http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Hair dye manufacturers are on notice: The cure for gray hair is coming. That's right, the need to cover up one of the classic signs of aging with chemical pigments will be a thing of the past thanks to a team of European researchers. In a new research report published online in The FASEB Journal people who are going gray develop massive oxidative stress via accumulation of hydrogen peroxide in the hair follicle, which causes our hair to bleach itself from the inside out, and most importantly, the report shows that this massive accumulation of hydrogen peroxide can be remedied with a proprietary treatment developed by the researchers described as a topical, UVB-activated compound called PC-KUS (a modified pseudocatalase). What's more, the study also shows that the same treatment works for the skin condition, vitiligo. http://medicalxpress.com/news/2013-05-gray-hair-vitiligo-reversed-root.html Medical research Fri, 03 May 2013 12:57:35 EST news286804531 The belief that nervous shock can cause you to go grey overnight (medically termed canities subita) is one of those tales which could nearly be true. There are certainly cases in medical literature of rapid greying over quite short periods of time. And reported cases go back to antiquity including such legendary figures as Thomas More and Marie Antoinette. http://medicalxpress.com/news/2013-02-medical-myth-stress-hair-greyovernight.html Health Wed, 27 Feb 2013 09:10:01 EST news281178027 Our DNA, which stores our genetic information, is constantly exposed to damage. If not properly repaired, DNA damage can lead to cell death. This, in turn, can lead to tissue exhaustion and ageing, or induce mutations resulting in uncontrolled cell proliferation and cancer. Brca1 is a key gene that mediates DNA repair, and mutations in Brca1 lead to familial and sporadic breast and ovarian cancer in humans. http://medicalxpress.com/news/2013-01-uncover-role-brca1-survival-skin.html Cancer Thu, 03 Jan 2013 07:59:49 EST news276422333 For years researchers have been trying to identify the molecular changes that occur in tumour-initiating cells from the very first oncogenic mutation to the development of invasive tumors. The most frequently diagnosed skin cancer in humans is basal cell carcinoma, with over a million such cases reported each year. An EU-funded team of researchers led by Prof. Cédric Blanpain of the Université libre de Bruxelles (ULB) has identified the molecular events that occur during basal cell carcinoma initiation. This study was recently published in the journal Nature Cell Biology and it was partially supported by the European Research Council (ERC) Starting Grant worth EUR 1.6 million awarded to Prof. Blanpain. http://medicalxpress.com/news/2012-12-scientists-uncover-cells-basal-cell.html Cancer Fri, 21 Dec 2012 06:36:54 EST news275294208 Johns Hopkins scientists have created stunning images of the branching patterns of individual sensory nerve cells. Their report, published online in the journal eLife on Dec. 18, details the arrangement of these branches in skin from the backs of mice. The branching patterns define ten distinct groups that, the researchers say, likely correspond to differences in what the nerves do and could hold clues for pain management and other areas of neurological study. http://medicalxpress.com/news/2012-12-braille-scientists-sensory-nerves-mouse.html Medical research Wed, 19 Dec 2012 16:21:37 EST news275156489 One of the most outstanding and unresolved questions in cancer biology is the identification of cells at the origin of cancer and the understanding of the molecular changes that occur in tumor initiating cells from the first oncogenic mutation to the development of invasive cancer. Basal cell carcinoma (BCC) is the most frequent cancer in human with more than million of new patients diagnosed each year with BCCs. Recently, the group of Pr. Cédric Blanpain uncovered the cells at the origin of BCC (Youssef et al, Nature Cell Biology, 2010). http://medicalxpress.com/news/2012-11-uncover-molecular-mechanisms-basal-cell.html Cancer Mon, 26 Nov 2012 09:40:01 EST news273144152 Turns out the same glands that make you sweat are responsible for another job vital to your health: they help heal wounds. http://medicalxpress.com/news/2012-11-glands-major-role-human-wounds.html Medical research Tue, 20 Nov 2012 10:15:54 EST news272628941 Finding a way to restore hair growth after substantial hair loss is something of an obsession worldwide. Investigators at the Society of Nuclear Medicine's 2012 Annual Meeting presented how stem cell research for the development of new hair follicles can be monitored with an optical imaging technique that uses bioluminescence, the same process that allows fireflies to light up. http://medicalxpress.com/news/2012-06-bioluminescence-imaging-stem-cell-therapy.html Medical research Mon, 11 Jun 2012 14:10:01 EST news258639369 (HealthDay) -- Patients with pityriasis versicolor (PV) lesions may experience hair thinning and/or loss within the lesion, according to a study published online May 10 in the Journal of the American Academy of Dermatology. http://medicalxpress.com/news/2012-05-hair-loss-pathology-pityriasis-versicolor.html Diseases, Conditions, Syndromes Wed, 23 May 2012 05:20:01 EST news256966469 Japanese researchers have successfully grown hair on hairless mice by implanting follicles created from stem cells, they announced Wednesday, sparking new hopes of a cure for baldness. http://medicalxpress.com/news/2012-04-japan-baldness.html Medical research Wed, 18 Apr 2012 11:02:42 EST news253965731 (Medical Xpress) -- A research team including University of Wyoming neurobiologist Jeff Woodbury has discovered a new technique to determine how the touch sensory system is organized in hairy skin, providing a new understanding of the sense of touch. http://medicalxpress.com/news/2012-04-scientists-breakthrough.html Neuroscience Mon, 02 Apr 2012 07:20:11 EST news252570001 Researchers from the Perelman School of Medicine at the University of Pennsylvania have identified an abnormal amount a protein called Prostaglandin D2 in the bald scalp of men with male pattern baldness, a discovery that may lead directly to new treatments for the most common cause of hair loss in men. In both human and animal models, researchers found that a prostaglandin known as PGD2 and its derivative, 15-dPGJ2, inhibit hair growth. The PGD2-related inhibition occurred through a receptor called GPR44, which is a promising therapeutic target for androgenetic alopecia in both men and women with hair loss and thinning. The study is published in Science Translational Medicine. http://medicalxpress.com/news/2012-03-inhibitor-male-pattern-baldness-hair-loss.html Medical research Wed, 21 Mar 2012 14:00:10 EST news251555744 Compared to our other senses, scientists don't know much about how our skin is wired for the sensation of touch. Now, research reported in the December 23rd issue of the journal Cell provides the first picture of how specialized neurons feel light touches, like a brush of movement or a vibration, are organized in hairy skin. http://medicalxpress.com/news/2011-12-skin-wired.html Neuroscience Thu, 22 Dec 2011 12:00:03 EST news243777381 Hair follicle keratinocytes offer a simple and accessible route to generate patient-specific induced pluripotent stem cells, iPSCs, with minimum inconvenience for the patients, shows study presented at the ESC Congress 2011 today. http://medicalxpress.com/news/2011-08-hair-cell-derived-patient-specific-heart-cells-disease.html Cardiology Mon, 29 Aug 2011 10:14:30 EST news233831654 A new study by researchers at NYU Langone Medical Center has shown that, for the first time, Wnt signaling, already known to control many biological processes, between hair follicles and melanocyte stem cells can dictate hair pigmentation. The study was published in the June 11, 2011 issue of the journal Cell. http://medicalxpress.com/news/2011-06-clues-hair-gray.html Medical research Tue, 14 Jun 2011 11:04:51 EST news227268282 In one of the first studies to look at the population behavior of a large pool of stem cells in thousands of hair follicles – as opposed to the stem cell of a single hair follicle – Keck School of Medicine of USC scientists deciphered how hair stem cells in mice and rabbits can communicate with each other and encourage mutually coordinated regeneration, according to an article published in the April 29 edition of the journal Science. http://medicalxpress.com/news/2011-05-reveals-clues-hair-stem-cell.html Medical research Mon, 09 May 2011 09:31:43 EST news224152258 (Medical Xpress) -- Restoration Robotics Inc., a privately-held medical device company which is based in California, has received FDA approval for their ARTAS System. The ARTAS System, which is designed to harvest the hair follicles from the scalp of men who have been diagnosed with androgenetic alopecia, a condition that is more commonly known as male pattern hair loss, in men who also have black or brown straight hair, has received its 510K clearance from the Food & Drug Administration. http://medicalxpress.com/news/2011-04-hair-loss-robot-gains-fda.html Medical research Tue, 26 Apr 2011 13:46:36 EST news223044379