http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Women with high blood pressure during pregnancy have an increased risk of high blood pressure even 40 years after maternity, which leads in turn to an increased risk of cardiovascular disease. This has been demonstrated by researchers at Sahlgrenska Academy, University of Gothenburg, Sweden. http://medicalxpress.com/news/2013-04-cardiovascular-disease-pregnant-women-high.html Cardiology Mon, 15 Apr 2013 11:35:41 EST news285244532 (Medical Xpress)—A Phase 2 clinical trial testing a new protocol for treating a relatively rare form of brain cancer, primary CNS lymphoma, may change the standard of care for this disease, according to doctors at UC San Francisco who led the research. http://medicalxpress.com/news/2013-04-brain-cancer-treatment-effective-toxic.html Cancer Tue, 09 Apr 2013 07:17:49 EST news284710655 Vitamin D deficiency may decrease kidney function in transplant recipients, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The finding suggests that vitamin D supplementation may help improve the health of kidney transplant recipients. http://medicalxpress.com/news/2013-03-vitamin-d-linked-kidney-function.html Other Thu, 28 Mar 2013 17:00:02 EST news283707576 A study in the JAMA Neurology (formerly the Archives of Neurology) suggests that controlling or preventing risk factors such as hypertension earlier in life may limit or delay the brain changes associated with Alzheimer's disease and other age-related neurological deterioration. http://medicalxpress.com/news/2013-03-uncontrolled-hypertension-alzheimer-disease.html Alzheimer's disease & dementia Mon, 18 Mar 2013 18:36:24 EST news282850567 (HealthDay)—Women with type 1 diabetes experience post-pregnancy deterioration in glycemic control and sustained weight gain, according to research published online Dec. 18 in Diabetes Care. http://medicalxpress.com/news/2013-02-post-pregnancy-deterioration-glycemic-t1dm.html Health Thu, 14 Feb 2013 11:53:41 EST news280065192 (Medical Xpress)—Multiple sclerosis, a brain disease that affects over 400,000 Americans, causes movement difficulties and many neurologic symptoms. MS has two key elements: The nerves that direct muscular movement lose their electrical insulation (the myelin sheath) and cannot transmit signals as effectively. And many of the long nerve fibers, called axons, degenerate. http://medicalxpress.com/news/2013-02-view-ms-unexpectedly-nerve-fibers.html Neuroscience Wed, 06 Feb 2013 10:14:01 EST news279368035 Spending many hours in centre-based child care does not lead to more aggression and disobedience in children, according to a new study using data from the Norwegian Mother and Child Cohort Study (MoBa). http://medicalxpress.com/news/2013-01-centre-based-child-hours-aggression-disobedience.html Pediatrics Tue, 29 Jan 2013 08:39:28 EST news278671160 (HealthDay)—Adult patients with acute pulmonary embolism (PE) with elevated plasma lactate levels are at a high risk of death and adverse outcomes, regardless of whether they also present with shock or hypotension; right-sided ventricular dysfunction; or elevation of troponin I, according to research published online Jan. 9 in the Annals of Emergency Medicine. http://medicalxpress.com/news/2013-01-death-pe-patients-high-plasma.html Diseases, Conditions, Syndromes Thu, 24 Jan 2013 18:30:05 EST news278272632 An Australian scientist said Wednesday he had discovered a way to turn the HIV virus against itself in human cells in the laboratory, in an important advance in the quest for an AIDS cure. http://medicalxpress.com/news/2013-01-australian-potential-aids.html HIV & AIDS Wed, 16 Jan 2013 05:36:02 EST news277536956 The physical benefits of regular exercise and remaining physically active, especially as we age, are well documented. However, it appears that it is not only the body which benefits from exercise, but the mind too. The evidence for this is published in a new review by Hayley Guiney and Liana Machado from the University of Otago, New Zealand, which focuses on the importance of physical activity in keeping and potentially improving cognitive function throughout life. http://medicalxpress.com/news/2012-12-aerobic-boosts-brain-power.html Psychology & Psychiatry Thu, 13 Dec 2012 10:45:23 EST news274617916 (Medical Xpress)—High rates of self-harm and mental distress among asylum seekers in long-term detention has renewed calls for the review of Australia's offshore processing. http://medicalxpress.com/news/2012-12-free-vulnerable-offshore-detention.html Psychology & Psychiatry Mon, 10 Dec 2012 06:56:48 EST news274344993 A large population- and health systems-based prospective study reports earlier discussions about end of life (EOL) care preferences are strongly associated with less aggressive care in the last days of life and increased use of hospice care for patients with advanced cancer. The study, published November 13 in the Journal of Clinical Oncology, provides the first-of-its –kind scientific evidence that timing of EOL care discussions affects decisions about EOL care. http://medicalxpress.com/news/2012-11-earlier-life-discussions-linked-aggressive.html Cancer Tue, 13 Nov 2012 13:58:33 EST news272037501 Over the last 15 years, researchers have found a significant association between vascular diseases such as hypertension, atherosclerosis, diabetes type 2, hyperlipidemia, and heart disease and an increased risk of Alzheimer's disease. In a special issue of the Journal of Alzheimer's Disease, leading experts provide a comprehensive overview of the pathological, biochemical, and physiological processes that contribute to Alzheimer's disease risk and ways that may delay or reverse these age-related abnormalities. http://medicalxpress.com/news/2012-11-vascular-disease-key-prevalence-alzheimer.html Alzheimer's disease & dementia Mon, 05 Nov 2012 16:45:12 EST news271356276 Research led by Chu Chen, PhD, Associate Professor of Neuroscience at LSU Health Sciences Center New Orleans, has identified an enzyme called Monoacylglycerol lipase (MAGL) as a new therapeutic target to treat or prevent Alzheimer's disease. The study was published online November 1, 2012 in the Online Now section of the journal Cell Reports. http://medicalxpress.com/news/2012-11-therapeutic-alzheimer-disease.html Alzheimer's disease & dementia Thu, 01 Nov 2012 14:29:10 EST news270998935 As men and women age, increasing quantities of fat tissue inevitably take up residence in skeletal muscle. A small study of older and younger men conducted at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University suggests that a build-up of a fat molecule known as ceramide might play a leading role in muscle deterioration in older adults. The results of the study were published online this month by the Journal of Applied Physiology, a publication of the American Physiological Society. http://medicalxpress.com/news/2012-10-fat-molecule-ceramide-factor-muscle.html Medical research Wed, 31 Oct 2012 16:20:00 EST news270919182 New research presented in October at the 6th Neurodegenerative Conditions Research and Development Conference in San Francisco demonstrates the role of the investigational compound IRX4204 in alleviating cognitive decline in animal models of Alzheimer's disease (AD). The presentation entitled "Investigation of the RXR-specific agonist IRX4204 as a Disease Modifying Agent of Alzheimer's Disease Neuropathology and Cognitive Impairment" was made by lead researcher Giulio Maria Pasinetti, MD, PhD, of the Mount Sinai School of Medicine in New York City. http://medicalxpress.com/news/2012-10-drug-animal-alzheimer-parkinson-dementia.html Alzheimer's disease & dementia Fri, 26 Oct 2012 14:10:01 EST news270475571 Can you bite into an apple? If so, you are more likely to maintain mental abilities, according to new research from Karolinska Institutet in Sweden. http://medicalxpress.com/news/2012-10-ability-linked-dementia.html Alzheimer's disease & dementia Thu, 04 Oct 2012 10:25:49 EST news268565126 Fertility treatment has a strong emotional impact on women who want to have children. A study of European countries with the highest number of assisted reproduction cycles identifies which aspects of reproduction treatment contribute to psychological stress. http://medicalxpress.com/news/2012-10-treatment-stress-women-fertility-therapy.html Health Wed, 03 Oct 2012 11:19:52 EST news268481979 (Medical Xpress)—Women with Alzheimer's show worse mental deterioration than men with the disease, even when at the same stage of the condition, according to researchers from the University of Hertfordshire. http://medicalxpress.com/news/2012-08-women-alzheimer-deteriorate-faster-men.html Alzheimer's disease & dementia Fri, 24 Aug 2012 11:55:08 EST news265028017 Patients with Alzheimer's disease who suffered episodes of delirium while hospitalized had a sharply increased rate of mental decline for up to five years after being hospitalized compared to those who did not have any such episodes, according to a study by researchers at The Institute for Aging Research at Hebrew SeniorLife, an affiliate of Harvard Medical School. http://medicalxpress.com/news/2012-08-links-delirium-long-term-cognitive-decline.html Alzheimer's disease & dementia Mon, 20 Aug 2012 16:00:06 EST news264692331 (HealthDay) -- Evidence is building that poor sleep patterns may do more than make you cranky: The amount and quality of shuteye you get could be linked to mental deterioration and Alzheimer's disease, four new studies suggest. http://medicalxpress.com/news/2012-07-poor-age-brain.html Health Mon, 16 Jul 2012 17:29:50 EST news261678185 In a paper published in the July 11 online issue of Science Translational Medicine, researchers at the University of California, San Diego School of Medicine have identified two key regulatory proteins critical to clearing away misfolded proteins that accumulate and cause the progressive, deadly neurodegeneration of Huntington's disease (HD). http://medicalxpress.com/news/2012-07-proteins-clearer-huntington-disease.html Neuroscience Wed, 11 Jul 2012 14:00:01 EST news261230666 Researchers at the Translational Genomics Research Institute (TGen) have developed a method of isolating biospecimens that could lead to a less costly, less invasive and more accurate way of diagnosing chronic kidney disease, or CKD. http://medicalxpress.com/news/2012-07-tgen-method-isolates-biospecimens-treatment.html Diseases, Conditions, Syndromes Wed, 11 Jul 2012 09:46:06 EST news261218753 Scientists from the University of South Florida and Fudan University in Shanghai found increases in brain volume and improvements on tests of memory and thinking in Chinese seniors who practiced Tai Chi three times a week, reports an article published today in the Journal of Alzheimer's Disease. http://medicalxpress.com/news/2012-06-tai-chi-brain-size-benefits.html Health Tue, 19 Jun 2012 13:06:24 EST news259329829 (Medical Xpress) -- Cachexia, a syndrome characterized by rapid weight loss and muscle deterioration, is a major cause of death among patients suffering from diseases like cancer, AIDS and chronic infection. In fact, 30 per cent of cancer-related deaths are the result of cachexia-induced muscle loss rather than the primary malignancy. And while scientists are making strides in gaining a better understanding of this deadly condition, no effective anti-cachectic therapies exist to date. However, a newly published study by McGill University researchers shows that a low dose of Pateamine A (PatA) is effective at preventing cancer-induced muscle wasting – findings that could someday point to the development of cachexia-fighting drugs. http://medicalxpress.com/news/2012-06-tool-combat-cachexia-induced-muscle.html Medical research Wed, 13 Jun 2012 07:30:01 EST news258790639 Two studies by neurological researchers at Rush University Medical Center suggest that, in the future, colonic tissue obtained during either colonoscopy or flexible sigmoidoscopy may be used to predict who will develop Parkinson's disease, a neurodegenerative disorder of aging that that leads to progressive deterioration of motor function due to loss of neurons in the brain that produce dopamine, a neurotransmitter essential to executing movement. http://medicalxpress.com/news/2012-05-colonoscopy-flexible-sigmoidoscopy-parkinson.html Parkinson's & Movement disorders Tue, 15 May 2012 15:00:01 EST news256299941 Mount Sinai School of Medicine researchers have succeeded in developing a biosynthetic polyphenol that improves cognitive function in mice with Alzheimer's disease (AD). The findings, published in a recent issue of the Journal of Neuroscience, provide insight in determining the feasibility of biosynthetic polyphenols as a possible therapy for AD in humans, a progressive neurodegenerative disease for which there is currently no cure. http://medicalxpress.com/news/2012-05-biosynthetic-grape-derived-compound-alzheimer-disease.html Alzheimer's disease & dementia Thu, 03 May 2012 03:40:01 EST news255232671 (Medical Xpress) -- New research from Queen Mary, University of London in collaboration with research groups in the USA sheds light on why gum disease can become more common with old age. http://medicalxpress.com/news/2012-04-hints-gums-age.html Immunology Tue, 17 Apr 2012 09:30:03 EST news253873591 Cardiomyopathy comprises a deterioration of the heart muscle that affects the organ's ability to efficiently pump blood through the body. Previously researchers have tied forms of the disease to the alternative splicing of titin, a giant protein that determines the structure and biomechanical properties of the heart, but the molecular mechanism remained unknown. http://medicalxpress.com/news/2012-04-scientists-elucidate-molecular-mechanism-contributing.html Cardiology Sun, 01 Apr 2012 13:00:07 EST news252494529 A recent study by National University of Singapore (NUS) researchers revealed that Asian breast cancer patients who had received or were undergoing chemotherapy treatment showed symptoms of "chemobrain", in which they encounter memory loss, difficulty in decision making and speech problems. http://medicalxpress.com/news/2012-03-asian-breast-cancer-survivors-cognitive.html Cancer Thu, 15 Mar 2012 09:50:02 EST news251023796