http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. (HealthDay)— A drug regimen containing two powerful antifungal medicines—amphotericin B and flucytosine—reduced the risk of dying from cryptococcal meningitis by 40 percent compared to treatment with amphotericin B alone, according to new research. http://medicalxpress.com/news/2013-04-combo-therapy-fungal-meningitis.html Diseases, Conditions, Syndromes Wed, 03 Apr 2013 18:16:52 EST news284231766 (Medical Xpress)—Aggressive drug regimens used to treat multidrug-resistant tuberculosis reduce the risk of death by about 40 percent when they include at least five drugs likely to be effective against a patient's tuberculosis strain, a retrospective study conducted amid an epidemic of multidrug-resistant tuberculosis (MDR-TB) in Peru has found. http://medicalxpress.com/news/2013-03-aggressive-regimen-mortality-drug-resistant-tb.html Diseases, Conditions, Syndromes Fri, 15 Mar 2013 06:56:21 EST news282549365 Early diagnosis and treatment with antimalarial drugs (ACTs—artemisinin based combination treatments) has been linked to a reduction in malaria in the migrant population living on the Thai-Myanmar border, despite evidence of increasing resistance to ACTs in this location, according to a study by international researchers published in this week's PLOS Medicine. http://medicalxpress.com/news/2013-03-resistance-line-anti-malarial-drugs-thai-myanmar.html Diseases, Conditions, Syndromes Tue, 05 Mar 2013 17:00:08 EST news281712880 Among pregnant women in sub-Saharan Africa, intermittent preventive therapy for malaria with 3 or more doses of the drug regimen sulfadoxine-pyrimethamine was associated with a higher birth weight and lower risk of low birth weight than the current standard 2-dose regimen, according to a review and meta-analysis of previous studies published in the February 13 issue of JAMA. http://medicalxpress.com/news/2013-02-malaria-therapy-pregnancy-outcomes-infants.html Obstetrics & gynaecology Tue, 12 Feb 2013 16:30:07 EST news279906456 Results of a Johns Hopkins study suggest that individuals with schizophrenia are significantly more likely to live longer if they take their antipsychotic drugs on schedule, avoid extremely high doses and also regularly see a mental health professional. http://medicalxpress.com/news/2012-11-antipsychotic-drugs-life-individuals-schizophrenia.html Psychology & Psychiatry Thu, 01 Nov 2012 04:38:45 EST news270963171 Abbott Laboratories said Monday that its experimental hepatitis C drug regimen cured 99 percent of patients in a midstage study with the most common and hardest-to-treat type of the disease. http://medicalxpress.com/news/2012-10-abbott-labs-hepatitis-drug.html Medications Mon, 15 Oct 2012 11:51:10 EST news269520664 (Medical Xpress)—Ongoing research at the Methodist Cancer Center could reveal whether metastatic breast cancer patients with BRCA gene mutations are particularly responsive to a drug regimen that includes Veliparib, an investigational drug believed to hamper cancer cells. http://medicalxpress.com/news/2012-09-brca1-brca2-mutation-treatment-option.html Cancer Thu, 20 Sep 2012 07:45:20 EST news267345911 For years, doctors treating those with HIV have recognized a relationship between how faithfully patients take the drugs they prescribe, and how likely the virus is to develop drug resistance. More recently, research has shown that the relationship between adherence to a drug regimen and resistance is different for each of the drugs that make up the "cocktail" used to control the disease. http://medicalxpress.com/news/2012-09-mathematical-efficient-multi-drug-therapies.html Medical research Sun, 02 Sep 2012 13:00:13 EST news265786554 A common enzyme that is easily detected in blood may predict how well patients with advanced kidney cancer will respond to a specific treatment, according to doctors at Duke Cancer Institute. http://medicalxpress.com/news/2012-08-blood-treatment-kidney-cancer.html Cancer Mon, 13 Aug 2012 16:00:08 EST news264091838 A novel approach to discover the first new tuberculosis (TB) combination drug regimen cleared a major hurdle when Phase II clinical trial results found it could kill more than 99 percent of patients' TB bacteria within two weeks and could be more effective than existing treatments, according to a study published today in the Lancet. These results add to a growing body of evidence that the new regimen could reduce treatment by more than a year for some patients. http://medicalxpress.com/news/2012-07-trial-major-milestone-tb-drugs.html Diseases, Conditions, Syndromes Mon, 23 Jul 2012 16:41:53 EST news262280507 Various trials examining the use of anti-retroviral drugs in healthy heterosexuals as a way to prevent HIV have shown drastically different results, research showed Wednesday. http://medicalxpress.com/news/2012-07-pills-hiv.html HIV & AIDS Wed, 11 Jul 2012 18:28:07 EST news261250077 The first landmark randomized clinical trial for a cardiac drug regimen in Duchenne muscular dystrophy (DMD) is testing whether earlier treatment can stop or slow down heart damage that usually kills people with the disease. http://medicalxpress.com/news/2012-06-clinical-trial-heart-drug-regimen.html Medical research Tue, 26 Jun 2012 10:32:57 EST news259925561 While immediate postexposure treatment for suspected HIV is critical, pre-exposure preventive treatment is a newer method that may be effective for people in high-risk groups, states a review of evidence published in CMAJ (Canadian Medical Association Journal). http://medicalxpress.com/news/2012-05-antiretroviral-treatment-hiv-infection-evidence.html HIV & AIDS Mon, 28 May 2012 12:00:01 EST news257414615 A hormone-depleting drug approved last year for the treatment of metastatic prostate cancer can help eliminate or nearly eliminate tumors in many patients with aggressive cancers that have yet to spread beyond the prostate, according to a clinical study to be presented at the annual meeting of the American Society of Clinical Oncology (ASCO), June 1-5, in Chicago. http://medicalxpress.com/news/2012-05-hormone-depleting-drug-localized-high-risk-prostate.html Cancer Wed, 16 May 2012 18:00:05 EST news256405573 How well people with newly diagnosed epilepsy respond to their first drug treatment may signal the likelihood that they will continue to have more seizures, according to a study published in the May 9, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology. http://medicalxpress.com/news/2012-05-response-drug-treatment-likelihood-future.html Neuroscience Wed, 09 May 2012 16:00:01 EST news255782857 Infants born to women who used the anti-HIV drug tenofovir as part of an anti-HIV drug regimen during pregnancy do not weigh less at birth and are not of shorter length than infants born to women who used anti-HIV drug regimens that do not include tenofovir during pregnancy, according to findings from a National Institutes of Health network study. However, at 1 year of age, children born to the tenofovir-treated mothers were slightly shorter and had slightly smaller head circumference—about 1 centimeter each, on average—than were infants whose mothers did not take tenofovir. http://medicalxpress.com/news/2012-05-anti-hiv-drug-pregnancy-affect-infant.html HIV & AIDS Wed, 02 May 2012 03:40:01 EST news255146465 Analysis of a drug regimen approved by the F.D.A. in 2006 for the treatment of non-small cell lung cancer (bevacizumab added to the standard chemotherapy regimen carboplatin and paclitaxel) finds Medicare insured patients age 65 years and older who received this regimen did not have improved survival compared to patients who received the standard treatment of carboplatin and paclitaxel alone, according to a study in the April 18 issue of JAMA, a theme issue on comparative effectiveness research. http://medicalxpress.com/news/2012-04-drug-regimen-treatment-non-small-cell.html Cancer Tue, 17 Apr 2012 10:51:03 EST news253878657 In a comparison of drugs to prevent blood clots after angioplasty, a three-drug regimen favored in Asia to increase anti-clotting effect was found to be as safe and effective as a double-dose two-drug treatment commonly used in high-risk patients in Western countries, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session. The Scientific Session, the premier cardiovascular medical meeting, brings cardiovascular professionals together to further advances in the field. http://medicalxpress.com/news/2012-03-drug-regimen-equal-double-dose-approach.html Cardiology Mon, 26 Mar 2012 10:30:03 EST news251975406 A global health alliance Monday unveiled plans for the first clinical tests of a new treatment regimen for tuberculosis, including for patients with resistance to existing multidrug programs. http://medicalxpress.com/news/2012-03-trial-drug-resistant-tb-treatment.html Diseases, Conditions, Syndromes Mon, 19 Mar 2012 13:55:05 EST news251384097 In March 2011, a surgical team at Brigham and Women's Hospital (BWH) performed the first full face transplantation (FFT) in the United States and went on to complete a total of three FFTs this year. Now, in the first research publication to evaluate FFT in the US, and largest series worldwide, the researchers describe details of patient preparation, novel design and execution of the operation as well as unique immunosuppression protocol allowing for lowest long-term maintenance drug regimen. They also share details of the early functional outcomes and demonstrate FFT as a viable option in the treatment of severe facial deformities and injuries. This research is published in the New England Journal of Medicine in the December 27, 2011 issue. http://medicalxpress.com/news/2011-12-transplantation.html Other Wed, 28 Dec 2011 17:00:04 EST news244292445 US health authorities on Thursday urged a 12-week drug regimen for people with latent tuberculosis as an effective alternative to the current nine-month regimen which many people do not finish. http://medicalxpress.com/news/2011-12-urges-shorter-treatment-tb.html Diseases, Conditions, Syndromes Thu, 08 Dec 2011 13:09:46 EST news242572175 President Jacob Zuma on Thursday unveiled a plan to halve the number of HIV infections over the next five years, cementing South Africa's turnaround from years of deadly denialism. http://medicalxpress.com/news/2011-12-south-africa-unveils-halve-hiv.html HIV & AIDS Thu, 01 Dec 2011 13:50:01 EST news241968675 A combination of two drugs may alleviate radiation sickness in people who have been exposed to high levels of radiation, even when the therapy is given a day after the exposure occurred, according to a study led by scientists from Dana-Farber Cancer Institute and Children's Hospital Boston. http://medicalxpress.com/news/2011-11-therapy-sickness.html Cancer Wed, 23 Nov 2011 14:00:01 EST news241275354 (Medical Xpress) -- Northwestern Medicine researchers have launched a clinical trial testing a new combination of treadmill exercise and drug regimen to see if the two together improve the walking ability of people with peripheral arterial disease (PAD) more than either therapy individually. Scientists are studying if a combination of walking and the medication together increase the production of a participant's own stem cells, and, ultimately, the development of greatly needed new blood vessels in the calf muscles. http://medicalxpress.com/news/2011-11-stem-cell-boost-treadmill-artery.html Cardiology Tue, 01 Nov 2011 06:56:20 EST news239349366 Patients being treated for chronic hepatitis C become less likely to take their medications over time, according to a new study from the Perelman School of Medicine at the University of Pennsylvania. Since the study also showed better response to the drugs when they're taken correctly, the researchers say the findings should prompt clinicians to assess patients for barriers to medication adherence throughout their treatment, and develop strategies to help them stay on track. The study is published online this month in Annals of Internal Medicine. http://medicalxpress.com/news/2011-09-hepatitis-patients-falter-adherence-treatment.html Diseases, Conditions, Syndromes Thu, 29 Sep 2011 16:47:54 EST news236533666 Helicobacter pylori, the bacterium known to cause peptic ulcers, is also the primary cause of gastric cancer, which is a leading cancer killer globally. http://medicalxpress.com/news/2011-07-standard-drug-pylori-therapy-regimens.html Medications Wed, 20 Jul 2011 03:57:07 EST news230353013 A study of more than 1,000 patients with colon cancer that had spread to distant sites found that one in eight was treated with at least one drug regimen that was not recommended. Those patients were exposed to significant risk without proven benefits, at an estimated cost—just for the drugs—of more than $2 million. http://medicalxpress.com/news/2011-06-patients-advanced-cancers-treatments-wont.html Cancer Tue, 07 Jun 2011 10:07:23 EST news226660035