http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Results of two studies suggest that a new, investigational colorectal cancer screening test developed in a collaboration between Mayo Clinic and Exact Sciences Inc. of Madison, Wis., is highly accurate and significantly more sensitive than other noninvasive tests at detecting precancerous tumors (adenomas) and early-stage cancer. These findings have important implications for clinicians and tens of thousands of Americans. Early detection is a key driver of better outcomes for colorectal cancer -- a disease that affects 1 in every 17 persons and is the second-leading cause of U.S. cancer deaths. http://medicalxpress.com/news/2012-01-greater-accuracy-early-colorectal-cancer.html Cancer Thu, 19 Jan 2012 10:14:01 EST news246190417 The Lawson Translational Cancer Research Team (LTCRT) of the Lawson Health Research Institute is one of five groups participating in a new study that seeks to personalize cancer drug treatment. http://medicalxpress.com/news/2011-12-lawson-team-personalize-cancer.html Cancer Mon, 12 Dec 2011 13:00:03 EST news242916553 Scientists at Mount Sinai Hospital, in collaboration with researchers at the University of Toronto, University Health Network and McGill University have obtained significant new insights into the causes of rheumatoid arthritis (RA) and other autoimmune disorders including type 1 diabetes, lupus and Graves disease. http://medicalxpress.com/news/2011-08-genetic-clue-rheumatoid-arthritis.html Genetics Sun, 14 Aug 2011 13:00:08 EST news232545414 Mutations in three genes have been identified that are more prevalent in patients with esophageal cancer and Barrett esophagus, a premalignant metaplasia (change in cells or tissue) caused by chronic gastroesophageal reflux disease (GERD), according to preliminary research reported in the July 27 issue of JAMA. http://medicalxpress.com/news/2011-07-genetic-link-barrett-esophagus-esophageal.html Genetics Tue, 26 Jul 2011 16:00:07 EST news230885852 The authors of a widely reported study that offered an early glimpse into factors leading to long life are withdrawing the paper because of problems with some of the data they used. http://medicalxpress.com/news/2011-07-living-long-paper-withdrawn.html Genetics Thu, 21 Jul 2011 16:16:33 EST news230483768 A genome-wide study by researchers at the RIKEN Center for Genomic Medicine, Hiroshima University Hospital and Sapporo-Kosei General Hospital has identified a genetic variant associated with the development of liver cancer in chronic hepatitis C virus carriers. The findings are based on a study of 3,312 Japanese individuals and appear in the journal Nature Genetics. http://medicalxpress.com/news/2011-07-genetic-variant-linked-liver-cancer.html Genetics Sun, 03 Jul 2011 13:00:01 EST news228916647 Researchers have developed a new strategy to improve the outcome of genome-wide association (GWA) studies. http://medicalxpress.com/news/2011-06-approach-link-genome-wide-association-biological.html Genetics Thu, 30 Jun 2011 17:40:36 EST news228674413 A recently released paper in the Proceedings of the National Academy of Sciences (PNAS), "The Role of Mother's Genes and Environment in Postpartum Depression," explores the interplay between genes and environment when determining whether a mother is at high or low risk for post-partum depression. Daniel Notterman, vice dean for research at Penn State College of Medicine, was part of a multi-university team including Princeton, Columbia and University of York (UK) that conducted the study. http://medicalxpress.com/news/2011-06-postpartum-depression-gene-behavior-differs.html Psychology & Psychiatry Thu, 09 Jun 2011 07:07:30 EST news226821979 Prostate cancer is the most commonly diagnosed cancer in men. But it can be difficult to diagnose, and it’s hard to know which cancers will become dangerous and which need less-aggressive treatment. Researchers and clinicians alike are eager to identify molecular markers or other characteristics that will enable them to accurately diagnose the disease, and then parse the deadly from the dormant and target treatment accordingly. http://medicalxpress.com/news/2011-05-genetic-markers-treatment-prostate-cancer.html Genetics Mon, 23 May 2011 10:32:22 EST news225365529 (Medical Xpress) -- As part of the continuing Fragile Families and Child Wellbeing Study, launched in 1997, researchers, including Professor John Hobcraft, of York’s Department of Social Policy and Social Work and academics from Princeton, Penn State and Columbia Universities in the USA, examined the DNA of more than 1,200 mothers. http://medicalxpress.com/news/2011-05-reveals-environment-role-post-natal-depression.html Psychology & Psychiatry Fri, 20 May 2011 12:42:03 EST news225114111 Measuring the transfer of tiny amounts of energy from one protein to another on breast cancer cells has given scientists a detailed view of molecular interactions that could help predict how breast cancer patients will respond to particular therapies. http://medicalxpress.com/news/2011-05-protein-snapshots-reveal-clues-breast.html Cancer Thu, 05 May 2011 09:54:12 EST news223807994 Researchers at Mount Sinai School of Medicine, in collaboration with researchers at Loyola University Chicago Stritch School of Medicine, have made a critical discovery that may lead scientists to abandon the use of broad conventional ethnic labels—African-American, Hispanic, and Caucasian—to estimate a patient's genetic risk for disease. This first-of-its kind study conducted with diverse patients receiving care at a single urban academic medical center, marks an important step in the clinical application of personalized medicine. The data are published online in the peer-reviewed journal PLoS ONE. http://medicalxpress.com/news/2011-05-shift-personalized-medicine.html Genetics Wed, 04 May 2011 17:29:15 EST news223748938 By dividing individuals with autism spectrum disorders (ASD) into four subtypes according to similarity of symptoms and reanalyzing existing genome-wide genetic data on these individuals vs. controls, researchers at the George Washington University School of Medicine and Health Sciences have identified 18 novel and highly significant genetic markers for ASD. http://medicalxpress.com/news/2011-04-subtype-dependent-genetic-variants-autism-spectrum.html Genetics Wed, 27 Apr 2011 17:16:38 EST news223143369 Daniel Klein '11 always considered himself a European with an Ashkenazi Jewish heritage. But after receiving DNA results from the Cornell Genetic Ancestry Project, Klein got a big surprise. http://medicalxpress.com/news/2011-04-ancestry-reveals-students-genetic-histories.html Genetics Wed, 20 Apr 2011 08:34:04 EST news222507225