http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. (HealthDay)—Children with diabetes-associated autoantibodies have alterations in the gut microbiome, according to a study published in the April issue of Diabetes. http://medicalxpress.com/news/2013-04-diabetes-linked-autoantibodies-children-gut-microbes.html Diabetes Sat, 06 Apr 2013 06:10:01 EST news284445780 University of Michigan research sheds new light on why certain people are more likely to suffer from rheumatoid arthritis – paving the way to explore new treatments for both arthritis and other autoimmune diseases. http://medicalxpress.com/news/2013-01-uncover-gene-role-rheumatoid-arthritis.html Arthritis & Rheumatism Thu, 24 Jan 2013 11:06:58 EST news278248007 Researchers have identified four new regions on the human genome associated with Behcet's disease, a painful and potentially dangerous condition found predominantly in people with ancestors along the Silk Road. For nearly 2,000 years, traders used this 4,000-mile network linking the Far East with Europe to exchange goods, culture and, in the case of the Silk Road disease, genes. National Institutes of Health researchers and their Turkish and Japanese collaborators published their findings in the Jan. 6, 2013, advance online issue of Nature Genetics. http://medicalxpress.com/news/2013-01-genetic-mystery-behcet-disease-unfolds.html Genetics Sun, 06 Jan 2013 13:00:09 EST news276685053 Japanese researchers at the RIKEN Center for Genomic Medicine (CGM) and their colleagues have identified 8 new loci associated with susceptibility to atopic dermatitis in the Japanese population. The findings, which appear in the journal Nature Genetics, advance our understanding of the genetic basis of the skin disorder, which affects millions of children and adults around the world. http://medicalxpress.com/news/2012-10-genome-wide-susceptibility-loci-atopic-dermatitis.html Genetics Sun, 07 Oct 2012 13:58:36 EST news268837101 (HealthDay)—Patients with acute myeloid leukemia who receive a stem cell transplant from a donor with activating killer-cell immunoglobulin-like receptor (KIR) genotype KIR2DS1, which has ligand specificity for human leukocyte antigen (HLA)-C2 antigen, have a lower rate of relapse, according to a study published in the Aug. 30 issue of the New England Journal of Medicine. http://medicalxpress.com/news/2012-08-donor-genotype-lowers-leukemia-relapse.html Cancer Thu, 30 Aug 2012 10:30:02 EST news265540433 (HealthDay) -- Following a conditioning regimen of lymphoid irradiation (TLI) and antithymocyte globulin (ATG), the majority of HLA-matched kidney and hematopoietic cell transplant recipients can be withdrawn from immunosuppressive drugs, according to a small study published online March 8 in the American Journal of Transplantation. http://medicalxpress.com/news/2012-03-conditioning-regimen-beneficial-kidney-recipients.html Surgery Wed, 28 Mar 2012 18:08:10 EST news252176882 (HealthDay) -- A novel approach using a bioengineered mobilized cellular product enriched with hematopoietic stem cells (HSCs) and tolerogenic graft facilitating cells (FCs) in combination with nonmyeloablative conditioning is safe and practical for inducing immune tolerance after transplantation, according to a study published in the March 7 issue of Science Translational Medicine. http://medicalxpress.com/news/2012-03-stem-cells-conditioning-immune-tolerance.html Immunology Thu, 08 Mar 2012 16:20:01 EST news250442462 Avoiding HLA-DR mismatching appears to be beneficial in pediatric kidney transplant patients, however the likelihood of finding a matching donor must be considered against the wait time for a possible donation, according to a report in the July issue of Archives of Surgery. http://medicalxpress.com/news/2011-07-factors-pediatric-kidney-transplant.html Other Mon, 18 Jul 2011 16:40:04 EST news230225991