http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. The presence of posttraumatic stress disorder is significantly associated with the development of type 2 diabetes. This is the finding of scientists from the Helmholtz Zentrum München and the University Hospital Gießen and Marburg who worked with data from the population-based KORA cohort study. A sustained activation of the hormonal stress axis due to chronic stress symptoms is most likely a major causing mechanism. The scientists have published their results in the Journal of Psychosomatic Research. http://medicalxpress.com/news/2013-05-posttraumatic-stress-disorder-diabetes.html Psychology & Psychiatry Thu, 16 May 2013 10:50:02 EST news287919593 (Medical Xpress)—A protein associated with conditions of metabolic imbalance, such as diabetes and obesity, may play a role in the development of aggressive forms of breast cancer, according to new findings by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, and their colleagues. Metabolic imbalance is often caused by elevated carbohydrate intake, which can lead to over-activating a molecule called C-terminal binding protein (CtBP). This over-activation, in turn, can increase the risk of breast cancer. Results of their work appeared in Nature Communications, Feb. 5, 2013. http://medicalxpress.com/news/2013-02-scientists-molecular-link-metabolism-breast.html Cancer Wed, 06 Feb 2013 08:35:34 EST news279362125 (HealthDay)—Grape polyphenol (PP) supplementation prevents fructose-induced oxidative stress and insulin resistance in healthy volunteers with high metabolic risk, according to research published online Dec. 28 in Diabetes Care. http://medicalxpress.com/news/2013-02-grape-polyphenols-counteract-fructose-induced-effects.html Diabetes Mon, 04 Feb 2013 05:10:01 EST news279175097 (Medical Xpress)—Neural stem cells in the adult brain boost their levels of lipid metabolism to grow and generate new neurons. This new finding may open novel therapeutic avenues to treat age- or disease-associated loss of brain cells. http://medicalxpress.com/news/2012-12-lipid-metabolism-adult-neural-stem.html Medical research Tue, 04 Dec 2012 06:23:02 EST news273824574 (Medical Xpress)—New research has found that a type of anti-tumour immune cell protects against obesity and the metabolic syndrome that leads to diabetes. Results showing that immune cells known to be protective against malignancy called invariant natural killer T-cells (iNKT), that are lost when humans become obese, but can be restored through weight loss, have been published online this week in the journal Immunity. Marie Curie Fellow, Lydia Lynch at Trinity College Dublin, Ireland made the discovery and as first author in collaboration with colleagues at Harvard-affiliated Beth Israel Deaconess Medical Centre, and St Vincent's University Hospital have shown that therapies that activate iNKT cells could help manage obesity, diabetes, and metabolic disease. http://medicalxpress.com/news/2012-10-scientists-immune-cells-obesity.html Immunology Mon, 01 Oct 2012 18:59:42 EST news268336763 Invariant natural killer T-cells (iNKT) are a unique subset of immune cells that are known to influence inflammatory responses. Now, a scientific team led by researchers at Beth Israel Deaconess Medical Center (BIDMC) has found that iNKT cells play a protective role in guarding against obesity and the metabolic syndrome, a major consequence of obesity. http://medicalxpress.com/news/2012-09-natural-killer-t-cells-fat-tissue.html Immunology Thu, 13 Sep 2012 12:58:07 EST news266759879 Compared to normal cells, cancer cells have a prodigious appetite for glucose, the result of a shift in cell metabolism known as aerobic glycolysis or the "Warburg effect." Researchers focusing on this effect as a possible target for cancer therapies have examined how biochemical signals present in cancer cells regulate the altered metabolic state. http://medicalxpress.com/news/2012-06-glucose-deprivation-feedback-loop-cancer.html Cancer Tue, 26 Jun 2012 14:08:55 EST news259938526 The metabolic state of glioma stem cells, which give rise to deadly glioblastomas, is significantly different from that of the brain cancer cells to which they give birth, a factor which helps those stem cells avoid treatment and cause recurrence later. http://medicalxpress.com/news/2011-09-metabolic-state-brain-cancer-stem.html Cancer Tue, 06 Sep 2011 16:43:16 EST news234546183