http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive breast cancer cells that are resistant to hormone therapies such as tamoxifen, aromatase inhibitors or fulvestrant. http://medicalxpress.com/news/2013-04-breast-cancer-drug-companion-prognostic.html Cancer Mon, 01 Apr 2013 15:00:01 EST news284032748 In 2010, 35 people in Greece died from a West Nile virus (WNV) outbreak, with a further 262 laboratory-confirmed human cases. A new article published in BioMedCentral's open access journal Virology Journal examines whether wild or migratory birds could have been responsible for importing and amplifying the deadly virus. http://medicalxpress.com/news/2012-11-wild-birds-deadly-west-nile.html Diseases, Conditions, Syndromes Sun, 11 Nov 2012 20:00:01 EST news271871413 African Americans have higher blood levels of a protein associated with increased heart-disease risk than European Americans, despite higher "good" HDL cholesterol and lower "bad" triglyceride levels. This contradictory observation now may be explained, in part, by a genetic variant identified in the first large-scale, genome-wide association study of this protein involving 12,000 African American and Hispanic American women. http://medicalxpress.com/news/2012-08-genetic-factor-inflammation-african-american.html Genetics Thu, 30 Aug 2012 12:00:01 EST news265546405 Scientific understanding and medical treatments for dyslexia have advanced over the past 5 years, but much work remains to be done to fully understand the causes of dyslexia and to improve the lives of children who struggle to learn to read, according to a Seminar published Online First in The Lancet. Indeed, most children are only diagnosed with dyslexia after they have experienced serious difficulties in school, at a time when it is much harder for them to master new skills, and this could be preventing children with dyslexia from achieving the best outcomes. http://medicalxpress.com/news/2012-04-children-dyslexia.html Diseases, Conditions, Syndromes Mon, 16 Apr 2012 18:30:01 EST news253814296 The University of Michigan Health and Retirement Study, a 20-year nationwide survey of the health, economic and social status of older Americans conducted by the U-M Institute for Social Research, has added genetic information from 12,500 consenting participants to the online genetics database of the National Institutes of Health. http://medicalxpress.com/news/2012-03-u-m-health-genetic-nih-database.html Genetics Wed, 28 Mar 2012 11:51:55 EST news252154307 A line of laboratory mice developed by a researcher from the School of Science at Indiana University-Purdue University Indianapolis drinks more alcohol than other animal models and consumes it in a fashion similar to humans: choosing alcohol over other options and binge drinking. http://medicalxpress.com/news/2011-12-strain-lab-mice-mimics-human.html Medical research Mon, 12 Dec 2011 11:12:38 EST news242910752 Researchers know that gender differences exist in the prevalence, characteristics, and course of alcohol dependence (AD). Polymorphisms of alcohol dehydrogenase-1B (ADH1B) and aldehyde dehydrogenase-2 (ALDH2) are strong genetic determinants of AD. A new study of gender differences in the effects of these polymorphisms on the development of AD has found that inactive ALDH2 can accelerate the development of AD in women. http://medicalxpress.com/news/2011-08-aldehyde-dehydrogenase-polymorphism-affects-alcohol.html Other Mon, 15 Aug 2011 16:00:06 EST news232642090