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The culmination of three decades of research in Cambridge has resulted in the exciting prospect of a new transformational treatment for multiple sclerosis. http://medicalxpress.com/news/2011-11-treatment-multiple-sclerosis-cambridge-university.html Medical research Tue, 15 Nov 2011 11:43:37 EST news240579807 Patients unable to control their cholesterol levels with medications may someday be able to lower their "bad" cholesterol with a shot, according to research presented at the American Heart Association's Scientific Sessions 2011. http://medicalxpress.com/news/2011-11-lowers-cholesterol-preliminary-human-trial.html Cardiology Mon, 14 Nov 2011 09:29:33 EST news240485364 A new potential target to slow breast cancer tumor progression and metastasis has been identified by a team of researchers led by Dr. Richard Kremer from the Research Institute of the McGill University Health Centre (RI-MUHC). Complications in breast cancer patients are commonly caused by the spread of the disease through metastasis to other parts of the body, most often to the bones and lungs. These findings, published this week in the Journal of Clinical Investigation (JCI), suggest that a specific protein plays a key role in the progression of the disease outside of the initial tumor area. http://medicalxpress.com/news/2011-11-breast-cancer_1.html Cancer Thu, 10 Nov 2011 12:42:00 EST news240151312 A human monoclonal antibody developed by MassBiologics of the University of Massachusetts Medical School (UMMS) given to patients with chronic hepatitis C virus (HCV) infection undergoing liver transplantation significantly suppressed the virus for at least a week after transplant and delayed the time to viral rebound. Results from a randomized, double-blind, placebo-controlled, phase 2 study were presented this week at The Liver Meeting, the annual meeting of the American Association for the Study of Liver Diseases, in San Francisco. http://medicalxpress.com/news/2011-11-experimental-drug-suppresses-rebound-hepatitis.html Diseases, Conditions, Syndromes Mon, 07 Nov 2011 16:02:35 EST news239904145 Virginia Commonwealth University School of Medicine researchers have discovered that the infiltration of white blood cells into an expectant mother's blood vessels may explain high blood pressure in pregnancy. http://medicalxpress.com/news/2011-10-high-blood-pressure-pregnancy.html Obstetrics & gynaecology Mon, 31 Oct 2011 14:38:56 EST news239290730 A collaborative research team from Boston University School of Medicine (BUSM), the Uniformed Services University of the Health Sciences (USU), the University of Texas Medical Branch (UTMB) and Galveston National Laboratory (GNL), the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Rocky Mountain Laboratories (RML), and the National Cancer Institute (NCI), reports a breakthrough in the development of an effective therapy against a deadly virus, Hendra virus. The results of their research appear in Science Translational Medicine today. http://medicalxpress.com/news/2011-10-major-advance-treatment-hendra-virus.html Medical research Wed, 19 Oct 2011 14:00:02 EST news238247944 Biological agents used to treat rheumatoid arthritis seem to be associated with an increased risk of skin cancer, indicates a systematic review of published research in the Annals of the Rheumatic Diseases. http://medicalxpress.com/news/2011-09-biological-agents-rheumatoid-arthritis-skin.html Cancer Thu, 08 Sep 2011 05:17:02 EST news234677807 A paper published today in the scientific research journal Science, describes a novel, proprietary monoclonal antibody (FI6) discovered in a collaboration between Humabs BioMed SA, the Institute for Research in Biomedicine ("IRB") and the UK Medical Research Council (MRC). FI6 is the first neutralizing antibody that targets all 16 hemagglutinin subtypes of influenza A and represents an important development in the treatment of severe cases of flu, and in finding a universal flu vaccine. The paper also discusses Humabs' high throughput method of selecting rare antibodies from cultured plasma cells. http://medicalxpress.com/news/2011-07-humabs-antibody-neutralize-group-influenza.html Medical research Thu, 28 Jul 2011 14:05:29 EST news231080717 UK regulators have approved Europe's first clinical trial of a monoclonal antibody produced from genetically modified plants. This landmark decision sets the stage for the testing, in humans, of an anti-HIV product made from genetically modified tobacco plants. It will open the door for trials of additional plant-derived medicines treating a range of diseases. http://medicalxpress.com/news/2011-07-clinical-medicines-genetically.html Other Thu, 21 Jul 2011 10:29:35 EST news230462955 University of Queensland researchers have produced batches of a monoclonal antibody, which may offer hope as a potential therapeutic for Hendra virus infection in humans. http://medicalxpress.com/news/2011-07-hendra-virus-facts.html Diseases, Conditions, Syndromes Tue, 12 Jul 2011 10:58:43 EST news229687106 Memorial Sloan-Kettering Cancer Center physician-scientists report that women with small, node-negative, HER2-positive breast cancer may obtain a significant benefit from adjuvant chemotherapy with trastuzumab (Herceptin), a drug previously shown to improve outcomes in advanced cancer and prevent the return of cancer in women diagnosed with higher-risk, early-stage, HER2-positive breast cancer. This study appears online in the journal Cancer, and will be published in a future print edition. http://medicalxpress.com/news/2011-06-breast-cancer-treatment-benefit-women.html Cancer Tue, 28 Jun 2011 12:39:09 EST news228483532 A new treatment for colon cancer that combines a chemotherapy agent approved to treat breast cancer and a cancer-fighting antibody is ready for clinical trials, according to Penn State College of Medicine researchers. http://medicalxpress.com/news/2011-06-breast-cancer-drug-colon-cells.html Cancer Wed, 08 Jun 2011 14:00:01 EST news226756743 Researchers are halting kidney cancer with a novel form of radioimmunotherapy that zeroes in on antigens associated with renal cell carcinoma. Patients with progressive kidney cancer receiving up to three doses of the therapy show dramatic slowing of cancer growth and stabilization of their disease. http://medicalxpress.com/news/2011-06-cancer-seeking-smart-kidney-cancer-cells.html Cancer Mon, 06 Jun 2011 13:40:05 EST news226584282 (Medical Xpress) -- A duo of drugs, each targeting a prime survival strategy of tumors, can be safely administered and are potentially more effective than either drug alone for advanced, inoperable melanomas, according to a phase 1 clinical trial led by Dana-Farber Cancer Institute investigators. http://medicalxpress.com/news/2011-06-combination-antibody-therapy-metastatic-melanoma.html Cancer Sat, 04 Jun 2011 01:57:41 EST news226371396 In the online version of the New England Journal of Medicine, physicians and scientists in Heidelberg, Montreal, and Paris reported on the successful treatment of three young children who were suffering from a severe hemolytic-uremic syndrome (HUS) after an infection with enterohemorrhagic Escherichia coli (EHEC). The infections occurred in 2010. EHEC are the bacteria that cause the current wave of infections that have already claimed ten lives in Germany. The number of suspected and confirmed cases of EHEC has now reached 700. http://medicalxpress.com/news/2011-05-antibodies-successful-treatment-hemolytic-uremic-syndrome.html Diseases, Conditions, Syndromes Tue, 31 May 2011 11:04:57 EST news226058675 An antibody packaged with a potent chemotherapy drug to selectively destroy acute lymphoblastic leukemia (ALL) cells eradicated or greatly reduced the disease for 61 percent of 46 patients in a phase II study. It will be presented at the 47th annual meeting of the American Society of Clinical Oncology in Chicago June 3-7. http://medicalxpress.com/news/2011-05-antibody-guided-drug-acute-lymphoblastic-leukemia.html Cancer Mon, 23 May 2011 16:02:14 EST news225385321