http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Two novel radiolabeled small molecules targeting prostate-specific membrane antigen (PSMA) have excellent potential for further development as diagnostic and therapeutic radiopharmaceuticals, according to research published this month in The Journal of Nuclear Medicine. The imaging agents—123I-MIP-1072 and 123I-MIP-1095—were shown to have a high sensitivity of lesion detection in bone, soft tissue and the prostate gland with minimal retention in non-target tissue. http://medicalxpress.com/news/2013-03-small-molecules-visualize-prostate-cancer.html Cancer Tue, 05 Mar 2013 11:05:12 EST news281703906 A previously invincible mutation in chronic myeloid leukemia (CML) has been thwarted by an investigational drug in a phase I clinical trial reported in the current edition of The New England Journal of Medicine. http://medicalxpress.com/news/2012-11-ponatinib-resistant-chronic-myeloid-leukemia.html Cancer Wed, 28 Nov 2012 17:00:21 EST news273343855 The Feinstein Institute for Medical Research announced today the submission of a New Drug Application to the US Food and Drug Administration (FDA) for the Fluorodopa F 18 positron emission tomography (PET) scan used to diagnose parkinsonian syndromes. Earlier this year, the Feinstein Institute received FDA approval under an Expanded Access Investigational New Drug (IND) program, permitting the Feinstein Institute to receive reimbursement for the use of the diagnostic tool in clinical research studies. This was the first time the FDA approved payment for Fluorodopa F 18 PET studies in parkinsonian syndromes. http://medicalxpress.com/news/2012-11-feinstein-submission-drug-application-parkinsonian.html Parkinson's & Movement disorders Wed, 14 Nov 2012 12:57:34 EST news272120187 A critical shortage of generic drugs in the United States, particularly in cancer care, could be curbed with legislation now being hammered out by the US House and Senate, doctors said on Monday. http://medicalxpress.com/news/2012-06-legislation-aims-curb-cancer-drug.html Medications Mon, 04 Jun 2012 15:40:01 EST news258042450 US health advisers on Thursday urged regulators to approve Truvada, made by Gilead Sciences, as the first preventive pill against HIV/AIDS instead of just a treatment for infected people. http://medicalxpress.com/news/2012-05-health-advisors-mull-aids-pill.html HIV & AIDS Thu, 10 May 2012 11:29:00 EST news255868134 A new drug, MDV3100, is improving the survival rate in men with advanced prostate cancer, results of a large, phase III clinical trial show. The drug is designed to block a type of cellular receptor that drives progression of prostate cancer. Based on the strength of the data from the phase III trial, it is anticipated that the biopharmaceutical company Medivation, which licensed MDV3100, will file a new drug application with the Food and Drug Administration later this year. http://medicalxpress.com/news/2012-02-drug-survival-patients-drug-resistant-prostate.html Cancer Wed, 01 Feb 2012 03:06:15 EST news247287958 Investigators at Nationwide Children's have received a grant from the National Institutes of Health (NIH) to help move a therapy for MPS IIIB that has been shown effective in mice toward clinical trials in humans. http://medicalxpress.com/news/2011-05-nih-grant-clinical-trials-lysosomal.html Medical research Wed, 25 May 2011 12:31:20 EST news225545454