http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Combination treatment with everolimus, an inhibitor of the mammalian target rapamycin (mTOR), and octreotide has shown to improve progression-free survival for patients with advanced neuroendocrine tumors and a history of carcinoid syndrome, according to researchers at The University of Texas MD Anderson Cancer Center. http://medicalxpress.com/news/2011-11-everolimus-prolongs-progression-free-survival-patients.html Cancer Tue, 29 Nov 2011 14:50:01 EST news241799710 Younger patients with diffuse large B-cell lymphoma given a more intensive regimen of chemotherapy combined with rituximab survive significantly longer, and are approximately twice as likely to remain in remission 3 years later, compared with patients given standard chemotherapy treatment plus rituximab, according to an article published Online First in the Lancet. http://medicalxpress.com/news/2011-11-intensive-chemotherapy-recurrence-survival-younger.html Cancer Thu, 24 Nov 2011 18:30:03 EST news241362774 Sluggish recycling of a protein-slicing enzyme could promote Alzheimer's disease, according to a study published online on November 21 in The Journal of Cell Biology. http://medicalxpress.com/news/2011-11-poor-recycling-bace1-enzyme-alzheimer.html Medical research Mon, 21 Nov 2011 12:00:03 EST news241097829 In sub-Saharan Africa, couples in long-term relationships where one partner is HIV-positive and the other is HIV-negative (HIV serodiscordant couples) could benefit from anti-AIDS drugs (antiretroviral therapy) given either as treatment or as a prevention measure (prophylaxis) to reduce the risk of HIV transmission. These findings, from a modelling study led by Timothy Hallett from Imperial College London and published in this week's PLoS Medicine, also show that this strategy could be cost-effective. http://medicalxpress.com/news/2011-11-options-couples-partner-hiv-positive.html HIV & AIDS Tue, 15 Nov 2011 18:00:02 EST news240602393 In some kidney diseases, patients have high blood levels of a protein that blocks blood vessel repair, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). Inhibiting the protein may reduce patients' risk of developing kidney failure. http://medicalxpress.com/news/2011-10-kidney-disease-patients-blood-vessels.html Diseases, Conditions, Syndromes Thu, 27 Oct 2011 17:32:51 EST news238955564 A new analysis has found that coughing may signal trouble for patients with the lung-scarring disease known as idiopathic pulmonary fibrosis. The study, published in the journal Respirology, found that patients with the condition who also cough are more likely to develop advanced forms of the disease that may be life threatening. http://medicalxpress.com/news/2011-10-danger-patients-lung-scarring-disease.html Diseases, Conditions, Syndromes Tue, 18 Oct 2011 13:27:51 EST news238163143 (Medical Xpress) -- Research by biologists at the University of York and Hull York Medical School has revealed important new information about the way the brain is affected by age. http://medicalxpress.com/news/2011-10-aging-effect-brain.html Neuroscience Mon, 10 Oct 2011 15:00:13 EST news237465613 Melanoma of the eye (ocular or uveal melanoma) frequently spreads to the liver and, once this has happened, there is no effective treatment and patients die within an average of two to four months. Only about one in ten patients live for a year. Now, final results from a phase III study have demonstrated that a new treatment significantly extends the time patients can live without the disease progressing. http://medicalxpress.com/news/2011-09-infusing-chemotherapy-liver-extra-months.html Cancer Fri, 23 Sep 2011 18:48:47 EST news236022479 UCLA researchers demonstrated that an over-the-counter dietary supplement may help inhibit development of insulin resistance and glucose intolerance, conditions that are involved in the development of Type 2 diabetes and metabolic syndrome, which affect millions worldwide. http://medicalxpress.com/news/2011-09-early-dietary-supplement-diabetes.html Diseases, Conditions, Syndromes Thu, 22 Sep 2011 17:38:02 EST news235931866 Phytoestrogens are plant compounds which, in the human body, can attach to the receptors for the female sexual hormone estrogen and which are taken in with our daily diet. A number of findings have attributed a cancer protective effect to these plant hormones. At DKFZ (Germany), a team headed by Prof. Dr. Jenny Chang-Claude summarized the results of several studies in a meta-analysis last year and showed that a diet rich in phytoestrogens lowers the risk of developing breast cancer after menopause. Now the Heidelberg researchers wanted to find out whether phytoestrogens also have an influence on the course of breast cancer. Prior investigations on this topic had provided contradictory results. http://medicalxpress.com/news/2011-09-compound-breast-cancer-mortality.html Cancer Tue, 13 Sep 2011 13:27:54 EST news235139226 Patients with ALK-rearranged non-small cell lung cancer (NSCLC) responded significantly better to pemetrexed (brand name: Alimta) than patients whose cancer did not show ALK translocation, according to research published in the September issue of the Journal of Thoracic Oncology, the official publication of the International Association for the Study of Lung Cancer (IASLC). http://medicalxpress.com/news/2011-09-lung-cancer-alk-rearrangement-pemetrexed.html Cancer Thu, 01 Sep 2011 10:42:14 EST news234092515 Children with only mildly to moderately impaired kidney function experience poor growth, delays in puberty, and heart problems, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (JASN). Therapies for these conditions might help slow the progression of kidney disease in children. http://medicalxpress.com/news/2011-08-poor-growth-puberty-heart-problems.html Diseases, Conditions, Syndromes Fri, 12 Aug 2011 15:25:14 EST news232381487 Patients suffering REM sleep behaviour disorders dream nightmares in which they are attacked and pursued, with the particularity that they express them by screaming, crying, punching and kicking while sleeping. Lancet Neurology has published the third consecutive work in five years about the relationship between this disorder and Parkinson's disease. http://medicalxpress.com/news/2011-07-rem-behavior-disorder-factor-parkinson.html Parkinson's & Movement disorders Fri, 29 Jul 2011 13:40:01 EST news231163274 Chronic non-communicable diseases (NCD), such as cardiovascular disease, diabetes, arthritis, chronic respiratory disorders and cancer represent the major global health problem of the 21st century and affect all age groups. The cost of treating these diseases is substantial, and for many countries is an under-appreciated cause of poverty. http://medicalxpress.com/news/2011-07-science-medicine-treatment-chronic-disease.html Genetics Wed, 06 Jul 2011 03:17:03 EST news229141008 A single gene is central in the development of several forms of polycystic kidney and liver disease, Yale School of Medicine researchers report in the June 19 issue of Nature Genetics. http://medicalxpress.com/news/2011-06-gene-polycystic-disease.html Genetics Sun, 19 Jun 2011 13:02:04 EST news227707307 Researchers in the School of Biomedical Sciences at The University of Queensland (UQ) have made a ground-breaking discovery in the study of growth hormone. http://medicalxpress.com/news/2011-06-scientists-breakthrough-growth-hormone.html Medical research Fri, 17 Jun 2011 12:25:57 EST news227532345 Metastatic prostate cancer patients who received an investigational vaccine made from their own frozen immune cells lived 10 months longer than those not treated with it, according to data being presented by researchers from the Kimmel Cancer Center at Jefferson at the 2011 American Society of Clinical Oncology annual meeting in Chicago on Saturday, June 4. http://medicalxpress.com/news/2011-06-asco-experimental-vaccine-frozen-immune.html Cancer Thu, 02 Jun 2011 15:44:44 EST news226248270 A Swedish research team partly consisting of researchers from Uppsala University followed a group of prostate cancer patients in the Nordic region for 15 years. The study found, among other things, that surgery reduces the risk that men with prostate cancer (even those with low-risk tumours) will die within 15 years. The results were published today in the New England Journal of Medicine. http://medicalxpress.com/news/2011-05-surgery-mortality-due-prostate-cancer.html Cancer Thu, 05 May 2011 10:58:20 EST news223811867 French researchers have reported the strongest proof yet that evidence of 'circulating tumor cells' found in samples of a patient's blood is strongly linked to poor outcomes such as a short time to disease progression. http://medicalxpress.com/news/2011-05-strong-evidence-prognostic-circulating-tumor.html Cancer Thu, 05 May 2011 10:06:40 EST news223808789 Two multi-gene tests designed to predict the risk of disease progression and response to chemotherapy in breast cancer produce broadly similar results for high- and low-risk patients, but do not always agree in their predictions for those at intermediate risk, a new analysis shows. http://medicalxpress.com/news/2011-05-breast-cancer-multi-gene.html Cancer Thu, 05 May 2011 09:56:03 EST news223808141 Researchers from Mount Sinai School of Medicine will present several key studies at the American Academy of Neurology (AAN) annual meeting, including research providing critical insight into the prognosis and clinical treatment course of people with a certain subtype of Multiple Sclerosis (MS). The meeting is taking place April 9-16 in Honolulu. http://medicalxpress.com/news/2011-04-mount-sinai-critical-ms-american.html Neuroscience Thu, 14 Apr 2011 10:08:46 EST news221994517