http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. A clinical trial has shown that patients, and their physicians, are eager to jump into next-era cancer care—analysis of an individual's tumor to find and target genetic mutations that drive the cancer. Results of the study, CUSTOM, are being presented at the 2013 annual meeting of the American Society of Clinical Oncology years before investigators thought they would be ready. http://medicalxpress.com/news/2013-05-prospective-trial-molecular-profiling-tailoring.html Cancer Wed, 15 May 2013 18:00:02 EST news287856906 Exosomes are small, virus-like particles that can transport genetic material and signal substances between cells. Researchers at Lund University, Sweden, have made new findings about exosomes released from aggressive brain tumors, gliomas. These exosomes are shown to have an important function in brain tumor development, and could be utilized as biomarkers to assess tumor aggressiveness through a blood test. http://medicalxpress.com/news/2013-04-virus-like-particles-vital-clues-brain.html Medical research Wed, 17 Apr 2013 10:18:15 EST news285412653 Head and neck squamous cell carcinoma (HNSCC) is the seventh most common form of cancer in the United States, but other than an association with the human papillomavirus, no validated molecular profile of the disease has been established. By analyzing data from DNA microarrays, a UNC-led team has completed a study that confirms the presence of four molecular classes of the disease and extends previous results by suggesting that there may be an underlying connection between the molecular classes and observed genomic events, some of which affect known cancer genes. The clinical relevance of the classes and certain genomic events was demonstrated, thus paving the way for further studies and possible targeted therapies. http://medicalxpress.com/news/2013-02-tudy-documents-neck-cancer-molecular.html Cancer Fri, 22 Feb 2013 18:09:29 EST news280778962 Cancer therapies targeting specific molecular subtypes of the disease allow physicians to tailor treatment to a patient's individual molecular profile. But scientists are finding that in many types of cancer the molecular subtypes are more varied than previously thought and contain further genetic alterations that can affect a patient's response to therapy. http://medicalxpress.com/news/2012-05-molecular-subtypes-genetic-response-lung.html Cancer Fri, 11 May 2012 15:12:55 EST news255967873 A new patent has been issued to Moffitt Cancer Center for a computerized system that efficiently selects the right patient for the right clinical trial. The newly patented system matches the registered patient's own molecular profile – warehoused in a database of thousands of patient-donated biological tissue or tumor samples – to the molecular design of the drug aimed at targeting their disease at the molecular level, and does it quickly. The system promises to accelerate clinical trials and help shorten the time that it takes to get critically needed new drugs into the market. http://medicalxpress.com/news/2012-02-moffitt-cancer-center-patent-trials.html Cancer Tue, 14 Feb 2012 11:40:33 EST news248442021 Scientists at the University of California, San Francisco (UCSF) have identified nearly 200 genes in the healthy prostate tissue of men with low-grade prostate cancer that may help explain how physical activity improves survival from the disease. http://medicalxpress.com/news/2012-02-vigorous-linked-gene-prostate.html Cancer Wed, 01 Feb 2012 16:00:01 EST news247333376