http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. (Medical Xpress)—Researchers from Queen Mary, University of London, and Barts Health NHS Trust have identified the genetic mutation behind a devastating disease of the small intestine. http://medicalxpress.com/news/2013-01-scientists-genetic-mutation-rare-disease.html Genetics Fri, 04 Jan 2013 07:25:47 EST news276506729 The compound licofelone inhibited oral cancer growth by inhibiting the cyclooxygenase and 5-lipoxygenase pathways, with no observable side effects, according to data from a rat study presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research, held here Oct. 16-19, 2012. http://medicalxpress.com/news/2012-10-compound-dual-action-inhibits-oral.html Cancer Fri, 19 Oct 2012 07:34:48 EST news269850881 To relieve pain, arthritis sufferers are prescribed medications that may include non-steroidal anti-inflammatory drugs (NSAIDs) or cyclooxygenase-2 (COX-2) inhibitors, both of which can irritate the digestive tract. At times additional drugs are co-prescribed with NSAIDs or COX-2 inhibitors to prevent adverse gastrointestinal (GI) effects. Now a new study available today in the American College of Rheumatology journal, Arthritis & Rheumatism, reveals that decreasing gastroprotective agent (GPA) adherence among users of COX-2 inhibitors is linked to an increased risk of such upper GI complications. http://medicalxpress.com/news/2012-04-gastroprotective-drugs-anti-inflammatory-medicines.html Arthritis & Rheumatism Mon, 16 Apr 2012 03:57:14 EST news253766693 Nicolas G. Bazan, MD, Ph.D, Boyd Professor and Director of the Neuroscience Center of Excellence at LSU Health Sciences Center New Orleans, and David Stark, an MD/Ph.D student working in his lab, have discovered how a key chemical neurotransmitter that interacts with two receptors in the brain promotes either normal function or a disease process -- determining whether brain cells live or die. The work is published and highlighted in the September 28, 2011 issue of the Journal of Neuroscience. http://medicalxpress.com/news/2011-09-key-survival-brain-cells.html Neuroscience Wed, 28 Sep 2011 16:37:30 EST news236446640 The anti-inflammatory drug celecoxib, known by the brand name Celebrex, triggers liver cancer cell death by reacting with a protein in a way that makes those cells commit suicide, according to a new study. http://medicalxpress.com/news/2011-05-common-anti-inflammatory-coaxes-liver-cancer.html Cancer Mon, 16 May 2011 11:40:01 EST news224761706