http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Scientists from the Icahn School of Medicine at Mount Sinai, in collaboration with researchers from Icelandic Heart Association, Sage Bionetworks, and other institutions, have discovered that a network of genes involved in the inflammatory response in the brain is a crucial mechanism driving Late Onset Alzheimer's Disease (LOAD). The findings, published online today in the journal Cell, provide new understanding of key pathways and genes involved in LOAD and valuable insights to develop potential therapies for the disease. http://medicalxpress.com/news/2013-04-key-mechanism-common-alzheimer-disease.html Alzheimer's disease & dementia Thu, 25 Apr 2013 12:00:04 EST news286108563 Biotech pioneer Amgen Inc., in a bid for a big edge in using people's genetic information to find better ways to attack diseases, is buying human genetics research and analytics leader deCODE Genetics for $415 million. http://medicalxpress.com/news/2012-12-amgen-decode-genetics-million.html Genetics Mon, 10 Dec 2012 13:41:16 EST news274369261 Humans inherit more than three times as many mutations from their fathers as from their mothers, and mutation rates increase with the father's age but not the mother's, researchers have found in the largest study of human genetic mutations to date. http://medicalxpress.com/news/2012-08-mutations-dad.html Genetics Fri, 24 Aug 2012 10:18:52 EST news265022314 Do older fathers doom their children to genetic disease? http://medicalxpress.com/news/2012-08-children-older-men-gene-abnormalities.html Genetics Wed, 22 Aug 2012 13:52:19 EST news264862325 deCODE Genetics, together with their colleagues from the pharmaceutical company Genentech, reported today in the journal Nature the discovery of a variant of the amyloid precursor protein (APP) gene that confers protection against both Alzheimer's disease (AD) and cognitive decline in the elderly. The findings also indicate a linkage between age-related cognitive decline and late-onset forms of AD, the most common cause of dementia. http://medicalxpress.com/news/2012-07-natural-alzheimers-disease.html Alzheimer's disease & dementia Wed, 11 Jul 2012 17:18:33 EST news261245882 Patients see potential benefits from direct-to-consumer genetic testing, but are also concerned about how test results will be used, and generally are unwilling to pay more than $10 or $20 for them, according to focus groups conducted by researchers at Loyola University Chicago Stritch School of Medicine. http://medicalxpress.com/news/2012-05-patients-benefits-direct-to-consumer-genetics.html Genetics Thu, 10 May 2012 14:53:21 EST news255880394 Scientists at deCODE Genetics and academic collaborators from Iceland, The Netherlands, Spain, Denmark, Germany, Sweden, the USA, the UK and Romania today report the discovery of a variant in the sequence of the human genome associated with risk of developing basal cell carcinoma of the skin (BCC), as well as prostate cancer and glioma, the most serious form of brain cancer. The study was done in collaboration with Illumina, Inc., and is published today in the online edition of Nature Genetics. http://medicalxpress.com/news/2011-09-genetic-factor-skin-prostate-brain.html Genetics Sun, 25 Sep 2011 17:15:41 EST news236187587