https://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Fifteen prescription medications, including Botox and the diabetes drug Trulicity, will be the focus of federal price negotiations that could lower prices for Medicare patients. https://medicalxpress.com/news/2026-01-medicare-prices-botox-major-drugs.html Thu, 29 Jan 2026 19:10:03 EST news688914594 Analyzing patient health care notes recorded during millions of medical appointments at GPs and hospitals across England has allowed researchers at the London School of Hygiene & Tropical Medicine (LSHTM) to map the entire spectrum of diseases linked to atopic eczema for the first time. https://medicalxpress.com/news/2026-01-nhs-patient-diseases-linked-eczema.html Mon, 19 Jan 2026 12:38:41 EST news688048681 Psychologist Melissa Hunt and gastroenterologist Chung Sang Tse and colleagues have found that cognitive behavioral therapy reduced disability for patients with Crohn's disease and ulcerative colitis and that psychologists with no prior gastrointestinal experience could learn to deliver this therapy effectively. https://medicalxpress.com/news/2025-12-psychological-impacts-inflammatory-bowel-disease.html Thu, 18 Dec 2025 10:08:25 EST news685274881 Researchers at UT Southwestern Medical Center have identified a protein that causes human cell membranes to break open in a form of inflammatory programmed cell death called necroptosis. Their findings, reported in Nature, could eventually lead to new treatments for a broad array of conditions that involve this phenomenon, including severe infections and sepsis, chronic inflammatory diseases such as Crohn's disease, neurodegenerative diseases such as Alzheimer's and amyotrophic lateral sclerosis (ALS), and several forms of cancer. https://medicalxpress.com/news/2025-12-key-protein-necroptotic-cell-death.html Wed, 10 Dec 2025 13:06:51 EST news684594241 The American Gastroenterological Association (AGA) has released a comprehensively updated clinical guideline on the pharmacological management of moderate-to-severe Crohn's disease. The new guideline uses cutting-edge network meta-analyses to recommend prescribing medications based on patients' prior treatments for moderate-to-severe Crohn's disease. https://medicalxpress.com/news/2025-11-crohn-disease-treatment-guidance-therapies.html Thu, 20 Nov 2025 05:00:03 EST news682701586 A research group has revealed that transcription factors RUNX2 and BHLHE40 play crucial roles in inducing T cells involved in Crohn's disease. Crohn's disease is an intractable disorder characterized by chronic inflammation in the digestive tract. Tissue-resident memory T cells (TRM), which persist long-term in the intestinal mucosa, have been implicated in disease pathogenesis, but it has not been clear how these cells are induced. https://medicalxpress.com/news/2025-09-key-transcription-factors-crohn-disease.html Thu, 04 Sep 2025 12:33:03 EDT news676207981 The human body is a complex and interconnected system, where alterations caused by one disease can promote the onset of others. This tendency for certain diseases to occur together, beyond what would be expected by chance, is called co-occurrence. Thus, although there are diseases with widely known co-occurrence in certain groups of patients, such as Crohn's disease and the development of ulcers, many of the molecular mechanisms that would explain them were, until now, unknown. https://medicalxpress.com/news/2025-09-molecular-reveals-previously-hidden-diseases.html Tue, 02 Sep 2025 11:40:04 EDT news676032001 Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered why smoking tobacco helps people suffering from ulcerative colitis, a chronic disease typified by inflammation of the large intestine. https://medicalxpress.com/news/2025-08-mouth-gut-bacteria-migration-good.html Mon, 25 Aug 2025 13:09:55 EDT news675346190 Inflammatory bowel disease, or IBD, is an umbrella term for a group of chronic conditions that cause inflammation and swelling in the digestive tract. It primarily includes two conditions: ulcerative colitis and Crohn's disease. While both involve inflammation, they affect different parts of the gastrointestinal (GI) tract and behave differently over time. https://medicalxpress.com/news/2025-08-ibd-diagnosis.html Sun, 24 Aug 2025 09:40:02 EDT news675067169 About 2.7 million people in the U.S. live with inflammatory bowel diseases, which cause long-term inflammation in the digestive system. The number of children diagnosed with these conditions, like Crohn's disease, is rising faster than in adults, but the reasons for the increase are puzzling. https://medicalxpress.com/news/2025-07-potential-disease-specific-signatures-pediatric.html Tue, 29 Jul 2025 07:34:05 EDT news672993242 Crohn's disease is a serious inflammatory bowel disease (IBD) that impacts millions worldwide. The disease is chronic and highly unpredictable, manifesting symptoms such as abdominal pain, diarrhea—sometimes with blood—and severe fatigue. The inflammation can also cause narrow sections in the intestines and create channels from the intestines to other organs, known as fistulas. https://medicalxpress.com/news/2025-07-crohn-disease-outlook-brightens-early.html Mon, 07 Jul 2025 12:56:49 EDT news671111806 Up to half of patients with Crohn's disease, an inflammatory bowel disease, develop a complication called fibrosis, where the gut becomes scarred and obstructed, causing pain and bloating. Currently, the only treatment option for these gut "strictures" is surgery. https://medicalxpress.com/news/2025-06-spatial-reveals-network-cells-genes.html Wed, 25 Jun 2025 14:46:04 EDT news670081561 Chronic inflammatory bowel diseases (IBD), such as Crohn's disease and ulcerative colitis, cause recurring diarrhea, fever, pain, and significant psychological distress. Despite major advances and modern medications, treatment remains challenging. Only a subset of patients responds to medication. https://medicalxpress.com/news/2025-06-gut-energy-crisis-metabolism-severely.html Fri, 06 Jun 2025 12:19:19 EDT news668431154 Chronic inflammatory bowel disease is challenging to treat and carries a risk of complications, including the development of bowel cancer. Young people are particularly affected: when genetic predisposition and certain factors coincide, diseases such as ulcerative colitis or Crohn's disease usually manifest between the ages of 15 and 29—a critical period for education and early career development. Prompt diagnosis and treatment are crucial. https://medicalxpress.com/news/2025-05-therapeutic-chronic-gut-inflammation-cancer.html Fri, 30 May 2025 11:04:05 EDT news667821841 Researchers and clinicians have developed major new guidelines for the monitoring of patients with inflammatory bowel disease (IBD) to prevent them going on to develop bowel cancer. https://medicalxpress.com/news/2025-05-guidelines-ibd-patients-bowel-cancer.html Thu, 01 May 2025 07:59:04 EDT news665305142 A research team led by Mount Sinai has uncovered mechanisms of abnormal immune cell function that may lead to Crohn's disease, according to findings published in Science Immunology. The researchers said their discovery provides a better understanding of disease development and could inform the development and design of new therapies to prevent inflammation before it starts in the chronic disorder. https://medicalxpress.com/news/2025-03-immune-cell-dysfunction-gi-tract.html Fri, 21 Mar 2025 14:00:03 EDT news661688401 People with Crohn's disease and related joint inflammation linked to immune system dysfunction have distinct gut bacteria or microbiota, with the bacterium Mediterraneibacter gnavus being a potential biomarker, according to new study by Weill Cornell Medicine researchers. https://medicalxpress.com/news/2025-03-biomarker-crohn-disease-arthritis.html Wed, 05 Mar 2025 13:08:03 EST news660402481 Crohn's disease, a debilitating inflammatory bowel disease, has many known contributing factors, including bacterial changes in the microbiome that foster an inflammatory environment. Now, for the first time, Crohn's disease has been tied to a virus—specifically, the Epstein-Barr virus (EBV), best known for causing infectious mononucleosis (mono). https://medicalxpress.com/news/2025-03-reveals-link-crohn-disease-epstein.html Mon, 03 Mar 2025 14:53:04 EST news660235982 Specialists from the Digestive System Department at Hospital Germans Trias have conducted and published a unique study that represents a significant improvement in the monitoring and treatment of patients who have undergone surgery due to one of the main inflammatory bowel diseases: Crohn's disease. https://medicalxpress.com/news/2025-02-colonoscopies-patients-crohn-disease.html Thu, 27 Feb 2025 15:33:03 EST news659892781 A surgical approach pioneered in Ireland could have a global impact on the treatment of Crohn's disease. https://medicalxpress.com/news/2025-02-surgical-approach-significant-impact-treatment.html Tue, 18 Feb 2025 13:06:33 EST news659106390 Researchers at the University of Gothenburg have uncovered a critical mechanism that may pave the way for innovative treatments for Crohn's disease. Their findings center on repairing the protective barrier of the gut to slow disease progression. https://medicalxpress.com/news/2025-02-boosting-gut-barrier-crohn-disease.html Tue, 18 Feb 2025 12:00:03 EST news659102401 A special liquid diet, known as exclusive enteral nutrition, is an essential therapy for Crohn's disease. Patients consume only this formula for six to eight weeks, completely avoiding solid foods. However, the exact reasons why this is helpful were previously unclear. https://medicalxpress.com/news/2025-02-microbiome-shift-linked-crohn-disease.html Tue, 11 Feb 2025 14:24:04 EST news658506241 A study by Michigan Medicine researchers has investigated possible genetic factors for drug efficacy for children with Crohn's disease. https://medicalxpress.com/news/2025-02-anti-tnf-drugs-dont-kids.html Mon, 10 Feb 2025 15:58:36 EST news658425512 People with the skin condition psoriasis often have invisible inflammation in the small intestine with an increased propensity for "leaky gut," according to new research at Uppsala University. These changes in the gut could explain why psoriasis sufferers often have gastrointestinal problems and are more prone to developing Crohn's disease. https://medicalxpress.com/news/2025-01-inflammation-stomach-problems-psoriasis.html Mon, 20 Jan 2025 16:00:50 EST news656611247 The U.S. Food and Drug Administration has approved Eli Lilly's Omvoh (mirikizumab-mrkz) for the treatment of moderately to severely active Crohn's disease in adults. https://medicalxpress.com/news/2025-01-fda-omvoh-moderately-severely-crohn.html Fri, 17 Jan 2025 07:50:01 EST news656321536 A study by University of Michigan researchers may provide an explanation for why some patients with Crohn's disease continue to experience symptoms, even in the absence of inflammation. https://medicalxpress.com/news/2024-12-potential-culprit-lingering-crohn-disease.html Fri, 20 Dec 2024 12:02:04 EST news653918522 Crohn's disease, a type of chronic inflammatory bowel disease (IBD), often causes scar-like tissue to build up in the intestines, termed fibrosis. Over time, increased scar tissue builds up in the intestinal walls, causing them to narrow and preventing waste from leaving the body. Most patients with Crohn's disease will need to undergo surgery to treat or prevent life-threatening bowel obstructions and infections. https://medicalxpress.com/news/2024-12-key-driver-fibrosis-crohn-disease.html Wed, 18 Dec 2024 16:36:04 EST news653762161 Inflammatory bowel diseases (IBDs), including Crohn's disease and ulcerative colitis, are marked by cycles of immune activation and inflammation that significantly impact patients' lives. https://medicalxpress.com/news/2024-12-clock-role-circadian-inflammatory-bowel.html Thu, 12 Dec 2024 08:38:33 EST news653215109 Inflammatory bowel disease (IBD) is a chronic inflammation of the digestive tract. It includes conditions such as ulcerative colitis and Crohn's disease. People with IBD may experience persistent symptoms like frequent diarrhea, weight loss, abdominal pain and fatigue. https://medicalxpress.com/news/2024-12-diet-inflammatory-bowel-disease.html Wed, 04 Dec 2024 06:38:22 EST news652516695 Scientists at Örebro University have identified specific protein patterns in blood tests that can predict inflammatory bowel disease (IBD) up to 16 years before diagnosis. In particular, Crohn's disease can be detected with very high accuracy. The study has been published in Gastroenterology. https://medicalxpress.com/news/2024-11-inflammatory-bowel-disease-blood-samples.html Tue, 26 Nov 2024 15:36:04 EST news651857762