http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Predicting outcomes for cancer patients based on tumor-immune system interactions is an emerging clinical approach, and new research from Wake Forest Baptist Medical Center is advancing the field when it comes to the most deadly types of breast cancer. http://medicalxpress.com/news/2013-05-immune-surveillance-war-cancer.html Genetics Thu, 09 May 2013 10:53:22 EST news287315589 Breast cancers contain many different cell types with different patterns of gene expression, but a new study provides reassurance that this variability should not be a barrier to using gene expression tests to help tailor cancer treatments to individual patients. http://medicalxpress.com/news/2013-05-breast-cancer-heterogeneity-barrier.html Cancer Thu, 02 May 2013 09:21:30 EST news286705284 Using advanced genetic sequencing technology and analysis, Mayo Clinic vaccine researchers have identified 27 genes that respond in very different ways to the standard rubella vaccine, making the vaccine less effective for a portion of the population. The findings appear today in the online journal PLOS ONE. http://medicalxpress.com/news/2013-05-dont-rubella-vaccine.html Immunology Wed, 01 May 2013 17:00:11 EST news286628460 In recent years, it has been thought that select sets of genes might reveal cancer patients' prognoses. However, a study published last year examining breast cancer cases found that most of these "prognostic signatures" were no more accurate than random gene sets in determining cancer prognoses. While many saw this as a disappointment, investigators at Beth Israel Deaconess Medical Center (BIDMC), the Dana-Farber Cancer Institute, and the Institut de Recherches Cliniques de Montréal (IRCM) saw this as an opportunity to design a new method to identify gene sets that could yield more significant prognostic value. http://medicalxpress.com/news/2013-01-method-genes-prognoses-cancer-patients.html Genetics Fri, 25 Jan 2013 09:06:26 EST news278327168 (Medical Xpress)—A new Australian study led by Professor Susan Clark from Sydney's Garvan Institute of Medical Research shows that large regions of the genome – amounting to roughly 2% – are epigenetically activated in prostate cancer. http://medicalxpress.com/news/2012-12-cancer-overturns-current-gene.html Cancer Tue, 18 Dec 2012 16:06:03 EST news275069088 Scientists in Australia and Austria have described a "network map" of genes involved in pain perception. The work, published in the journal PLOS Genetics should help identify new analgesic drugs. http://medicalxpress.com/news/2012-12-valuable-tool-pain-genes-people.html Genetics Thu, 06 Dec 2012 17:30:02 EST news274031875 (Medical Xpress)—An interdisciplinary team of researchers has dissected a case of synergy in drug-resistant chronic myeloid leukemia to understand the mechanism by which two drugs, danusertib and bosutinib, work together to overcome resistance in the BCR-ABL gatekeeper mutation-specific disease. The team includes a researcher at Moffitt Cancer Center and colleagues at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences in Austria and the Massachusetts Institute of Technology. The goal is to address an unmet medical need because this BCR-ABL mutation confers resistance to all currently approved kinase inhibitors for chronic myeloid leukemia. http://medicalxpress.com/news/2012-10-moffitt-drug-synergy-drug-resistant-chronic.html Cancer Wed, 24 Oct 2012 12:40:04 EST news270300608 Researchers at Wake Forest Baptist Medical Center have demonstrated that cancer of the appendix is different than colon cancer, a distinction that could lead to more effective treatments for both diseases. http://medicalxpress.com/news/2012-03-cancer-appendix.html Cancer Wed, 07 Mar 2012 15:37:23 EST news250357037