http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. An international team, headed by researchers at the University of California, San Diego School of Medicine, has identified a key enzyme in the reprogramming process that promotes malignant stem cell cloning and the growth of chronic myeloid leukemia (CML), a cancer of the blood and marrow that experts say is increasing in prevalence. http://medicalxpress.com/news/2012-12-enzyme-malignant-stem-cell-cloning.html Cancer Mon, 24 Dec 2012 15:00:09 EST news275575816 There are some genes that are only activated in the very first days of an embryo's existence. Once they have accomplished their task, they are shut down forever, unlike most of our genes, which remain active throughout our lives. EPFL scientists have unveiled part of this strange mechanism. The same process, accidentally initiated later in life, could be responsible for many kinds of cancer. The discovery is described in a recent article in the journal Cell Reports. http://medicalxpress.com/news/2012-10-cancer-embryonic-gene-silencing-mechanism-awry.html Genetics Thu, 04 Oct 2012 12:03:56 EST news268571024 Two studies appearing in a recent issue of Cell Transplantation (20:11-12), now freely available online, evaluate stem cells derived from dental tissues for characteristics that may make them therapeutically useful and appropriate for transplantation purposes. http://medicalxpress.com/news/2012-05-cell-transplantation-impact-dental-stem.html Medical research Tue, 08 May 2012 15:24:56 EST news255709488 (Medical Xpress) -- A study published in Genes and Development from scientists at the Friedrich Miescher Institute for Biomedical Research pinpoints the importance of maternal epigenetic influences during early embryogenesis in mammals. A chromatin regulatory complex in the oocyte ensures that the proper luggage of maternal transcripts and chromatin structures control the first steps in the formation of an embryo. In the absence of this epigenetic regulator the embryo fails to develop correctly. http://medicalxpress.com/news/2012-05-mother-maternal-epigenetic-inheritance.html Genetics Mon, 07 May 2012 08:58:44 EST news255599878 Inflammatory breast cancer (IBC) is the most lethal form of breast cancer . It spreads easily through the lymphatic and blood vessels, forming metastasis which can lead to multi-organ failure. New research published in BioMed Central's open access journal Cell Communication and Signaling demonstrates how IBC cells use IL-8, secreted as part of the anti-inflammatory response by a specific set of white blood cells (monocytes), to increase fibronectin expression. http://medicalxpress.com/news/2012-02-metastatic-breast-cancer-hitches-free.html Immunology Fri, 10 Feb 2012 05:30:01 EST news248073643 How is it that a disc-like cluster of cells transforms within the first month of pregnancy into an elongated embryo? This mechanism is a mystery that man has tried to unravel for millennia. http://medicalxpress.com/news/2011-07-scientists-early-human-embryo.html Medical research Tue, 19 Jul 2011 11:40:52 EST news230294438 Scripps Research Institute scientists have discovered a basic mechanism that can enable developing cancer cells to sustain abnormal growth. The finding is expected to lead to the targeting of this mechanism with drugs and diagnostic techniques. http://medicalxpress.com/news/2011-07-scientists-brake-override-proteins-enable-cancers.html Cancer Thu, 07 Jul 2011 11:18:40 EST news229256272