http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. A groundbreaking new study led by the University of Kentucky Markey Cancer Center's Dr. Peter Zhou found that triple-negative breast cancer cells are missing a key enzyme that other cancer cells contain—providing insight into potential therapeutic targets to treat the aggressive cancer. Zhou's study is unique in that his lab is the only one in the country to specifically study the metabolic process of triple-negative breast cancer cells. http://medicalxpress.com/news/2013-02-key-enzyme-aggressive-breast-cancer.html Cancer Thu, 28 Feb 2013 13:45:04 EST news281281484 After you eat, your liver switches from producing glucose to storing it. At the same time, a cellular signaling pathway known as the unfolded protein response (UPR) is transiently activated, but it is not clear how this pathway contributes to the liver's metabolic switch. http://medicalxpress.com/news/2012-12-factor-liver-metabolism.html Medical research Fri, 21 Dec 2012 12:00:08 EST news275306928 A Penn research team, led by Mitchell Lazar, MD, PhD, director of the Institute for Diabetes, Obesity, and Metabolism at the Perelman School of Medicine, University of Pennsylvania, reports in Nature Medicine that mice in which an enzyme called histone deacetylase 3 (HDAC3) was deleted had massively fatty livers, but lower blood sugar, and were thus protected from glucose intolerance and insulin resistance, the hallmark of diabetes. http://medicalxpress.com/news/2012-05-liver-fat-wake-up-blood-sugar.html Medical research Sun, 06 May 2012 13:00:23 EST news255508086