http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Working night shifts might increase the risk of developing ovarian cancer, indicates research published in Occupational and Environmental Medicine. http://medicalxpress.com/news/2013-03-night-shifts-linked-ovarian-cancer.html Cancer Thu, 14 Mar 2013 18:30:01 EST news282498591 (HealthDay)—The latest U.S. cancer statistics find that 1.5 million new cases of invasive cancer were diagnosed among Americans in 2009, with more men than women developing malignancies and blacks at higher risk for cancer than whites. http://medicalxpress.com/news/2013-02-cancer-vary-widely-state-cdc.html Cancer Thu, 21 Feb 2013 19:00:02 EST news280691732 Early laboratory tests are the first to successfully use an experimental molecular therapy to block a hard-to-target part of a protein complex linked to several types of invasive cancer. http://medicalxpress.com/news/2013-02-molecular-inhibitors-successfully-difficult-cancer.html Cancer Tue, 05 Feb 2013 09:45:59 EST news279279861 The best approach to detecting cervical cancer in HIV-positive women living in research limited countries such as those in Sub-Saharan Africa combines commonly used testing methods tailored to local levels of development and medical infrastructure, according to a study by researchers from and the University of Witwatersrand in South Africa and the University of North Carolina. http://medicalxpress.com/news/2013-01-cervical-cancer-screening-less-developed-areas.html Cancer Mon, 14 Jan 2013 09:09:43 EST news277376977 (HealthDay)—Younger women with aggressive breast cancers often benefit more than older women when they undergo early, pre-operative chemotherapy, a new study finds. http://medicalxpress.com/news/2012-12-aggressive-breast-cancer-chemo-young.html Cancer Thu, 06 Dec 2012 16:10:03 EST news274030465 One of the most outstanding and unresolved questions in cancer biology is the identification of cells at the origin of cancer and the understanding of the molecular changes that occur in tumor initiating cells from the first oncogenic mutation to the development of invasive cancer. Basal cell carcinoma (BCC) is the most frequent cancer in human with more than million of new patients diagnosed each year with BCCs. Recently, the group of Pr. Cédric Blanpain uncovered the cells at the origin of BCC (Youssef et al, Nature Cell Biology, 2010). http://medicalxpress.com/news/2012-11-uncover-molecular-mechanisms-basal-cell.html Cancer Mon, 26 Nov 2012 09:40:01 EST news273144152 The stiffness of breast tissue is increasingly recognized as an important factor explaining the onset of breast cancer. Stiffening induces molecular changes that promote cancerous behavior in cells. Bioengineering studies have found that breast cancer cells grown on a 3-D gel have enhanced cell replication and decreased organization as rigidity increases. These signals are probably coordinated by surface proteins that communicate with connective tissue, to regulate cell replication, death, and movement. However, very little is known about how stiffness or other physical characteristics of tissues contributes to cancer behavior in living animals. http://medicalxpress.com/news/2012-09-tension-gut-muscles-cell-invasion.html Cancer Fri, 07 Sep 2012 17:01:13 EST news266256043 One in five women with breast cancer who opt for breast conserving surgery rather than a mastectomy have a reoperation, according to a national study published in the British Medical Journal today. This information on the risk of reoperation should help women in making the decision about whether to undergo breast conserving surgery or mastectomy. http://medicalxpress.com/news/2012-07-women-breast-cancer-reoperation-surgery.html Cancer Thu, 12 Jul 2012 18:30:01 EST news261309000 Long-term cancer survivors take sick leave more often than their disease-free colleagues, suggesting that they struggle at work despite their ability to work five years after diagnosis. These findings by Steffen Torp, from Vestfold University College in Norway, and colleagues is published online in Springer's Journal of Cancer Survivorship. http://medicalxpress.com/news/2012-06-long-term-cancer-survivors-struggle-regular.html Cancer Tue, 19 Jun 2012 11:10:22 EST news259323011 More than one third of patients with invasive cancer are undertreated for their pain, with minorities twice as likely to not receive analgesics, according to research from The University of Texas MD Anderson Cancer Center. http://medicalxpress.com/news/2012-04-cancer-pain-undertreated.html Cancer Mon, 16 Apr 2012 17:36:07 EST news253816302 Radiotherapy treatment (RT) after surgery for ductal carcinoma in situ (DCIS) still has a major protective effect against recurrence more than 15 years later, according to the results of an international trial. Researchers found that the use of RT in addition to surgery could reduce the chances of a local recurrence (the cancer coming back in the same breast) by 50%. Results from the trial, which has one of the longest follow-ups of a large group of patients in the world to date, will be reported today to the 8th European Breast Cancer Conference (EBCC-8). http://medicalxpress.com/news/2012-03-radiotherapy-dcis-recurrence-years.html Cancer Thu, 22 Mar 2012 05:10:41 EST news251611826 The trefoil factor 3 (TFF3) protein protects and maintains the integrity of the epithelial surface in the normal breast. New research has found that while TFF3 protein expression is higher in well-differentiated low grade tumors and therefore associated with features of a good prognosis, it has a more sinister role in breast cancer invasion and metastasis. The report is published in the March issue of the American Journal of Pathology. http://medicalxpress.com/news/2012-02-protein-functions-breast-contribute-cancer.html Cancer Thu, 16 Feb 2012 05:20:01 EST news248590309 Researchers have discovered a restricted pattern of molecules that differentiate early-stage breast tumors from invasive, life-threatening cancer. They also found a similar molecular signature that correlated with the aggressiveness of invasive tumors, and with the time to metastasis and overall survival. http://medicalxpress.com/news/2012-02-early-breast-tumors-deadly-small.html Cancer Tue, 07 Feb 2012 17:00:04 EST news247854868 A mutant protein found in nearly all pancreatic cancers plays a role not only in the cancer's development but in its continued growth, according to a new study from University of Michigan Comprehensive Cancer Center researchers. The finding suggests a possible target for developing new ways to treat this deadly disease. http://medicalxpress.com/news/2012-01-gene-linked-pancreatic-cancer-growth.html Cancer Tue, 31 Jan 2012 11:08:43 EST news247230516 Researchers at the Perelman School of Medicine at the University of Pennsylvania report that a short course of vaccination with an anti-HER2 dendritic cell vaccine made partly from the patient's own cells triggers a complete tumor eradication in nearly 20 percent of women with ductal carcinoma in situ (DCIS), an early breast cancer. More than 85 percent of patients appear to have a sustained immune response after vaccination, which may reduce their risk of developing a more invasive cancer in the future. The results of the study were published online this month of Cancer and in the January issue of the Journal of Immunotherapy. http://medicalxpress.com/news/2012-01-four-week-vaccination-regimen-early-breast.html Cancer Mon, 30 Jan 2012 16:50:01 EST news247163863 Metastasizing cancer cells often express integrins that provide better traction. A new study in The Journal of Cell Biology reveals how a lipid-converting enzyme helps the cells mobilize these integrins. http://medicalxpress.com/news/2012-01-dgk-alpha-cancer-cells-gain-traction.html Cancer Mon, 23 Jan 2012 13:16:08 EST news246546961 A new study suggests some women needing a lumpectomy or mastectomy to treat their breast cancer have another potential option that is safe and effective, say researchers at Georgetown. They say the procedure known as a nipple sparing mastectomy is also a viable surgical option for women who choose to have their breasts removed because of their increased risk of developing the disease. For both groups of women, the surgery offers a chance for a more natural looking and normal feeling reconstructed breast as compared to other forms of mastectomy. http://medicalxpress.com/news/2011-10-1050esearchers-year-series-nipple-mastectomy.html Cancer Thu, 27 Oct 2011 03:44:52 EST news238905884 Amid the controversy surrounding the Food and Drug Administration's ruling that Avastin should no longer be used to treat metastatic breast cancer, a new multinational Phase III clinical trial shows that Avastin significantly increased tumor response rates in breast cancer patients when given before surgery. http://medicalxpress.com/news/2011-08-clinical-trial-benefit-adding-avastin.html Cancer Tue, 23 Aug 2011 12:47:04 EST news233321197 A study at UCLA's Jonsson Comprehensive Cancer Center found that nearly all patients with high-grade, non-invasive bladder cancer are not receiving the guideline-recommended care that would best protect them from recurrence, a finding that researchers characterized as alarming. http://medicalxpress.com/news/2011-07-bladder-cancer-patients-rarely.html Cancer Mon, 11 Jul 2011 04:14:27 EST news229576437 Cancer and chronic inflammation are partners in peril, with the latter increasing the likelihood that malignant tumors will develop, grow and spread. Researchers at the University of California, San Diego School of Medicine say they've identified a tumor inflammation trigger that is common to most, if not all, cancers. And using existing inhibitory drugs, the scientists were able to dramatically decrease primary tumor growth in animal studies and, more importantly, halt tumor progression and metastasis. http://medicalxpress.com/news/2011-06-stifling-growth-cancer.html Cancer Mon, 13 Jun 2011 13:16:08 EST news227189756 A new, promising marker for diagnosing prostate cancer has been discovered by Swedish researchers with the aid of a unique method developed at the Department of Immunology, Genetics and Pathology. The study, being published this week in the journal Proceedings of the National Academy of Sciences, PNAS, can lead to more reliable diagnoses and fewer unnecessary operations. http://medicalxpress.com/news/2011-05-marker-reliable-prostate-cancer.html Cancer Mon, 09 May 2011 15:00:38 EST news224161418