http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. (Medical Xpress) -- An international team of scientists, including researchers from Karolinska Institutet, have identified several rare gene variants that predispose to IBD (Inflammatory Bowel Disease). The study provides new insights into disease pathogenesis, and suggests next-generation sequencing may speed hoped-for personalized treatment of common complex disorders. http://medicalxpress.com/news/2011-10-rare-gene-variants-linked-inflammatory.html Inflammatory disorders Mon, 10 Oct 2011 10:26:51 EST news237461097 (Medical Xpress) -- Virginia Commonwealth University School of Medicine researchers, working with an international team of colleagues, have identified a gene that may play a role in causing a neurodevelopmental disorder that includes intellectual disability, seizures and autism spectrum disorder. http://medicalxpress.com/news/2011-10-gene-intellectual-disability-epilepsy-autistic.html Genetics Fri, 07 Oct 2011 09:21:30 EST news237198081 (Medical Xpress) -- Awareness of male breast cancer is low and most men do not even know they are at risk despite an increase in cases, reveals new research from the University of Leeds. http://medicalxpress.com/news/2011-10-awareness-male-breast-cancer-cases.html Cancer Mon, 03 Oct 2011 10:27:13 EST news236856408 Queensland Brain Institute (QBI) researchers have discovered a genetic mechanism that may explain why the children of older fathers are more likely to develop schizophrenia or autism. http://medicalxpress.com/news/2011-09-mutation-clue-disorders-older-dads.html Psychology & Psychiatry Thu, 01 Sep 2011 09:08:21 EST news234086882 Scientists have discovered a genetic cause of extreme thinness for the first time, in a study published today in the journal Nature. http://medicalxpress.com/news/2011-08-gene-overdose-extreme-thinness.html Genetics Wed, 31 Aug 2011 13:18:28 EST news234015497 Hospitals struggle to prevent the infections that complicate treatment for cancer, joint replacement, heart surgery and other conditions. Hospital-acquired infections are often resistant to multiple antibiotics, leading to approximately 100,000 deaths and more than $30 billion in additional health care costs yearly. New drugs are being developed to combat these infections, but resistance invariably emerges to these last-line drugs. http://medicalxpress.com/news/2011-07-insight-drug-resistance-hospital-microbes.html Medical research Wed, 13 Jul 2011 15:29:37 EST news229789767 Until a decade, it was believed that differences between people were due solely to the existence of genetic changes, which are alterations in the sequence of our genes. The discoveries made during these last ten years show that beings with the same genetics like the twins and cloned animals may have different characteristics and disease due to epigenetic changes. http://medicalxpress.com/news/2011-06-characterize-epigenetic-fingerprint-people.html Genetics Thu, 02 Jun 2011 06:45:38 EST news226215920 Genetic analysis of the tumors from patients with advanced melanoma can clue researchers in to how well patients will respond to a therapy that targets the growth-promoting protein called BRAF, a researcher from the Perelman School of Medicine at the University of Pennsylvania will report on Monday, June 6 at the annual meeting of the American Society of Clinical Oncology. Looking outside of the BRAF gene, the researchers found loss of the tumor suppressor gene PTEN also appears to be associated with patient response to GSK436, which could help guide researchers to even more personalized approaches to melanoma therapy. http://medicalxpress.com/news/2011-06-genes-response-braf-inhibitors-advanced.html Cancer Wed, 01 Jun 2011 15:07:15 EST news226159402 Years ago, identical twin baby boys received a blood transfusion tainted with HIV. Today, one twin is relatively healthy with a near-normal immune system, but his brother is five years behind on the growth chart and has developed many complications. http://medicalxpress.com/news/2011-04-hiv.html HIV & AIDS Fri, 29 Apr 2011 12:10:01 EST news223295547 A team led by researchers at the National Institutes of Health is the first to systematically survey the landscape of the melanoma genome, the DNA code of the deadliest form of skin cancer. The researchers have made surprising new discoveries using whole-exome sequencing, an approach that decodes the 1-2 percent of the genome that contains protein-coding genes. The study appears in the April 15, 2011, early online issue of Nature Genetics. http://medicalxpress.com/news/2011-04-whole-exome-sequencing-skin-cancer.html Genetics Fri, 15 Apr 2011 10:47:35 EST news222083240