http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. (Medical Xpress)—A little more than a year after the FDA approved Kalydeco (Vx-770), the first drug of its kind to treat the underlying cause of cystic fibrosis, University of Missouri researchers believe they have found exactly how this drug works and how to improve its effectiveness in the future. Described in the current issue of the Proceedings of the National Academy of Sciences, MU researchers have redefined a key regulatory process in the defective protein responsible for cystic fibrosis that could change the way scientists approach the lethal genetic disease. http://medicalxpress.com/news/2013-03-discovery-efficacy-cystic-fibrosis-drug.html Medical research Thu, 21 Mar 2013 14:21:27 EST news283094460 Cystic fibrosis is one of the most common inherited single gene diseases, with an incidence of 1 out of 3,000 newborns in central Europe. An EU study developed a novel gene therapy approach for improving fluid absorption in diseased airways. http://medicalxpress.com/news/2012-09-therapy-airway-hydration-status-cystic.html Diseases, Conditions, Syndromes Thu, 20 Sep 2012 09:00:01 EST news267348408 A recent study led by Gergely Lukacs, a professor at McGill University's Faculty of Medicine, Department of Physiology, and published in the January issue of Cell, has shown that restoring normal function to the mutant gene product responsible for cystic fibrosis (CF) requires correcting two distinct structural defects. This finding could point to more effective therapeutic strategies for CF in the future. http://medicalxpress.com/news/2012-03-roadmap-effective-drug-discovery-cystic.html Medical research Mon, 12 Mar 2012 11:14:23 EST news250769655 The Lung Institute of WA (LIWA) has recently made a breakthrough in the search for a drug to improve the quality of life of patients with Cystic Fibrosis (CF). http://medicalxpress.com/news/2011-11-cystic-fibrosis-drug-reverses-genetic.html Medical research Mon, 28 Nov 2011 07:56:44 EST news241689382 Contrary to expectations that the neurotransmitter GABA only inhibited neuronal firing in the adult brain, RIKEN-led research has shown that it can also excite interneurons in the hippocampus of the rat brain by changing the conductance of ions across the membranes of these cells. http://medicalxpress.com/news/2011-11-neurons.html Neuroscience Fri, 25 Nov 2011 10:47:23 EST news241440417 In a breakthrough, researchers at the International Center for Materials Nanoarchitectonics (MANA, Japan) demonstrate for the first time the key features in the neuroscience and psychology of memory by a AgS2 synapse. http://medicalxpress.com/news/2011-09-atomic-nano-switches-emulate-human-memory.html Medical research Thu, 15 Sep 2011 13:16:28 EST news235311377 Researchers have identified an unconventional path that may correct the defect underlying cystic fibrosis, according to a report in the September 2nd issue of the journal Cell. This new treatment dramatically extends the lives of mice carrying the disease-associated mutation. http://medicalxpress.com/news/2011-09-unconventional-path-cystic-fibrosis.html Medical research Thu, 01 Sep 2011 12:46:52 EST news234099944