http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. (Medical Xpress)—Researchers at UCLA's Jonsson Comprehensive Cancer Center have discovered the mechanism by which an experimental drug known as GCS-100 removes from lymphoma cells a protein that prevents the cells from responding to chemotherapy. http://medicalxpress.com/news/2012-10-discovery-revives-lymphoma-treatment.html Cancer Mon, 15 Oct 2012 06:04:57 EST news269499850 (Medical Xpress)—An experimental drug can improve sociability in patients with fragile X syndrome and may be helpful as a treatment for autism, according to a study. http://medicalxpress.com/news/2012-09-fragile-drug.html Autism spectrum disorders Mon, 24 Sep 2012 09:46:30 EST news267698775 (Medical Xpress)—A University of Arizona professor is overseeing the manufacture of an experimental drug that could help reduce brain damage after a stroke. http://medicalxpress.com/news/2012-09-experimental-drug-brain-motor-skills.html Medical research Fri, 21 Sep 2012 07:58:08 EST news267433077 (Medical Xpress)—A drug designed for diabetes sufferers could have the potential to treat neurodegenerative diseases like Alzheimer's, a study by scientists at the University of Ulster has revealed. http://medicalxpress.com/news/2012-09-experimental-diabetes-drug-alzheimer-disease.html Alzheimer's disease & dementia Fri, 14 Sep 2012 15:12:20 EST news266854314 (Medical Xpress)—A study by researchers at the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) has discovered how tamoxifen-resistant breast-cancer cells grow and proliferate. It also suggests that an experimental agent might offer a novel targeted therapy for tamoxifen-resistant breast cancer. http://medicalxpress.com/news/2012-08-therapy-tamoxifen-resistant-breast-cancer.html Cancer Thu, 30 Aug 2012 10:24:38 EST news265541068 Lung cancer is one of the most aggressive types of cancer and the most common cause of death from this disease worldwide. Despite the progress in the molecular biology of lung cancer achieved in recent years, the mechanisms used by tumor cells to grow and spread throughout the body are not yet completely understood. This lack of information is responsible for the limited range of available therapeutic possibilities and their undesirable side effects. http://medicalxpress.com/news/2012-08-therapy-lung-cancer-growth-mice.html Cancer Mon, 13 Aug 2012 12:00:04 EST news264065739 Clinical trials start this week for a stroke drug initially created by a team led by scientists at The Scripps Research Institute and the University of Southern California (USC), and further developed by biotech company ZZ Biotech. http://medicalxpress.com/news/2012-08-clinical-trials-drug-scripps-usc.html Medications Wed, 08 Aug 2012 12:48:01 EST news263648874 A team led by a physician-scientist at the University of Southern California (USC) has created an experimental drug that reduces brain damage and improves motor skills among stroke-afflicted rodents when given with federally approved clot-busting therapy. http://medicalxpress.com/news/2012-07-experimental-drug-therapeutic-window.html Cardiology Tue, 17 Jul 2012 16:46:28 EST news261762312 (Medical Xpress) -- A unique multi-target experimental drug could treat a range of cancer types, according to research published in Clinical Cancer Research today. http://medicalxpress.com/news/2012-07-master-experimental-drug-cancers.html Cancer Wed, 11 Jul 2012 09:18:48 EST news261217120 Two new experimental treatments against advanced melanoma have shown promise in keeping the deadly skin cancer at bay, according to research presented in the United States on Monday. http://medicalxpress.com/news/2012-06-treatments-skin-cancer.html Cancer Mon, 04 Jun 2012 04:40:01 EST news258002918 A new cancer treatment that links chemotherapy with an agent that homes in on specific breast cancer cells was significantly better than the current drug regimen at keeping patients' advanced tumors from progressing, according to results from a Phase III clinical trial led by Kimberly Blackwell, M.D., of the Duke Cancer Institute. http://medicalxpress.com/news/2012-06-experimental-drug-aggressive-breast-cancer.html Cancer Sun, 03 Jun 2012 05:58:42 EST news257921911 An experimental drug targeting a common mutation in melanoma successfully shrank tumors that spread to the brain in nine out of 10 patients in part of an international phase I clinical trial report in the May 18 issue of The Lancet. http://medicalxpress.com/news/2012-05-dabrafenib-melanoma-brain-metastases-phase.html Cancer Thu, 17 May 2012 18:30:01 EST news256493208 The experimental drug ibrutinib (PCI-32765) shows great promise for the treatment of elderly patients with chronic lymphocytic leukemia (CLL), according to interim findings from a clinical trial. http://medicalxpress.com/news/2012-05-experimental-agent-older-people-chronic.html Cancer Wed, 16 May 2012 18:00:04 EST news256406942 (HealthDay) -- Researchers are preparing to test an experimental drug in people genetically primed to develop Alzheimer's disease. http://medicalxpress.com/news/2012-05-trial-drug-alzheimer.html Alzheimer's disease & dementia Wed, 16 May 2012 16:10:04 EST news256399609 (AP) -- Look for a fundamental shift in how scientists hunt ways to ward off the devastation of Alzheimer's disease - by testing possible therapies in people who don't yet show many symptoms, before too much of the brain is destroyed. http://medicalxpress.com/news/2012-05-scientists-ways-stall-alzheimer-earlier.html Alzheimer's disease & dementia Wed, 16 May 2012 04:21:28 EST news256360868 Combining the experimental drug Avastin (bevacizumab) with the diabetes drug Metformin almost doubles its ability to reduce skin cancer growth, according to a study in Cancer Discovery. http://medicalxpress.com/news/2012-04-diabetes-treatment-skin-cancer-drug.html Cancer Mon, 02 Apr 2012 07:12:13 EST news252569526 A monthly injection of an experimental drug made by the US biotech firm Amgen reduced patients' cholesterol by up to 66 percent, according to a small study described at a US cardiology conference. http://medicalxpress.com/news/2012-03-monthly-shot-lowers-cholesterol-percent.html Cardiology Mon, 26 Mar 2012 09:46:05 EST news251973958 Italian researchers at the Catholic University of Sacred Heart in Rome found an important molecular mechanism responsible for low back pain and other acute vertebral problems like cervical axial pain, all due to aging and degeneration of the vertebral column. http://medicalxpress.com/news/2012-03-pain-molecular-mechanism-responsible-vertebral.html Medical research Tue, 13 Mar 2012 12:46:50 EST news250861589 The UC Cancer Institute is one of three centers internationally approved to test an experimental drug's safety and pharmacokinetics and also assess the clinical benefit against recurrent malignant glioma, an aggressive form of brain cancer. http://medicalxpress.com/news/2012-02-first-in-human-drug-malignant-glioma-experimental.html Cancer Wed, 15 Feb 2012 11:58:39 EST news248529502 An experimental drug, clazosentan, reduced the risk of blood vessel spasm in patients with a brain aneurysm, according to research presented at the American Stroke Association's International Stroke Conference 2012. http://medicalxpress.com/news/2012-02-experimental-drug-aneurysm-rupture.html Cardiology Wed, 01 Feb 2012 10:26:23 EST news247314374 New research shows that infectious disease-fighting drugs could be designed to block a pathogen's entry into cells rather than to kill the bug itself. http://medicalxpress.com/news/2012-01-strategy-infectious-diseases.html Medical research Mon, 09 Jan 2012 15:00:10 EST news245325555 An experimental drug that works by blocking the export of key control molecules from the nucleus of cancer cells shows promise as a treatment for chronic lymphocytic leukemia (CLL) and other incurable B-cell malignancies, according to a new study by researchers at the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James). http://medicalxpress.com/news/2011-12-export-inhibitor-chronic-lymphocytic-leukemia.html Cancer Mon, 12 Dec 2011 10:29:36 EST news242908166 Just 24 hours after Lisa Rek sang at her niece's wedding, her husband Brad was driving her to a local hospital. http://medicalxpress.com/news/2011-12-university-hospitals-seidman-cancer-center.html Cancer Thu, 01 Dec 2011 12:20:01 EST news241962293 An experimental drug called Ocrelizumab has shown promise in a Phase 2 clinical trial involving 220 people with multiple sclerosis (MS), an often debilitating, chronic autoimmune disease that affects an increasing number of people in North America. It usually strikes young adults and is more common in women than in men. http://medicalxpress.com/news/2011-11-drug-multiple-sclerosis.html Neuroscience Tue, 01 Nov 2011 18:00:01 EST news239388128 An experimental drug designed to fit a DNA patch in a flawed gene has cleared an important hurdle in tests on boys struck by a tragic muscle-wasting disease, a British study on Monday says. http://medicalxpress.com/news/2011-07-drug-muscular-dystrophy.html Medical research Mon, 25 Jul 2011 03:31:33 EST news230783481 A new targeted therapy for prostate cancer halts tumor growth in animals with advanced prostate cancer that is resistant to hormone therapy, a new study finds. The results will be presented Saturday at The Endocrine Society's 93rd Annual Meeting in Boston. http://medicalxpress.com/news/2011-06-cancer-therapy-prostate-tumor-cells.html Cancer Mon, 06 Jun 2011 09:39:51 EST news226571975 A multicenter clinical trial led by a researcher at the University of Maryland Marlene and Stewart Greenebaum Cancer Center will evaluate a new approach to treat triple-negative breast cancer, an often-aggressive type of cancer that is more common among African-Americans and young women. The study will help researchers determine if an experimental drug, entinostat, can reprogram tumor cells to express a protein called an estrogen receptor to make them sensitive to hormone therapy. http://medicalxpress.com/news/2011-06-clinical-trial-approach-triple-negative-breast.html Cancer Thu, 02 Jun 2011 14:24:39 EST news226243467 A new experimental drug selectively kills the cancerous cells that cause chronic lymphocytic leukemia, according to a new study by researchers at the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James). http://medicalxpress.com/news/2011-05-agent-malignant-cells-chronic-leukemia.html Cancer Tue, 03 May 2011 10:34:57 EST news223637678 An experimental drug that blocks two points of a crucial cancer cell signaling pathway inhibits the growth of ovarian cancer cells and significantly increases survival in an ovarian cancer mouse model, a study at UCLA's Jonsson Comprehensive Cancer Center has found. http://medicalxpress.com/news/2011-04-experimental-drug-inhibits-cell-pathway.html Cancer Fri, 15 Apr 2011 10:38:06 EST news222082677 Addicts, even those who have been abstinent for long periods of time, are often still vulnerable to their own memories of prior drug use.  For example, exposure to the same environment in which they commonly used drugs - a contextual memory - can increase their craving for the drug dramatically and can lead to relapse. http://medicalxpress.com/news159687067.html Psychology & Psychiatry Thu, 23 Apr 2009 06:31:35 EST news159687067