http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. A team of researchers led by Washington University School of Medicine in St. Louis has identified virtually all of the major mutations that drive acute myeloid leukemia (AML), a fast-growing blood cancer in adults that often is difficult to treat. http://medicalxpress.com/news/2013-05-scientists-genetic-playbook-acute-leukemia.html Cancer Wed, 01 May 2013 13:00:34 EST news286625897 Powerful data-sifting algorithms developed by computer scientists at Brown University are helping to untangle the profoundly complex genetics of cancer. In a study reported today in the New England Journal of Medicine, researchers from Washington University in St. Louis used two algorithms developed at Brown to assemble the most complete genetic profile yet of acute myeloid leukemia (AML), an aggressive form of blood cancer. The researchers hope the work will lead to new AML treatments based on the genetics of each patient's disease. http://medicalxpress.com/news/2013-05-algorithms-cancer.html Cancer Wed, 01 May 2013 13:00:02 EST news286625709 (Medical Xpress)—A Purdue University study found an agricultural herbicide alters reproductive and neuroendocrine genes during embryonic development in fish, a finding that will help establish a genetic profile to determine atrazine's specific effects. http://medicalxpress.com/news/2013-04-legal-atrazine-neuroendocrine-reproductive-genes.html Medical research Wed, 03 Apr 2013 08:50:47 EST news284197783 Researchers have identified genetic risk factors that may accelerate a teen's progression to becoming a lifelong heavy smoker. http://medicalxpress.com/news/2013-03-genetics-smokers.html Psychology & Psychiatry Wed, 27 Mar 2013 16:00:01 EST news283614819 A drug that indirectly impairs the function of several cancer-driving proteins, including anaplastic lymphoma kinase (ALK), may be an effective new treatment for patients with ALK—positive non-small cell lung cancer. http://medicalxpress.com/news/2013-03-ganetespib-potency-alk-positive-lung-cancer.html Cancer Tue, 26 Mar 2013 13:30:17 EST news283523409 An extensive genomic study of the childhood cancer neuroblastoma reinforces the challenges in treating the most aggressive forms of this disease. Contrary to expectations, the scientists found relatively few recurrent gene mutations—mutations that would suggest new targets for neuroblastoma treatment. Instead, say the researchers, they have now refocused on how neuroblastoma tumors evolve in response to medicine and other factors. http://medicalxpress.com/news/2013-01-tumors-evolve-rapidly-childhood-cancer.html Genetics Sun, 20 Jan 2013 13:00:27 EST news277901484 Genomic sequencing has revealed therapeutic drug targets for difficult-to-treat, metastatic triple-negative breast cancer (TNBC), according to an unprecedented study by the Translational Genomic Research Institute (TGen) and US Oncology Research. http://medicalxpress.com/news/2012-12-tgen-us-oncology-treatment-metastatic-triple-negative.html Cancer Thu, 06 Dec 2012 15:19:37 EST news274029561 In a new theoretical study, 23andMe, the personal genetics company, developed a mathematical model which shows that family history and genetic tests offer different strengths. The study results suggest that both family history and genetics are best used in combination to improve disease risk prediction. The full results of the study have now been published online in the journal PLOS Genetics. http://medicalxpress.com/news/2012-10-family-history-genetic-complex-disease.html Genetics Mon, 15 Oct 2012 16:39:42 EST news269537963 Cardiomyocytes, the workhorse cells that make up the beating heart, can now be made cheaply and abundantly in the laboratory. http://medicalxpress.com/news/2012-05-stem-cell-technique-abundance-key.html Medical research Mon, 28 May 2012 15:00:11 EST news257415820 Tuberculosis patients may receive treatments in the future according to what version they have of a single 'Goldilocks' gene, says an international research team from Oxford University, King's College London, Vietnam and the USA. http://medicalxpress.com/news/2012-02-goldilocks-gene-treatment-tuberculosis-patients.html Genetics Thu, 02 Feb 2012 12:00:05 EST news247402781 The Lawson Translational Cancer Research Team (LTCRT) of the Lawson Health Research Institute is one of five groups participating in a new study that seeks to personalize cancer drug treatment. http://medicalxpress.com/news/2011-12-lawson-team-personalize-cancer.html Cancer Mon, 12 Dec 2011 13:00:03 EST news242916553 One of the causes of resistance to cancer treatment in children is now beginning to be elucidated. Acute lymphoblastic leukemia patients with a particular form of the ATF5 gene are at higher risk of having a relapse when treated with E. coli asparaginase, a key chemotherapy drug for this type of leukemia. This is what a study by Dr. Maja Krajinovic published in the Blood, the journal of the American Society of Hematology, reveals Dr. Krajinovic is an investigator at the Sainte-Justine University Hospital Research Center, which is affiliated with the University of Montreal. http://medicalxpress.com/news/2011-10-gene-responsible-relapses-young-leukemia.html Cancer Wed, 26 Oct 2011 13:33:50 EST news238854821 According to a group of geneticists in Switzerland from iGENEA, the DNA genealogy center, as many as half of all European men and 70 percent of British men share the same DNA as the Egyptian Pharaoh Tutankhamun, or King Tut. http://medicalxpress.com/news/2011-08-king-tut-european-men-dna.html Genetics Wed, 03 Aug 2011 10:30:07 EST news231584002 A new study by researchers at Wake Forest Baptist Medical Center sheds light on what causes certain kidneys to do better than others after being transplanted, providing doctors with an easy way to screen for donor kidneys that have the best chance of survival. http://medicalxpress.com/news/2011-05-genes-donor-kidney-survival.html Other Tue, 10 May 2011 03:59:47 EST news224218748 Smoke from cigarettes can affect nearly every organ in the body by promoting cell damage and causing inflammation, but no one has understood which smoker is or is not susceptible to disease development. http://medicalxpress.com/news/2011-04-methods-cigarette-affects-smokers.html Cancer Wed, 06 Apr 2011 09:24:58 EST news221300687