http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Novel abnormalities in the FGFR gene, called FGFR fusions, were identified in a spectrum of cancers, and preliminary results with cancer cells harboring FGFR fusions suggested that some patients with these cancers may benefit from treatment with FGFR inhibitor drugs, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research. http://medicalxpress.com/news/2013-06-clinical-sequencing-technology-diverse-cancers.html Cancer Fri, 07 Jun 2013 15:28:55 EST news289837728 By looking at the entire DNA from this one patient's tumor, researchers have found a genetic anomaly that provides an important clue to improving how this cancer is diagnosed and treated. http://medicalxpress.com/news/2013-01-genetic-mutation-rare-cancer.html Genetics Tue, 15 Jan 2013 10:27:41 EST news277468033 Prostate cancer is generally treated as if it's a single disease. But researchers have discovered a new type of the cancer that appears to affect 15 percent of patients, a finding that paves the way for better diagnosis and more targeted therapies down the road. http://medicalxpress.com/news/2012-09-gene-mutation-proteins-tumor-growth.html Cancer Fri, 07 Sep 2012 13:47:08 EST news266244418 Researchers at Columbia University Medical Center (CUMC) have discovered that some cases of glioblastoma, the most common and aggressive form of primary brain cancer, are caused by the fusion of two adjacent genes. The study also found that drugs that target the protein produced by this genetic aberration can dramatically slow the growth of glioblastomas in mice. The findings were published today in the online edition of the journal Science. http://medicalxpress.com/news/2012-07-genetic-lethal-brain-tumor-treatment.html Cancer Thu, 26 Jul 2012 14:00:01 EST news262521194 Researchers have identified a potential new pathway in prostate cancer cells by which cancer-driving gene products can be generated, according to a study published in Cancer Discovery, a journal of the American Association for Cancer Research. http://medicalxpress.com/news/2012-06-abnormal-gene-product-prostate-cancer.html Cancer Tue, 19 Jun 2012 10:51:59 EST news259321786 Smoking is a well-known risk factor for lung cancer, but nearly 25% of all lung cancer patients have never smoked. In a study published online today in Genome Research, researchers have identified a previously unknown gene fusion event that could explain a significant proportion of lung cancer cases in never-smokers, and might serve as a target for new therapies. http://medicalxpress.com/news/2011-12-gene-fusion-lung-cancer-afflicting.html Genetics Thu, 22 Dec 2011 13:00:01 EST news243777177 About 15 percent of cases of an aggressive, difficult-to-detect form of ovarian cancer contain a unique fusion between two neighboring, normally separate genes, say researchers at the Stanford University School of Medicine. Although gene fusions are known to occur in prostate and some blood cancers, they have been notoriously difficult to identify in solid tumors. This is the first recurrent gene fusion found for ovarian cancer. http://medicalxpress.com/news/2011-09-discovery-gene-fusion-ovarian-cancer.html Genetics Tue, 20 Sep 2011 17:41:57 EST news235759274 About half of prostate cancers have a genetic anomaly that appears to make tumor cells responsive to a new class of cancer-fighting drugs, a new study from the University of Michigan Comprehensive Cancer Center finds. http://medicalxpress.com/news/2011-05-prostate-cancers-potentially-benefit-cancer.html Cancer Wed, 18 May 2011 10:13:15 EST news224932386