http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Stem cells of the aging bone marrow recycle their own molecules to survive and keep replenishing the blood and immune systems as the body ages, researchers at UC San Francisco (UCSF) have discovered. http://medicalxpress.com/news/2013-02-stem-cell-survival-strategy-key.html Medical research Thu, 14 Feb 2013 12:10:01 EST news279965984 Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, Reuben Shaw has wondered if drugs originally designed to treat metabolic diseases could also work against cancer. http://medicalxpress.com/news/2013-01-diabetes-drug-lung-cancer-patients.html Cancer Tue, 29 Jan 2013 10:06:14 EST news278676360 The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, as opposed to ones based on enzymes. Now, researchers have identified a class of p53 target genes and regulatory molecules that represent more promising therapeutic candidates. http://medicalxpress.com/news/2013-01-cancer-suppressor-gene-links-metabolism.html Cancer Sun, 13 Jan 2013 13:00:20 EST news277297188 Researchers have found new evidence that metabolic stress can increase the onset of atrial arrhythmias, such as atrial fibrillation (AF), a common heart condition that causes an irregular and often abnormally fast heart rate. The findings may pave the way for the development of new therapies for the condition which can be expected to affect almost one in four of the UK population at some point in their lifetime. http://medicalxpress.com/news/2013-01-common-heart-condition.html Cardiology Tue, 08 Jan 2013 09:17:14 EST news276859023 (Medical Xpress)—Scientists at the Keck School of Medicine of the University of Southern California (USC) have found evidence that liver mitochondria in mice adapt to become better metabolizers of alcohol and increase in number after chronic exposure, which may raise the potential for free radical damage associated with aging and cancer over time. http://medicalxpress.com/news/2012-12-liver-mitochondria-chronic-alcohol-mice.html Medical research Fri, 21 Dec 2012 09:43:33 EST news275305389 A molecule thought to limit cell proliferation also helps cancer cells survive during initial tumor formation and when the wayward cells spread to other organs in the body, researchers at the University of Illinois at Chicago College of Medicine have found. http://medicalxpress.com/news/2012-06-key-enzyme-roles-friend-foe.html Medical research Thu, 14 Jun 2012 08:55:53 EST news258882913 Excess nutrients, such as fat and sugar, don't just pack on the pounds but can push some cells in the body over the brink. Unable to tolerate this "toxic" environment, these cells commit suicide. http://medicalxpress.com/news/2011-07-culprits-cell-death-fat-sugar.html Medical research Tue, 05 Jul 2011 12:27:26 EST news229087626 An international research team led by Dr. Tak Mak, Director, The Campbell Family Institute for Breast Cancer Research at Princess Margaret Hospital (PMH), has discovered a new aspect of "metabolic transformation", the process whereby tumour cells adapt and survive under conditions that would kill normal cells. http://medicalxpress.com/news/2011-05-cancer-scientists-breast-cells-environmental.html Cancer Sun, 15 May 2011 11:38:25 EST news224678285