http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Evidence has shown that green tea extract may be an effective herbal remedy useful for weight control and helping to regulate glucose in type 2 diabetes. In order to ascertain whether green tea truly has this potential, Jae-Hyung Park and his colleagues from the Keimyung University School of Medicine in the Republic of Korea conducted a study, now published in the Springer journal Naunyn-Schmedeberg's Archives of Pharmacology. http://medicalxpress.com/news/2013-04-green-tea-weight.html Overweight and Obesity Mon, 29 Apr 2013 12:03:06 EST news286455774 For the first time, researchers have shown that poorly controlled maternal diabetes has an adverse effect on methylation of the maternal imprinting gene Peg3, contributing to impaired development in offspring. http://medicalxpress.com/news/2013-03-maternal-diabetes-impairs-methylation-imprinted.html Diabetes Wed, 20 Mar 2013 15:57:55 EST news283013853 Julien Diana and Yannick Simoni of the "Immune Mechanisms in Type 1 Diabetes," Inserm/Université Paris Descartes, directed by Agnès Lehuen, have just published the results of their work on type 1 diabetes in the Nature Medicine journal. http://medicalxpress.com/news/2012-12-role-innate-immune-cells-diabetes.html Diabetes Wed, 19 Dec 2012 11:42:08 EST news275139717 Researchers in Singapore have succeeded in tracking, for the first time, the molecular changes caused by type 2 diabetes that affect how the body handles glucose production in the liver. In a series of experiments in mice, the researchers introduced a form of the compound pyruvate that incorporated specially treated carbon nuclei. This allowed the researchers to follow the processing of the compound using magnetic resonance spectroscopy (MRS). In this way, the team, led by Phillip Lee of the Singapore Bioimaging Consortium, showed that the enzyme pyruvate carboxylase plays a key role in the development of diabetes. http://medicalxpress.com/news/2012-12-ability-molecular-diabetes-personalized-medicine.html Diabetes Wed, 19 Dec 2012 09:31:51 EST news275131897 A new therapeutic approach to diabetes that combines insulin and an inhibitor of the epidermal growth factor (EGF) betacellulin could limit the progression of diabetic macular edema (DME), Cleveland Clinic researcher Bela Anand-Apte, MD, PhD, said at the American Society for Cell Biology Annual Meeting, on Dec. 17 in San Francisco. http://medicalxpress.com/news/2012-12-insulin-growth-factor-inhibitor-limits.html Diabetes Mon, 17 Dec 2012 18:00:01 EST news274986876 In a study in mice, scientists at Karolinska Institutet in Sweden have discovered a new potential therapy that may reduce brain damage following stroke in type 2 diabetic patients. The suggested drug is already approved for the treatment of type 2 diabetes. However, the scientists hope that this new results, presented in the scientific journal Diabetes, also opens up the possibility to decrease brain injury after stroke in other patient groups with a high stroke risk. http://medicalxpress.com/news/2012-12-diabetes-drug-brain.html Diabetes Mon, 03 Dec 2012 19:00:01 EST news273758427 Delayed wound healing is a major complication of diabetes because the physiological changes in tissues and cells impair the wound healing process. This can result in additional disease outcomes such as diabetic foot ulcer, a significant cause of morbidity in the growing population of diabetic patients. A new study has found that topically applied simvastatin accelerates wound healing in diabetic mice, suggesting important implications for humans with diabetes. This study is published in the December issue of The American Journal of Pathology. http://medicalxpress.com/news/2012-11-topical-simvastatin-shown-wound-diabetes.html Diabetes Tue, 27 Nov 2012 12:50:55 EST news273243030 Researchers have studied the suitability of Abelmoschus Esculentus (AE) as complementary or as an alternative approach to treat diabetics. http://medicalxpress.com/news/2012-11-okra-natural-alternative-method-diabetes.html Diabetes Fri, 02 Nov 2012 11:26:37 EST news271074372 Growing evidence suggests that there may be a link between diabetes and Alzheimer's disease, but the physiological mechanisms by which diabetes impacts brain function and cognition are not fully understood. In a new study published in Aging Cell, researchers at the Salk Institute for Biological Studies show, for the first time, that diabetes enhances the development of aging features that may underlie early pathological events in Alzheimer's. http://medicalxpress.com/news/2012-10-diabetes-proteins-linked-alzheimer-features.html Alzheimer's disease & dementia Fri, 26 Oct 2012 09:42:42 EST news270463247 Researchers have discovered a new therapeutic target for diabetic nephropathy, the leading cause of kidney failure. The findings, appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN), could help protect the kidney health of individuals with diabetes. http://medicalxpress.com/news/2012-10-diabetic-kidney-disease-failure.html Diseases, Conditions, Syndromes Thu, 18 Oct 2012 17:00:01 EST news269791201 (Medical Xpress)—Work by Michigan Technological University biologist Xiaoqing Tang is yielding new insights into how a tiny snippet of genetic material can promote healthy insulin production in mice. http://medicalxpress.com/news/2012-09-microrna-derails-protein-blocks-insulin.html Medical research Thu, 20 Sep 2012 07:40:01 EST news267343343 Diabetic nephropathy is one of the most serious complications related to diabetes, often leading to end-stage kidney disease. Purple corn grown in Peru and Chile is a relative of blue corn, which is readily available in the U.S. The maize is rich in anthocyanins (also known as flavonoids), which are reported to have anti-diabetic properties. Scientists from the Department of Food and Nutrition and Department of Biochemistry at Hallym University in Korea investigated the cellular and molecular activity of purple corn anthocyanins (PCA) to determine whether and how it affects the development of diabetic nephropathy (DN). Their findings suggest that PCA inhibits multiple pathways involved in the development of DN, which may help in developing therapies aimed at type 2 diabetes and kidney disease. http://medicalxpress.com/news/2012-09-purple-corn-compound-aid-future.html Medical research Tue, 18 Sep 2012 17:22:15 EST news267207727 Technion researchers have built pancreatic tissue with insulin-secreting cells, surrounded by a three-dimensional network of blood vessels. The engineered tissue could pave the way for improved tissue transplants to treat diabetes. http://medicalxpress.com/news/2012-08-pancreatic-tissues-transplants-diabetics.html Diabetes Wed, 15 Aug 2012 09:04:42 EST news264239032 Research to be presented at the Annual Meeting of the Society for the Study of Ingestive Behavior (SSIB), the foremost society for research into all aspects of eating and drinking behavior, finds that gastric bypass surgery induces changes in the gut microbiota and peptide release that are similar to those seen after treatment with prebiotics. http://medicalxpress.com/news/2012-07-gastric-bypass-surgery-gut-microbiota.html Surgery Tue, 10 Jul 2012 04:47:30 EST news261114401 In their extraordinary quest to decode human metabolism, researchers at the Salk Institute for Biological Studies have discovered a pair of molecules that regulates the liver's production of glucose -- the simple sugar that is the source of energy in human cells and the central player in diabetes. http://medicalxpress.com/news/2012-04-molecular-liver-glucose-production-ii.html Medical research Sun, 08 Apr 2012 13:00:29 EST news253084650 A class of compounds found in hops, the crop generally known for its role in beer production, reduces weight gain in obese and diabetic mice, according to a study published Mar. 28 in the open access journal PLoS ONE. http://medicalxpress.com/news/2012-03-compounds-health-obese-diabetic-mice.html Diabetes Wed, 28 Mar 2012 17:00:13 EST news252153740 (Medical Xpress) -- Researchers at Genetech Inc. in South San Francisco, California, led by molecular biologist Junichiro Sonoda, have discovered that a single injection of antibodies into obese diabetic mice provided a marked and sustained improvement in their condition and a reduction in their weight. http://medicalxpress.com/news/2011-12-antibody-diabetes-obesity.html Medical research Fri, 16 Dec 2011 06:00:01 EST news243233160 The enzyme arginase-2 plays a major role in kidney failure, and blocking the action of this enzyme might lead to protection against renal disease in diabetes, according to researchers. http://medicalxpress.com/news/2011-11-aims-diabetic-kidney-failure.html Diseases, Conditions, Syndromes Sat, 05 Nov 2011 04:20:05 EST news239682697 Researchers at Washington University School of Medicine in St. Louis have restored normal blood sugar metabolism in diabetic mice using a compound the body makes naturally. The finding suggests that it may one day be possible for people to take the compound much like a daily vitamin as a way to treat or even prevent type 2 diabetes. http://medicalxpress.com/news/2011-10-natural-compound-reverse-diabetes-mice.html Medical research Tue, 04 Oct 2011 13:40:01 EST news236952643 Researchers at the John G. Rangos Sr. Research Center at Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine have identified a powerful molecular pathway that regulates the liver's management of insulin and new glucose production, which could lead to new therapies for diabetes. The findings were published online this week in Diabetes, a journal of the American Diabetes Association. http://medicalxpress.com/news/2011-09-team-key-protein-excess-liver.html Medical research Wed, 28 Sep 2011 12:09:46 EST news236430573 Controlling diabetes may someday involve mining stem cells from the lining of the uterus, Yale School of Medicine researchers report in a new study published in the journal Molecular Therapy. The team treated diabetes in mice by converting cells from the uterine lining into insulin-producing cells. http://medicalxpress.com/news/2011-09-scientists-uterine-stem-cells-diabetes.html Medical research Wed, 14 Sep 2011 13:26:08 EST news235225549 (Medical Xpress) -- Our liver could be a major springboard for determining life-changing diabetes diagnosis and treatment thanks to a world-first discovery by an Australian-Chinese research team. http://medicalxpress.com/news/2011-06-liver-key-diabetes.html Medical research Wed, 15 Jun 2011 06:40:01 EST news227335903 An experimental cure for Type 1 diabetes has a nearly 80 percent success rate in curing diabetic mice. The results, to be presented Saturday at The Endocrine Society's 93rd Annual Meeting in Boston, offer possible hope of curing a disease that affects 3 million Americans. http://medicalxpress.com/news/2011-06-gene-therapy-reverses-diabetes-mice.html Medical research Mon, 06 Jun 2011 09:53:19 EST news226572254 University of Louisville researchers have replicated the inflammatory gene changes of a human kidney as it progresses from mild to severe diabetic nephropathy, using a mouse model developed by a UofL researcher, according to an article published today in the journal Experimental Nephrology. Diabetic nephropathy is the foremost cause of kidney failure. http://medicalxpress.com/news/2011-05-replicate-human-kidney-gene-mouse.html Medical research Mon, 23 May 2011 11:20:24 EST news225368416