http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Predicting outcomes for cancer patients based on tumor-immune system interactions is an emerging clinical approach, and new research from Wake Forest Baptist Medical Center is advancing the field when it comes to the most deadly types of breast cancer. http://medicalxpress.com/news/2013-05-immune-surveillance-war-cancer.html Genetics Thu, 09 May 2013 10:53:22 EST news287315589 A test that measures the expression levels of 58 genes in oestrogen receptor-positive breast cancers can effectively differentiate between patients who are at higher and lower risk for having their cancer recur elsewhere in the body more than five years after diagnosis, researchers report. http://medicalxpress.com/news/2013-05-gene-distinguishes-btw-breast-cancer.html Cancer Thu, 02 May 2013 10:36:11 EST news286709750 Researchers at the Institute for Comprehensive Medical Science, Fujita Health University and the National Institute for Physiological Sciences, Japan, along with colleagues from 9 other institutions, have identified an exceptional mouse model of schizophrenia. After screening over 160 mutant mouse strains with a systematic battery of behavioral tests, they identified a mutant mouse lacking the Schnurri-2 protein (Shn-2 KO) that exhibits behavioral deficits and other brain features consistent with schizophrenia. Shn-2 is an NF-kappaB site-binding protein that binds enhancers of major histocompatibility complex class I genes and inflammatory cytokines, which harbor common variant single nucleotide polymorphisms associated with schizophrenia. The Shn-2 KO mice display behavioral abnormalities that resemble the symptoms of human schizophrenia, including working memory deficits, impaired nest building behavior (a measure of self-neglect), decreased social behaviors, and anhedonia (loss of the ability to experience pleasure). http://medicalxpress.com/news/2013-02-induction-mild-inflammation-cognitive-deficits.html Psychology & Psychiatry Wed, 06 Feb 2013 09:50:11 EST news279366453 Researchers have studied the suitability of Abelmoschus Esculentus (AE) as complementary or as an alternative approach to treat diabetics. http://medicalxpress.com/news/2012-11-okra-natural-alternative-method-diabetes.html Diabetes Fri, 02 Nov 2012 11:26:37 EST news271074372 A research team at Aarhus University reveals a surprising interplay between the ends of human genes: If a protein-coding gene is too short it becomes inactive! The findings also explain how some short genes have adapted to circumvent this handicap. http://medicalxpress.com/news/2012-10-length-gene.html Genetics Tue, 02 Oct 2012 11:03:42 EST news268394615 Thyroid nodules are thought to be present in about half of all people, but very few of these are cancerous. New research published in BioMed Central's open access journal BMC Cancer presents a set of diagnostic biomarkers which are able to distinguish between malignant and benign thyroid nodules. http://medicalxpress.com/news/2012-09-diagnosis-thyroid-nodules.html Cancer Thu, 06 Sep 2012 20:00:02 EST news266166442 The more that we understand the brain, the more complex it becomes. The same can be said about the genetics and neurobiology of psychiatric disorders. For "Mendelian" disorders, like Huntington disease, mutation of a single gene predictably produces a single clinical disorder, following relatively simple genetic principals. Compared to Mendelian disorders, understanding bipolar disorder has been extremely challenging. Its biology is not well understood and its genetics are complex. http://medicalxpress.com/news/2012-08-biological-matrix-bipolar-disorder.html Psychology & Psychiatry Mon, 20 Aug 2012 10:24:23 EST news264677053 (Medical Xpress) -- Expression levels of a DNA repair gene called MGMT have been widely studied across many cancers as a biomarker of response to temozolomide, a chemotherapeutic agent. Now Australian scientists have published findings suggesting MGMT may also play a significant role in tumour progression. http://medicalxpress.com/news/2012-07-pituitary-tumours-biology-cancers.html Cancer Mon, 30 Jul 2012 08:15:26 EST news262854791 Severe pain is a major symptom of pancreatic cancer. The results of a new study show that four different factors involved in the growth and maintenance of nerves are elevated in a mouse model of pancreatic cancer. This is a step forward in understanding the relationship between the development of pain and the progression of pancreatic cancer. http://medicalxpress.com/news/2012-06-nerve-growth-factors-elevated-pancreatic.html Cancer Tue, 19 Jun 2012 11:06:03 EST news259322748 Using a new and powerful approach to understand the origins of neurodegenerative disorders such as Alzheimer's disease, researchers at Mayo Clinic in Florida are building the case that these diseases are primarily caused by genes that are too active or not active enough, rather than by harmful gene mutations. http://medicalxpress.com/news/2012-06-genes-factors-neurodegenerative-diseases.html Genetics Thu, 07 Jun 2012 17:00:30 EST news258305913 Recent work in mice suggested that the immune system is involved in removing beta-amyloid, the main Alzheimer's-causing substance in the brain. Researchers have now shown for the first time that this may apply in humans. http://medicalxpress.com/news/2012-05-immune-alzheimer-humans.html Alzheimer's disease & dementia Fri, 25 May 2012 10:12:30 EST news257159529 A research team this week will present findings that they say may finally explain the link between alcohol consumption and breast cancer. http://medicalxpress.com/news/2012-04-potential-link-alcohol-breast-cancer.html Cancer Mon, 23 Apr 2012 15:30:05 EST news254397394 A team of Japanese researchers will reveal study results Monday at the Experimental Biology 2012 meeting that show how acupuncture therapy mitigates skeletal muscle loss and holds promise for those seeking improved mobility through muscle rejuvenation. http://medicalxpress.com/news/2012-04-japanese-acupuncture-skeletal-muscle-atrophy.html Medical research Mon, 23 Apr 2012 15:30:01 EST news254397275 A new study lead by the Neuroscience Institute of Alicante reveals how manipulating the endocannabinoid system can modulate high levels of impulsivity. This is the main problem in psychiatric illnesses such a schizophrenia, bipolar disorder and substance abuse. http://medicalxpress.com/news/2012-03-cannabinoid-receptors-impulsive-behavior.html Psychology & Psychiatry Thu, 08 Mar 2012 10:23:50 EST news250424624 Age-related macular degeneration (AMD) is one of the leading causes of blindness worldwide, especially in developed countries, and there is currently no known treatment or cure or for the vast majority of AMD patients. New research published in BioMed Central's open access journal Genome Medicine has identified genes whose expression levels can identify people with AMD, as well as tell apart AMD subtypes. http://medicalxpress.com/news/2012-02-genetic-basis-age-related-macular-degeneration.html Genetics Thu, 23 Feb 2012 19:00:02 EST news249241684 Most research on glioblastoma development, a complicated tumor of the brain with a poor prognosis, has focused on the gene transcription level, but scientists suggest that post-transcriptional regulation could be equally or even more important. http://medicalxpress.com/news/2012-01-scientists-uncover-mechanism-glioblastoma.html Cancer Wed, 18 Jan 2012 03:46:26 EST news246080765 A team of researchers, led by King's College London and the University of Oxford, have found that a gene linked to type 2 diabetes and cholesterol levels is in fact a 'master regulator' gene, which controls the behaviour of other genes found within fat in the body. http://medicalxpress.com/news/2011-05-master-gene-obesity-diabetes.html Genetics Sun, 15 May 2011 13:00:01 EST news224506528