http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. GPs could more accurately predict the likely progression of disease in patients with musculoskeletal conditions by asking them a simple set of generic questions during their very first consultation, new research funded by Arthritis Research UK has shown. http://medicalxpress.com/news/2013-06-simple-prognostic-tool-gps-accurately.html Health Wed, 12 Jun 2013 08:52:54 EST news290245960 (Medical Xpress)—Regular use of cholesterol-lowering medicines calledstatins may reduce a person's chances of developing the degenerative joint disease osteoarthritis, UK scientists have found. http://medicalxpress.com/news/2013-05-statin-therapy-osteoarthritis.html Arthritis & Rheumatism Thu, 30 May 2013 06:22:17 EST news289113726 Using the Department of Defense Serum Repository (DoDSR), University of Cincinnati (UC) researchers have identified a number of biomarkers for inflammatory bowel disease (IBD), which could help with earlier diagnosis and intervention in those who have not yet shown symptoms. http://medicalxpress.com/news/2013-05-biomarkers-inflammatory-bowel-disease.html Diseases, Conditions, Syndromes Tue, 21 May 2013 17:21:31 EST news288375680 A gas associated with the smell of rotten eggs has proven to effectively reduce joint swelling, in research which could lead to advances in the treatment of arthritis. http://medicalxpress.com/news/2013-04-foul-smelling-gas-health-benefits-joint.html Arthritis & Rheumatism Mon, 29 Apr 2013 12:51:29 EST news286458682 Depression may inhibit the anti-inflammatory effects typically associated with physical activity and light-to-moderate alcohol consumption, according to researchers at Duke Medicine. http://medicalxpress.com/news/2013-03-people-depression-reap-full-benefits.html Psychology & Psychiatry Tue, 26 Mar 2013 12:29:47 EST news283519780 (Medical Xpress)—New research from UC Davis published in the Proceedings of the National Academy of Sciences shows that blocking an enzyme that promotes inflammation can prevent the tissue damage following a heart attack that often leads to heart failure. http://medicalxpress.com/news/2013-03-blocking-inflammation-pathway-cardiac-fibrosis.html Medical research Fri, 22 Mar 2013 11:10:05 EST news283167535 Existing mouse models do not appear to accurately reproduce the human genomic response to serious traumatic injury, including major burns, according to an article appearing in PNAS Early Edition. http://medicalxpress.com/news/2013-02-mouse-inflammatory-genomic-response-injuries.html Inflammatory disorders Mon, 11 Feb 2013 15:00:01 EST news279804831 (Medical Xpress)—Researchers have identified a complex of proteins that promotes the growth of some types of colon and gastric cancers, and shown that medications that block the function of this complex have the potential to be developed into a new treatment for these diseases. http://medicalxpress.com/news/2013-01-potential-treatment-gastrointestinal-cancers.html Cancer Thu, 17 Jan 2013 06:14:19 EST news277625649 People suffering from chronic inflammatory conditions, such as rheumatoid arthritis, inflammatory bowel disease and asthma—in which psychological stress plays a major role—may benefit from mindfulness meditation techniques, according to a study by University of Wisconsin-Madison neuroscientists with the Center for Investigating Healthy Minds at the Waisman Center. http://medicalxpress.com/news/2013-01-mindfulness-meditation-relieve-chronic-inflammation.html Immunology Wed, 16 Jan 2013 16:47:59 EST news277577269 Three per cent of the world's population suffer from the skin condition known as psoriasis. A Norwegian research-based company is close to developing a treatment that could help millions. The research may also prove beneficial in the treatment of other illnesses. http://medicalxpress.com/news/2013-01-revolutionary-treatment-psoriasis.html Diseases, Conditions, Syndromes Fri, 11 Jan 2013 14:45:04 EST news277137898 When different types of cells are transplanted with the intent of having them aid in repairing central nervous system (CNS) trauma, what is the fate and function of those cells? A Belgian research team carried out research aimed at answering this question by determining how five varieties of cells - neural stem cells, mouse embryonic fibroblasts, dendritic cells, bone marrow mononuclear cells (BMMNCs) and splenocytes - functioned and survived after transplantation in the CNS. http://medicalxpress.com/news/2012-12-fate-function-cells-transplanted-cns.html Medical research Thu, 20 Dec 2012 17:19:57 EST news275246338 (Medical Xpress)—Results of new research from the University of Adelaide are a promising step forward in helping to improve the quality of life-saving blood transfusions for preterm babies, by reducing the likelihood of adverse inflammatory responses to the blood. http://medicalxpress.com/news/2012-11-efficacy-blood-transfusions-preterm-babies.html Pediatrics Thu, 22 Nov 2012 08:40:03 EST news272795237 Imagine a world where you could never dine away from home, wear makeup, smell of sweet perfumes or eat a large percentage of food on store shelves. According to allergists at the American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting that is kicking off today in Anaheim, Calif., that is the world for 2 to 3 percent of individuals living with a spice allergy. http://medicalxpress.com/news/2012-11-spice-allergy-sugar-nice.html Immunology Thu, 08 Nov 2012 03:00:21 EST news271566003 Research just carried out in the Immunology Research Centre, led by Dr James Harris, based in the School of Biochemistry and Immunology, Trinity College Dublin, shows that the process of autophagy  regulates the production of inflammatory molecules and may therefore represent an effective target for the development of new anti-inflammatory therapeutics. The findings have been recently published online in the Journal of Immunology. http://medicalxpress.com/news/2012-10-important-role-autophagy-self-eating-cells.html Medical research Wed, 24 Oct 2012 10:00:01 EST news270286150 Patients newly diagnosed with pediatric Crohn's disease had significantly different levels of certain types of bacteria in their intestinal tracts than age-matched controls, according to a paper in the October Journal of Clinical Microbiology. The work may ultimately lead to treatment involving manipulation of the intestinal bacteria. http://medicalxpress.com/news/2012-10-specific-bacterial-species-crohn.html Diseases, Conditions, Syndromes Mon, 22 Oct 2012 14:32:13 EST news270135115 Researchers at NYU School of Medicine have discovered the protein product of a little-known gene may one day prove useful in identifying and monitoring the development of mesothelioma in early stages, when aggressive treatment can have an impact on the progression of disease and patient prognosis. http://medicalxpress.com/news/2012-10-high-blood-based-protein-specific-mesothelioma.html Cancer Wed, 10 Oct 2012 17:00:24 EST news269103854 (Medical Xpress)—Researchers at King's have established a significant link between asthma and an immune response called 'Th17', previously only attributed to inflammatory conditions such as multiple sclerosis. http://medicalxpress.com/news/2012-08-reveals-link-asthma.html Immunology Thu, 23 Aug 2012 08:49:34 EST news264930563 Use of tumor necrosis factor (TNF) inhibitors for treatment of psoriasis is associated with a significantly reduced risk for heart attack (myocardial infarction) compared to other forms of treatment, according to a report published Online First by Archives of Dermatology. http://medicalxpress.com/news/2012-08-heart-psoriasis-treatments.html Diseases, Conditions, Syndromes Mon, 20 Aug 2012 16:00:07 EST news264692845 Millions of people around the world are prescribed glucocorticoids for a wide variety of inflammatory conditions, including, rheumatoid arthritis, asthma and inflammatory bowel diseases. Although they are effective and widely used, one of the potentially serious side effects of these medications is glucocorticoid-induced osteoporosis. http://medicalxpress.com/news/2012-03-oral-glucocorticoids-months-longer-beware.html Diseases, Conditions, Syndromes Tue, 27 Mar 2012 10:00:12 EST news252061197 Sepsis, a form of systemic inflammation, is the leading cause of death in critically ill patients. Sepsis is linked with massive cell death; however, the specific mechanisms involved in the lethality of sepsis are unclear. Now, a new study published by Cell Press in the December 23rd issue of the journal Immunity finds that inhibition of a specific cell death pathway called "necroptosis" protected mice from lethal inflammation. The research may lead to new therapeutic interventions for fatal inflammatory conditions that are notoriously hard to control. http://medicalxpress.com/news/2011-12-scientists-cell-death-pathway-involved.html Medical research Thu, 22 Dec 2011 12:00:08 EST news243777561 Researchers have discovered a cellular pathway that promotes inflammation in diseases like asthma, rheumatoid arthritis, psoriasis, inflammatory bowel disease, and multiple sclerosis. Understanding the details of this pathway may provide opportunities for tailored treatments of inflammatory and autoimmune diseases. http://medicalxpress.com/news/2011-10-inflammatory-autoimmune-diseases.html Inflammatory disorders Fri, 07 Oct 2011 12:10:45 EST news237208178 A new study from Rhode Island Hospital researchers suggests that controlling cholesterol may be important for heart health in patients who are taking non-steroidal anti-inflammatory drugs (NSAIDs) such as naproxen. The findings are based on a study on the safety of NSAID medications in clinically relevant animal models when high cholesterol is a factor. The study is published in the current issue of the journal Surgery. http://medicalxpress.com/news/2011-09-cardiovascular-nsaid.html Cardiology Mon, 26 Sep 2011 12:22:54 EST news236258556 Researchers at King's College London have found a molecule in the body which controls sensitivity to pain from UVB irradiation, identifying it as a new target for medicines to treat pain caused by other common inflammatory conditions such as arthritis. http://medicalxpress.com/news/2011-07-discovery-sunburn-pain-relief-inflammatory.html Medical research Wed, 06 Jul 2011 15:03:49 EST news229183399 Individuals with systemic inflammatory conditions, such as rheumatoid arthritis (RA) and psoriasis, experience a 1.5 to 2-fold increased rate of cardiovascular disease. Previous research suggests that inflammation and insulin resistance, linked with these conditions, likely accelerate the development of cardiovascular risk and diabetes. Researchers at Brigham and Women's Hospital (BWH) sought to determine whether commonly used disease-modifying antirheumatic drugs (DMARDs), which are directed against inflammation, might reduce the risk for developing diabetes in patients with RA or psoriasis. They found that among patients with RA or psoriasis, the risk for developing diabetes was lower for those patients who started TNF inhibitor or hydroxychloroquine. Their findings are published in the June 22/29, 2011 issue of the Journal of the American Medical Association. http://medicalxpress.com/news/2011-06-common-rheumatoid-arthritis-psoriasis-medications.html Diseases, Conditions, Syndromes Tue, 21 Jun 2011 16:23:21 EST news227892119