http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. (Medical Xpress)—Doctor Joel Weinstock, a parasitologist at Tufts Medical Center in a commentary piece published in the journal Nature, describes work that he and colleagues have been involved in that focuses on studying the possibility of introducing parasitic worms into the guts of patients suffering from autoimmune diseases such as Crohn's disease. The thinking he says, is that modern hygienic lifestyles may be contributing to such diseases and that reintroducing parasitic worms and perhaps certain bacteria into the gut may restore a natural balance in the gut and relieve patients of such symptoms as chronic diarrhea, bleeding and infections. http://medicalxpress.com/news/2012-11-parasitologist-espouses-parasitic-worms-treatment.html Immunology Thu, 08 Nov 2012 06:00:01 EST news271574652 (Medical Xpress)—A new study in mice has shown that genetically engineered bacteria can protect against inflammatory bowel disease (IBD), which includes a host of conditions including ulcerative colitis and Crohn's disease. http://medicalxpress.com/news/2012-11-genetically-bacteria-crohn-colitis.html Medical research Fri, 02 Nov 2012 05:30:02 EST news271050191 Patients newly diagnosed with pediatric Crohn's disease had significantly different levels of certain types of bacteria in their intestinal tracts than age-matched controls, according to a paper in the October Journal of Clinical Microbiology. The work may ultimately lead to treatment involving manipulation of the intestinal bacteria. http://medicalxpress.com/news/2012-10-specific-bacterial-species-crohn.html Diseases, Conditions, Syndromes Mon, 22 Oct 2012 14:32:13 EST news270135115 Teamwork between a pair of transcription factors may be responsible for regulating the functioning of Th17 cells, which when found in excessive amounts are believed to play a major role in many autoimmune diseases, according to a study published last week in the journal Science by a national team of researchers. http://medicalxpress.com/news/2012-09-molecular-pathways-involved-autoimmune-diseases.html Immunology Fri, 28 Sep 2012 08:26:12 EST news268039560 A research team led by investigators at New York University and NYU School of Medicine has determined how cells that cause inflammatory ailments, such as Crohn's disease, multiple sclerosis, and arthritis, differentiate from stem cells and ultimately affect the clinical outcome of these diseases. http://medicalxpress.com/news/2012-09-inflammatory-cells-function-stage-future.html Inflammatory disorders Wed, 26 Sep 2012 13:24:34 EST news267884658 (Medical Xpress)—Michigan State University researchers have unlocked secrets in bone marrow that could lead to improved treatments for colitis and Crohn's disease. http://medicalxpress.com/news/2012-09-bone-marrow-secrets-colitis-crohn.html Medical research Mon, 24 Sep 2012 16:37:01 EST news267723389 (HealthDay)—Use of certain antibiotics may put children at higher risk for developing bowel diseases, new research has found. http://medicalxpress.com/news/2012-09-antibiotics-childhood-bowel-disease.html Pediatrics Mon, 24 Sep 2012 11:59:08 EST news267706740 New research shows that a special population of stem cells found in cord blood has the innate ability to migrate to the intestine and contribute to the cell population there, suggesting the cells' potential to treat inflammatory bowel disease (IBD). http://medicalxpress.com/news/2012-09-cell-therapy-bowel-disease.html Diseases, Conditions, Syndromes Wed, 19 Sep 2012 15:53:24 EST news267288796 A common bacteria ever-present on the human skin and previously considered harmless, may, in fact, be the culprit behind chronic sinusitis, a painful, recurring swelling of the sinuses that strikes more than one in ten Americans each year, according to a study by scientists at the University of California, San Francisco. http://medicalxpress.com/news/2012-09-links-sinusitis-microbial-diversity-approach.html Diseases, Conditions, Syndromes Wed, 12 Sep 2012 14:00:01 EST news266675084 What if a key factor ultimately behind a cancer was not a genetic defect but ecological? http://medicalxpress.com/news/2012-08-genes-coli-bacteria-linked-colon.html Cancer Thu, 16 Aug 2012 14:00:10 EST news264343202 Adalimumab (an anti-tumor necrosis factor [TNF] antibody) is effective in maintaining remission in certain pediatric patients with Crohn's disease, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association. http://medicalxpress.com/news/2012-08-adalimumab-therapy-children-crohn-disease.html Diseases, Conditions, Syndromes Mon, 06 Aug 2012 12:40:14 EST news263475592 A fatty membrane in the belly called the omentum has until recently been considered somewhat like the appendix -- it didn't seem to serve much purpose. http://medicalxpress.com/news/2012-06-belly-fat-isnt-bad-fatty.html Immunology Wed, 06 Jun 2012 17:00:32 EST news258217448 (Medical Xpress) -- Measuring bone age should be a standard practice of care for pediatric patients with Crohn’s disease, in order to properly interpret growth status and improve treatment, according to a new study from the UCSF Benioff Children’s Hospital.   http://medicalxpress.com/news/2012-05-routine-crohn-disease-children-bone.html Inflammatory disorders Fri, 25 May 2012 08:17:53 EST news257152654 (HealthDay) -- The food additive maltodextrin, commonly used in some artificial sweeteners, may worsen Crohn's disease by encouraging the growth of E. coli bacteria in the small intestine, a new study suggests. http://medicalxpress.com/news/2012-05-compound-artificial-sweeteners-worsen-crohn.html Diseases, Conditions, Syndromes Mon, 21 May 2012 15:40:01 EST news256829921 A large-scale study of medical claims data shows that introducing sophisticated biologic therapies early in the course of treatment for Crohn's disease improves response to medication and reduces the need for surgery. http://medicalxpress.com/news/2012-04-early-introduction-biologic-therapy-crohn.html Inflammatory disorders Tue, 17 Apr 2012 13:14:32 EST news253887260 Researchers from the Hotchkiss Brain Institute (HBI) and the Snyder Institute for Chronic Diseases at the University of Calgary's Faculty of Medicine have discovered a pathway that may contribute to the symptoms related to Crohn's disease and ulcerative colitis, collectively known as Inflammatory Bowel Disease (IBD). This research is a major milestone in developing future drug therapies for those living with these debilitating disorders. http://medicalxpress.com/news/2012-03-crohn-disease.html Inflammatory disorders Wed, 21 Mar 2012 09:22:39 EST news251540547 Several clinical trials at the University of Cincinnati (UC) are focused on potential treatments for two serious gastroenterological illnesses—Crohn’s disease and Clostridium difficile, or C. difficile. http://medicalxpress.com/news/2012-03-clinical-trials-focus-treatments-crohn.html Diseases, Conditions, Syndromes Tue, 20 Mar 2012 10:04:25 EST news251456546 The Nutritional Immunology and Molecular Medicine Laboratory (NIMML) research team at Virginia Tech has discovered important new information on the efficacy of conjugated linoleic acid (CLA) in treating Crohn's disease, a form of inflammatory bowel disease (IBD). CLA is a naturally occurring acid found in meat and dairy products known for its anti-cancer and immune modulatory properties. http://medicalxpress.com/news/2012-03-therapy-crohn-disease.html Inflammatory disorders Mon, 19 Mar 2012 11:55:48 EST news251376933 In the largest study of its kind, researchers from Mount Sinai School of Medicine have discovered five new genetic mutations associated with Crohn's disease in Jews of Eastern European descent, also known as Ashkenazi Jews. The findings, which appear in the March 8 online edition of PLoS Genetics, are the first step in an attempt to explain why the prevalence of Crohn's disease is nearly four times higher in Ashkenazi Jews than in other populations. http://medicalxpress.com/news/2012-03-genetic-variations-crohn-disease-ashkenazi.html Genetics Thu, 08 Mar 2012 17:00:08 EST news250444201 The team of researchers from the Universities of Bristol, Queensland. Oxford, Texas and Toronto, used a technique called genome-wide association where millions of genetic markers are measured in thousands of people that have the disease and thousands of healthy individuals. http://medicalxpress.com/news/2011-07-genetic-auto-immune-arthritis.html Genetics Sun, 10 Jul 2011 13:01:17 EST news229516172 A new study from Rhode Island Hospital has found that MR enterography (MRE) without the use of an anti-peristaltic agent were as reliable as CT enterography (CTE) in determining the presence of Crohn's disease. Additionally, MRE reduces the patient's exposure to ionizing radiation. The study is now published online in advance of print in the European Journal of Radiology. http://medicalxpress.com/news/2011-06-enterography-effective-ct-crohn-disease.html Other Wed, 15 Jun 2011 11:04:06 EST news227354347 (Medical Xpress) -- Researchers at the University of Toronto have discovered the role the interactions between key proteins plays in the body’s response to Crohn’s Disease - a revelation that may lead to the development of new therapies for patients. http://medicalxpress.com/news/2011-06-role-key-proteins-crohn-disease.html Medical research Tue, 14 Jun 2011 07:45:34 EST news227256286 A protein isolated from beneficial bacteria found in yogurt and dairy products could offer a new, oral therapeutic option for inflammatory bowel disorders (IBD), suggests a study led by Vanderbilt University Medical Center researcher Fang Yan, M.D., Ph.D. http://medicalxpress.com/news/2011-05-protein-probiotic-bacteria-alleviate-inflammatory.html Medical research Mon, 23 May 2011 12:24:53 EST news225372267 Naltrexone reduced inflammation in Crohn's patients in a research study at Penn State College of Medicine. http://medicalxpress.com/news/2011-05-naltrexone-inflammation-crohn-patients.html Diseases, Conditions, Syndromes Thu, 19 May 2011 09:56:40 EST news225017754 University of Minnesota Medical School researchers have discovered a method to quickly and exponentially grow regulatory T-cells – also known as "suppressor cells." The new process enables replication of the cells by tens of millions in several weeks, a dramatic increase over previous duplication methods. Historically, regulatory T-cells have been difficult to replicate. http://medicalxpress.com/news/2011-05-duplicating-immunity-boosting-regulatory-t-cells.html Medical research Wed, 18 May 2011 14:00:01 EST news224942164 Adalimumab (ADA), a drug often prescribed for women with Crohn's disease, actively crosses the placenta during the final trimester of pregnancy and remains in a newborn's bloodstream for at least three months, researchers at the University of California San Francisco have found. http://medicalxpress.com/news/2011-05-adalimumab-cord-blood-infants-exposed.html Medications Sun, 08 May 2011 06:26:03 EST news224054725