http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Australian scientists have charted the path of insulin action in cells in precise detail like never before. This provides a comprehensive blueprint for understanding what goes wrong in diabetes. http://medicalxpress.com/news/2013-05-insight-dazzling-impact-insulin-cells.html Medical research Tue, 21 May 2013 11:25:38 EST news288354330 (Medical Xpress)—The mystery of why some people get fat eating high-fat foods while others can stay skinny on a diet of burgers and chips is closer to being solved. http://medicalxpress.com/news/2013-05-mouse-clue-skinny-high-fat-diet.html Diabetes Wed, 01 May 2013 08:50:02 EST news286616255 Living against the clock—working late-night shifts or eating at inappropriate times, for example—can come with real health risks, metabolic syndrome, obesity, and diabetes among them. Now, researchers reporting in Current Biology, a Cell Press publication, on February 21 have new evidence to explain why it matters not just what mice (or by extension, people) eat, but also when they eat it. http://medicalxpress.com/news/2013-02-clock-risky-business.html Medical research Thu, 21 Feb 2013 12:51:26 EST news280673477 Disruption in the body's circadian rhythm can lead not only to obesity, but can also increase the risk of diabetes and heart disease. http://medicalxpress.com/news/2013-02-circadian-clock-linked-obesity-diabetes.html Medical research Thu, 21 Feb 2013 12:00:01 EST news280670192 (HealthDay)—Estrogen treatment at the time of surgical menopause may reverse aspects of pathway-selective insulin resistance in the liver associated with a high-fat diet (HFD) in mice by promoting insulin action on glucose metabolism but limiting hepatic lipid deposition, according to a study published in the February issue of Diabetes. http://medicalxpress.com/news/2013-02-estrogen-pathway-selective-insulin-resistance.html Diabetes Thu, 14 Feb 2013 14:08:33 EST news280073296 (Medical Xpress)—A nutritional supplement available over-the-counter may offer protection from Alzheimer's disease, a study by the University of Virginia and Northwestern University suggests. http://medicalxpress.com/news/2013-01-nutritional-supplement-alzheimer.html Alzheimer's disease & dementia Thu, 10 Jan 2013 06:12:46 EST news277020757 (HealthDay)—In elderly individuals without type 2 diabetes, high levels of fetuin-A, a protein that inhibits arterial calcification and insulin action, is associated with a lower risk of cardiovascular disease, according to a study published online Dec. 18 in Diabetes Care. http://medicalxpress.com/news/2013-01-fetuin-a-linked-cardiovascular-disease.html Diabetes Tue, 08 Jan 2013 14:20:01 EST news276874379 All cells need glucose (sugar) to produce the energy they need to survive. High glucose levels in the bloodstream (such as occur after a meal), trigger the pancreas to produce insulin. In turn, muscle and fat cells respond to insulin by moving GLUT4, a glucose transporter, from intracellular storage out to the cell surface. There, GLUT4 can take up the glucose the cell needs from the bloodstream. http://medicalxpress.com/news/2011-09-glucose-uptake-newly-protein.html Medical research Tue, 06 Sep 2011 12:21:51 EST news234530490 Researchers at the Joslin Diabetes Center have shown that an enzyme found in the mitochondria of cells is decreased in the skeletal muscle of those with diabetes, a finding that could lead to the development of drugs to boost the activity of this enzyme in an effort to fight the disease. http://medicalxpress.com/news/2011-08-treatment-diabetes-prediabetes.html Medical research Mon, 22 Aug 2011 15:25:48 EST news233245537 A Yale University-led research team has discovered how reduced expression of a particular gene protects against obesity and type 2 diabetes, possibly prolonging lifespan by mimicking the effects of calorie restriction. The study appears in the August 3 issue of Cell Metabolism. http://medicalxpress.com/news/2011-08-mimicking-calorie-restriction-obesity-diabetes.html Medical research Wed, 03 Aug 2011 14:20:01 EST news231598858