http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Most ovarian cancer patients are diagnosed with late stage disease that is unresponsive to existing therapies. In a new study, researchers from the Perelman School of Medicine at the University of Pennsylvania School of Medicine show that a two-step personalized immunotherapy treatment—a dendritic cell vaccine using patients' own tumor followed by adoptive T cell therapy—triggers anti-tumor immune responses in these type of patients. Four of the six patients treated in the trial responded to the therapy, the investigators report this month in OncoImmunology. http://medicalxpress.com/news/2013-01-two-step-immunotherapy-advanced-ovarian-cancer.html Cancer Thu, 31 Jan 2013 16:25:16 EST news278871796 UC Irvine oncologists are looking for new ways to treat glioblastoma multiforme, the deadliest type of brain cancer. While surgery followed by chemotherapy and radiation is the current standard of care, it doesn't fully eliminate the cancer. The goal is to develop an additional therapy that seeks out and destroys the cancer cells that inevitably remain. http://medicalxpress.com/news/2012-11-brain-cancer-breakthrough-experimental-vaccine.html Cancer Wed, 14 Nov 2012 08:22:21 EST news272103731 (Medical Xpress) -- Researchers from the Perelman School of Medicine at the University of Pennsylvania are in the midst of testing a personalized, dendritic cell vaccine in patients with recurrent ovarian, primary peritoneal or fallopian tube cancer – a group of patients who typically have few treatment options. Now, they have shown they can shorten the time to manufacture this type of anti-cancer vaccine, which reduces costs of manufacturing the treatment while still yielding powerful dendritic cells that may be beneficial for these and a variety of other tumor types. The data is published in the December issue of PLoS ONE. http://medicalxpress.com/news/2011-12-shorten-personalized-ovarian-cancer-vaccine.html Cancer Mon, 26 Dec 2011 07:01:24 EST news244105188