http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. A new video protocol in Journal of Visualized Experiments (JoVE) details an assay to identify brain tumor initiating stem cells from primary brain tumors. Through flow cytometry, scientists separate stem cells from the rest of the tumor, allowing quick and efficient analysis of target cells. This approach has been effectively used to identify similar stem cells in leukemia patients. http://medicalxpress.com/news/2012-09-isolate-stem-cells-brain-tumors.html Medical research Tue, 25 Sep 2012 13:22:40 EST news267798153 Research published Aug. 1 by scientists at Cold Spring Harbor Laboratory (CSHL) links gene mutations found in some patients with Meier-Gorlin syndrome (MGS) with specific cellular dysfunctions that are thought to give rise to a particularly extreme version of dwarfism, small brain size, and other manifestations of abnormal growth which generally characterize that rare condition. http://medicalxpress.com/news/2012-07-protein-involved-dna-replication-centrosome.html Genetics Tue, 31 Jul 2012 17:30:39 EST news262974631 The development of more effective cancer drugs could be a step nearer thanks to the discovery, by scientists at Warwick Medical School, of how an inbuilt 'security check' operates to guarantee cells divide with the correct number of chromosomes. http://medicalxpress.com/news/2012-04-warwick-scientists-uncover-checkpoint-proteins.html Cancer Fri, 20 Apr 2012 11:18:25 EST news254139485 Methicillin resistant staph aureus (MRSA) infections are resistant to antibiotics and can cause a myriad of problems -- bone erosion, or osteomyelitis, which shorten the effective life of an implant and greatly hinder replacement of that implant. MRSA can result in prolonged disability, amputation and even death. http://medicalxpress.com/news/2012-02-immunization-mrsa-horizon.html Diseases, Conditions, Syndromes Tue, 14 Feb 2012 16:37:01 EST news248459752 They are the Robinson Crusoes of the intracellular world -- lone chromosomes, whole and hardy, stranded outside the nucleus where their fellow chromosomes reside. Such castaways, each confined to its own "micronucleus," are often found in cancer cells, but scientists haven't known what role, if any, they play in the cancer process. http://medicalxpress.com/news/2012-01-pulverized-chromosomes-linked-cancer.html Cancer Thu, 19 Jan 2012 17:00:07 EST news246214800 (PhysOrg.com) -- When it comes to the body's blood supply, maintaining the right balance is crucial. UCLA stem cell scientists have now discovered that in the common fruit fly, this balancing act requires a complex "conversation" involving more parties than originally thought. http://medicalxpress.com/news/2012-01-blood-cells-progenitors-critical.html Medical research Thu, 05 Jan 2012 07:02:10 EST news244967157 A new study led by Harvard School of Public (HSPH) researchers provides a novel explanation as to why some tuberculosis cells are inherently more difficult to treat with antibiotics. The discovery, which showed that the ways mycobacteria cells divide and grow determine their susceptibility to treatment with drugs, could lead to new avenues of drug development that better target tuberculosis cells. http://medicalxpress.com/news/2011-12-uncovers-evidence-drug-resistant-tuberculosis-cells.html Medical research Thu, 15 Dec 2011 14:00:17 EST news243178940 Steve Reiner, MD, professor of Medicine, and Burton Barnett, a doctoral student in the Reiner lab at the Perelman School of Medicine at the University of Pennsylvania, have shown how immune cells, called B lymphocytes, are able to produce daughter cells that are not equal, a finding that might explain how lifelong antibodies are made after vaccination. http://medicalxpress.com/news/2011-12-cells-antibodies-vaccination.html Medical research Thu, 15 Dec 2011 14:00:13 EST news243178420 Suppressing a newly identified and characterized protein involved in regulating cell division could be a novel strategy to fight certain cancers because it stops the malignant cells from dividing and causes them to die quickly, according to a study by researchers with UCLA's Jonsson Comprehensive Cancer Center. http://medicalxpress.com/news/2011-12-suppression-protein-critical-cell-division.html Cancer Fri, 09 Dec 2011 09:32:00 EST news242645511 Each time a cell divides -- and it takes millions of cell divisions to create a fully grown human body from a single fertilized cell -- its chromosomes have to be accurately divvied up between both daughter cells. Researchers at the Stowers Institute for Medical Research used, ironically enough, the single-celled organism Saccharomyces cerevisiae -- commonly known as baker's yeast -- to gain new insight into the process by which chromosomes are physically segregated during cell division. http://medicalxpress.com/news/2011-11-gain-insight-chromosome.html Genetics Thu, 17 Nov 2011 18:40:02 EST news240774017 Scientists at Warwick Medical School have uncovered the molecular process of how cells are by-passing the body's inbuilt 'health checkpoint' with cells that carry unequal numbers of chromosomes that have a higher risk of developing cancer. http://medicalxpress.com/news/2011-11-scientists-daughter-cells-chromosomes.html Genetics Tue, 01 Nov 2011 11:30:03 EST news239365794 When cells divide normally, DNA gets copied perfectly and distributed among the daughter cells with an even hand. Occasionally though, DNA breaks during division and is rearranged, resulting in duplications or deletions of important parts of the blueprint. http://medicalxpress.com/news/2011-10-genomic-architecture-presages-instability.html Genetics Sun, 02 Oct 2011 13:00:02 EST news236778645 A novel technique that enables scientists to measure and document tumor-inducing changes in DNA is providing new insight into the earliest events involved in the formation of leukemias, lymphomas and sarcomas, and could potentially lead to the discovery of ways to stop those events. http://medicalxpress.com/news/2011-09-technique-events-tumor.html Cancer Thu, 29 Sep 2011 13:27:18 EST news236521626