Cochrane Systematic Review. http://medicalxpress.com/news/2011-07-short-term-amphetamines-adhd-symptoms-adults.html Psychology & Psychiatry Wed, 27 Jul 2011 10:40:03 EST news230981148