http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. A new analysis has found that genetic alterations in a particular cellular pathway are linked with bladder cancer risk, recurrence, disease progression, and patient survival. Published early online in Cancer, a peer- reviewed journal of the American Cancer Society, the findings could help improve bladder cancer screening and treatment. http://medicalxpress.com/news/2013-03-genetic-linked-bladder-cancer-recurrence.html Cancer Mon, 25 Mar 2013 00:00:01 EST news283356945 A single dose of an investigational anti-inflammatory drug, inclacumab, reduced damage to heart tissue during angioplasty in a study presented today at the American College of Cardiology's 62nd Annual Scientific Session. http://medicalxpress.com/news/2013-03-drug-heart-angioplasty.html Cardiology Tue, 12 Mar 2013 10:36:46 EST news282303358 The skin is a human being's largest sensory organ, helping to distinguish between a pleasant contact, like a caress, and a negative sensation, like a pinch or a burn. Previous studies have shown that these sensations are carried to the brain by different types of sensory neurons that have nerve endings in the skin. Only a few of those neuron types have been identified, however, and most of those detect painful stimuli. Now biologists at the California Institute of Technology (Caltech) have identified in mice a specific class of skin sensory neurons that reacts to an apparently pleasurable stimulus. http://medicalxpress.com/news/2013-01-sensations-biologists-individual-neurons-skin.html Neuroscience Wed, 30 Jan 2013 15:04:59 EST news278780662 Washington State University researchers have lengthened their list of environmental toxicants that can negatively affect as many as three generations of an exposed animal's offspring. http://medicalxpress.com/news/2013-01-plastic-products-jet-fuel-exposures.html Genetics Thu, 24 Jan 2013 17:00:05 EST news278265053 Encouraging safety and efficacy data on novel and emerging therapies presented at the 54th Annual Meeting of the American Society of Hematology (ASH) signal an important step forward in the development of treatment strategies for patients with hard-to-treat leukemia, myeloma, and myelofibrosis. http://medicalxpress.com/news/2012-12-therapeutic-agents-patients-hard-to-treat-blood.html Cancer Sun, 09 Dec 2012 11:50:04 EST news274274478 Scientists at NYU Langone Medical Center have identified two genes involved in establishing the neuronal circuits required for breathing. They report their findings in a study published in the December issue of Nature Neuroscience. The discovery, featured on the journal's cover, could help advance treatments for spinal cord injuries and neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), which gradually kill neurons that control the movement of muscles needed to breathe, move, and eat. http://medicalxpress.com/news/2012-11-scientists-genetic-signature-vital-neurons.html Neuroscience Thu, 29 Nov 2012 13:36:21 EST news273418573 (HealthDay)—Patients with acute myeloid leukemia whose peripheral blood blasts clear in six days or less after chemotherapy have significantly better survival than patients whose peripheral blasts clear later, according to a study published in the Nov. 1 issue of Cancer. http://medicalxpress.com/news/2012-10-prognosis-early-blast-clearance-leukemia.html Cancer Wed, 24 Oct 2012 16:20:04 EST news270313432 Cancers arise in the body all the time. Most are nipped in the bud by the immune response, not least by its T cells, which detect telltale molecular markers—or antigens—on cancer cells and destroy them before they grow into tumors. Cancer cells, for their part, evolve constantly to evade such assassination. Those that succeed become full-blown malignancies. Yet, given the right sort of help, the immune system can destroy even these entrenched tumors. http://medicalxpress.com/news/2012-10-mouse-exposes-cell-melanoma.html Cancer Wed, 24 Oct 2012 12:00:01 EST news270298157 A group of molecular markers have been identified that can help clinicians determine which patients with low-grade oral premalignant lesions are at high risk for progression to oral cancer, according to data from the Oral Cancer Prediction Longitudinal Study published in Cancer Prevention Research, a journal of the American Association for Cancer Research. http://medicalxpress.com/news/2012-08-markers-oral-lesions-cancer.html Cancer Tue, 21 Aug 2012 13:28:03 EST news264774416 (Medical Xpress) -- A new study by TCD researchers investigates drug-resistant ovarian cancer cells. The findings which have been recently published in the international publication, PLoS One will increase understanding of molecular markers in drug-resistant ovarian cancer with a view to improving clinical treatment. http://medicalxpress.com/news/2012-08-drug-resistant-ovarian-cancer-clinical.html Cancer Thu, 09 Aug 2012 08:47:52 EST news263720848 Researchers at The University of Nottingham have identified three sets of genetic markers that could potentially pave the way for new diagnostic tools for a deadly type of brain tumour that mainly targets children. http://medicalxpress.com/news/2012-06-genetic-markers-brain-tumor-treatments.html Cancer Fri, 15 Jun 2012 11:06:09 EST news258977156 These days, most of us don't head to the doctor until we are already ill. What if you could see disease approaching just as it starts to head your way? A study in a special March 16th issue of Cell focused on human biology shows that this futuristic notion is already in reach. Scientists have combined a complete personal genome sequence with analyses of disease risks and an array of dynamic molecular measures, capturing important changes in the way the human body works. The study is the first to apply "integrative Personal Omics Profiling" (iPOP for short) to observe healthy and diseased states, the researchers say. http://medicalxpress.com/news/2012-03-disease-unprecedented.html Genetics Thu, 15 Mar 2012 12:02:29 EST news251031731 Molecular markers found in cancer cells that have spread from a primary tumor to a limited number of distant sites can help physicians predict which patients with metastatic cancer will benefit from aggressive, targeted radiation therapy. http://medicalxpress.com/news/2011-12-molecular-markers-cancer-treatment.html Cancer Tue, 13 Dec 2011 17:00:05 EST news243016189 A new strategy that takes advantage of ovarian cancer's reliance on folate appears to give relapse patients extra months of life with few side effects, researchers say. http://medicalxpress.com/news/2011-10-folate-receptors-front-door-ovarian.html Cancer Fri, 28 Oct 2011 11:11:47 EST news239019097 New guidelines that provide an easy-to-use checklist for the accurate and ethical reporting of epidemiological studies involving molecular markers have been proposed by a group of international researchers and are published in this week's PLoS Medicine. http://medicalxpress.com/news/2011-10-guidelines-epidemiological-involve-molecular-markers.html Cancer Tue, 25 Oct 2011 17:42:58 EST news238783364