http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. More than 100 doctors from around the world have signed a letter decrying the high cost of cancer drugs which reach $100,000 per year or more, and calling for pharmaceutical companies to ease prices. http://medicalxpress.com/news/2013-04-doctors-cancer-drug-high.html Medications Fri, 26 Apr 2013 13:35:55 EST news286202148 A new preclinical technology enables researchers to quickly determine if a particular treatment is effective against gastrointestinal stromal tumors (GISTs), providing a boost to animal research and possibly patient care, according to new findings presented by Fox Chase Cancer Center at the AACR Annual Meeting 2013 on Tuesday, April 9. http://medicalxpress.com/news/2013-04-technology-drugs-early-impact-cancer.html Cancer Tue, 09 Apr 2013 13:00:03 EST news284730684 India's Supreme Court on Monday rejected drug maker Novartis AG's attempt to patent an updated version of a cancer drug in a landmark decision that health activists say ensures poor patients around the world will get continued access to cheap versions of lifesaving medicines. http://medicalxpress.com/news/2013-04-drug-maker-india-patent.html Medications Mon, 01 Apr 2013 04:28:55 EST news284009309 India's Supreme Court is to rule Monday on a landmark patent case involving Swiss drugmaker Novartis AG that focuses on demands by major companies that their investments be protected, against Indian companies that say they should be allowed to continue producing cheaper generic versions of many lifesaving medicines. http://medicalxpress.com/news/2013-03-india-court-novartis-judgment.html Medications Sun, 31 Mar 2013 09:20:01 EST news283939647 The U.S. Food and Drug Administration on Monday expanded approval of a Bayer cancer pill to treat tumors of the intestinal tract that do not respond to other treatments. http://medicalxpress.com/news/2013-02-fda-bayer-cancer-drug.html Medications Mon, 25 Feb 2013 16:30:01 EST news281031295 (Medical Xpress)—A drug that is currently used for cancer can relieve and slow down the progression of the autoimmune disease multiple sclerosis (MS) in rats, according to a new study published in PLOS ONE. The discovery, which was made by researchers at Karolinska Institutet, might one day lead to better forms of treatment for patients with MS. http://medicalxpress.com/news/2013-02-cancer-drug-treatment-multiple-sclerosis.html Medical research Thu, 21 Feb 2013 10:02:01 EST news280663311 An antibody that binds to a molecule on the surface of a rare but deadly tumor of the gastrointestinal tract inhibits the growth of the cancer cells in mice, according to researchers at the Stanford University School of Medicine. http://medicalxpress.com/news/2013-02-antibody-hinders-growth-gleevec-resistant-gastrointestinal.html Cancer Mon, 04 Feb 2013 15:00:08 EST news279195778 (HealthDay)—The anti-cancer drug Gleevec (imatinib) has received new U.S. Food and Drug Administration approval to treat the most common type of pediatric cancer, affecting some 2,900 children each year, the agency said Friday. http://medicalxpress.com/news/2013-01-gleevec-latest-pediatric-cancer.html Cancer Fri, 25 Jan 2013 16:55:35 EST news278355318 Researchers at the University of California, San Diego School of Medicine have discovered that hard-to-reach, drug-resistant leukemia stem cells (LSCs) that overexpress multiple pro-survival protein forms are sensitive – and thus vulnerable – to a novel cancer stem cell-targeting drug currently under development. http://medicalxpress.com/news/2013-01-drug-hard-to-reach-leukemia-stem-cells.html Cancer Thu, 17 Jan 2013 12:00:18 EST news277642727 (AP)—From Africa's crowded AIDS clinics to the malarial jungles of Southeast Asia, the lives of millions of ill people in the developing world are hanging in the balance ahead of a legal ruling that will determine whether India's drug companies can continue to provide cheap versions of many life-saving medicines. http://medicalxpress.com/news/2013-01-indian-court-drug-industry.html Medications Fri, 04 Jan 2013 04:57:22 EST news276497833 A new targeted drug demonstrated its ability to control metastatic gastrointestinal stromal tumor, an uncommon and life-threatening form of sarcoma, after the disease had become resistant to all existing therapies, report investigators at Dana-Farber Cancer Institute who led the worldwide clinical trial. http://medicalxpress.com/news/2012-11-drug-resistance-patients-rare-sarcoma.html Cancer Wed, 21 Nov 2012 18:30:09 EST news272740107 Physician-researchers at Indiana University School of Medicine have reported the first effective therapy for a class of previously untreatable and potentially life-threatening tumors often found in children. http://medicalxpress.com/news/2012-11-effective-treatment-tumors-common-genetic.html Cancer Thu, 01 Nov 2012 13:45:34 EST news270996324 (Medical Xpress)—An interdisciplinary team of researchers has dissected a case of synergy in drug-resistant chronic myeloid leukemia to understand the mechanism by which two drugs, danusertib and bosutinib, work together to overcome resistance in the BCR-ABL gatekeeper mutation-specific disease. The team includes a researcher at Moffitt Cancer Center and colleagues at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences in Austria and the Massachusetts Institute of Technology. The goal is to address an unmet medical need because this BCR-ABL mutation confers resistance to all currently approved kinase inhibitors for chronic myeloid leukemia. http://medicalxpress.com/news/2012-10-moffitt-drug-synergy-drug-resistant-chronic.html Cancer Wed, 24 Oct 2012 12:40:04 EST news270300608 In a paper published today in the journal Cell, a team from the University of North Carolina at Chapel Hill unveils the first broad-based test for activation of protein kinases "en masse", enabling measurement of the mechanism behind drug-resistant cancer and rational prediction of successful combination therapies. http://medicalxpress.com/news/2012-04-kinase-yield-big-gains-drug-resistant.html Cancer Thu, 12 Apr 2012 12:00:04 EST news253441476 Researchers reporting in the April Cell Stem Cell, a Cell Press publication, have found a way to stop leukemia stem cells in their tracks. The advance in mice suggests that a combination approach to therapy might stamp out chronic myeloid leukemia (CML) for good. http://medicalxpress.com/news/2012-04-leukemia-dreaded-stem-cells.html Cancer Thu, 05 Apr 2012 12:00:10 EST news252844867 By reformulating the common cancer drug imatinib (Gleevec), researchers have eliminated morphine tolerance in rats – an important step toward improving the effectiveness of chronic pain management in patients, according to researchers at The University of Texas MD Anderson Cancer Center. http://medicalxpress.com/news/2012-02-reformulated-imatinib-morphine-tolerance-lab.html Medications Tue, 21 Feb 2012 10:06:47 EST news249041188 (AP) -- In a case that could affect India's role as drug provider to the developing world, the Supreme Court began hearing arguments Tuesday over whether the government had the right to deny a patent to Swiss drugmaker Novartis AG for its lifesaving cancer treatment Gleevec. http://medicalxpress.com/news/2011-09-novartis-patent-indian-court.html Medications Tue, 06 Sep 2011 10:22:55 EST news234523359 (Medical Xpress) -- Customizing targeted therapies to each tumor's molecular characteristics, instead of a one-size-fits-all approach by tumor type, may be more effective for some types of cancer, according to research conducted by The University of Texas MD Anderson Cancer Center. http://medicalxpress.com/news/2011-06-therapies-tumor-specific-gene-mutations.html Cancer Fri, 03 Jun 2011 14:28:40 EST news226330079 After decades of studying the pathological process that wipes out large volumes of memory, scientists at The Feinstein Institute for Medical Research discovered a molecule called c-Abl that has a known role in leukemia also has a hand in Alzheimer's disease. The finding, reported in the June 14th issue of the Journal of Alzheimer's Disease, offers a new target for drug development that could stave off the pathological disease process. http://medicalxpress.com/news/2011-05-protein-linked-alzheimer-disease.html Medical research Tue, 24 May 2011 15:47:09 EST news225470789 A study from Tufts Medical Center researchers published today finds that a novel drug shows promise for treating leukemia patients who have few other options because their disease has developed resistance to standard treatment. http://medicalxpress.com/news/2011-04-drug-potential-treatment-resistant-leukemia.html Cancer Mon, 11 Apr 2011 16:10:51 EST news221757042