http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. A new study in the Journal of Parkinson's Disease shows for the first time the effects of α-Synuclein (α-syn) gene multiplication on mitochondrial function and susceptibility to oxidative stress in human tissue. Mitochondrial dysfunction has been frequently implicated in the neurodegenerative process that underlies Parkinson's disease, but the basis for this has not been fully understood. http://medicalxpress.com/news/2011-10-link-mitochondrial-dysfunction-alpha-synuclein-multiplication.html Diseases, Conditions, Syndromes Thu, 06 Oct 2011 18:00:01 EST news237129377 Pre-implantation genetic diagnosis (PGD) can give women at risk of passing on a mitochondrial DNA disorder to their offspring a good chance of being able to give birth to an unaffected child, a researcher told the annual conference of the European Society of Human Genetics today (Monday). Dr. Debby Hellebrekers, from Maastricht University Medical Centre, Maastricht, The Netherlands, said that the scientists' findings could have a considerable effect on preventing the transmission of mitochondrial diseases. http://medicalxpress.com/news/2011-05-pgd-birth-healthy-children-women.html Genetics Mon, 30 May 2011 07:58:27 EST news225961096 A human drug that both prevents and cures kidney failure in mice sheds light on disabling human mitochondrial disorders, and may represent a potential treatment in people with such illnesses. http://medicalxpress.com/news/2011-05-animal-results-pave-rare-mitochondrial.html Medical research Thu, 19 May 2011 11:03:15 EST news225021774 (Medical Xpress) -- Researchers have discovered the first real evidence of the 'mother's curse' and its connection to male infertility due to genetic mutations in mitochondria. Led by Dr. Damian Dowling from Monash University in Melbourne and Paolo Innocenti from Uppsala University, their breakthrough research has been recently published in Science. http://medicalxpress.com/news/2011-05-mothers-curse-linked-male-infertility.html Genetics Mon, 16 May 2011 11:04:41 EST news224762657 (Medical Xpress) -- Around one in 20 men is infertile, but despite the best efforts of scientists, in many cases the underlying causes of infertility have remained a mystery. New findings by a team of Australian and Swedish researchers, however, will go a long way towards explaining this mystery. http://medicalxpress.com/news/2011-05-breakthrough-male-infertility.html Medical research Fri, 13 May 2011 07:08:47 EST news224489295