https://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. More than half of patients in a Phase III clinical trial who received a limited course of the experimental monoclonal antibody ianalumab for primary immune thrombocytopenia (ITP), an autoimmune disorder that can cause life-threatening bleeding, were able to maintain safe platelet counts without serious bleeding episodes for at least one year. https://medicalxpress.com/news/2025-12-experimental-antibody-enables-platelet-stability.html Tue, 09 Dec 2025 07:30:01 EST news684482907 A new study led by University of Toronto researchers has shown that immune cells in the gut follow an atypical pathway to produce antibodies that provide long-term protection against viruses. https://medicalxpress.com/news/2025-11-gut-immunity-viral-infections.html Mon, 17 Nov 2025 16:10:01 EST news682618033 Equids, members of the horse family including horses, donkeys and zebras, share curious features called chestnuts. Found on every horse, they appear as toughened growths on their limbs, and can be clipped back if they grow too large. Anyone following the charming and rugged farrier Sam Wolfenden on TikTok will have seen his expert chestnut clipping. https://medicalxpress.com/news/2025-11-humans-horns.html Mon, 03 Nov 2025 20:30:01 EST news681392635 Raw milk cheese products contained infectious avian influenza virus when made with contaminated raw milk, creating potential health risks for consumers, according to a new study. https://medicalxpress.com/news/2025-10-bird-flu-persists-raw-cheese.html Wed, 08 Oct 2025 14:15:04 EDT news679151701 A man in his 50s has died from lyssavirus in New South Wales after being bitten by a bat several months ago. https://medicalxpress.com/news/2025-07-lyssavirus-rare-deadly.html Fri, 04 Jul 2025 05:54:05 EDT news670827241 Irritable bowel syndrome, chronic itching, asthma and migraine are in many cases hard-to-treat conditions. They have in common that they are triggered by an excessive immune response—which in severe cases can be life-threatening. https://medicalxpress.com/news/2025-04-bioactive-compound-blocks-key-immune.html Thu, 24 Apr 2025 09:22:04 EDT news664705322 You've probably heard "Don't go outside in the winter with your hair wet or without a coat; you'll catch a cold." https://medicalxpress.com/news/2024-12-winter-vulnerable-colds-health-nurse.html Thu, 12 Dec 2024 10:37:07 EST news653222215 Researchers have identified the skin cells responsible for orchestrating cases of two of the most life-threatening drug reactions. Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) cause the skin and mucous membranes to blister and detach, and carry an average mortality rate of 20%. https://medicalxpress.com/news/2024-10-assassin-cells-play-key-role.html Mon, 28 Oct 2024 08:59:04 EDT news649324741 During the COVID pandemic, many of us received multiple mRNA vaccines. New work by researchers at the VIB-UGent Center for Inflammation Research, Ghent University, and University Hospital Ghent, among others, has found that such repeated vaccinations lead to the presence of mucosal antibodies, for example, inside the nose. Their work appears in Science Translational Medicine. https://medicalxpress.com/news/2024-10-covid-vaccinations-mucosal-immunity-virus.html Wed, 23 Oct 2024 15:07:03 EDT news648914821 If button cells are swallowed, they may get stuck in the esophagus. This can sometimes lead to severe damage to the mucous membranes. "Over the past 10 years, clinics and poison centers have reported several hundred cases to the BfR in which button cells have been swallowed," reports BfR President Professor Hensel. https://medicalxpress.com/news/2024-10-button-cells-health-small-children.html Tue, 01 Oct 2024 12:02:04 EDT news647002921 A case report published in the New England Journal of Medicine describes a previously unidentified orthonairovirus, dubbed Wetland virus (WELV), in a man bitten by a tick at a wetland park in Inner Mongolia, China, in 2019. https://medicalxpress.com/news/2024-09-scientists-orthonairovirus-bitten-china.html Tue, 10 Sep 2024 10:56:03 EDT news645184561 Varicella zoster virus (VZV) can cause chickenpox, as well as shingles and severe complications. When one comes into contact with VZV for the first time, the virus enters the body through the airways, reaching the mucous membranes in the nasopharynx and adjacent lymphatic tissues, from where VZV infects T lymphocytes. https://medicalxpress.com/news/2024-07-seemingly-paradoxical-strategy-varicella-zoster.html Fri, 12 Jul 2024 08:54:03 EDT news639993242 A drug approved to treat certain autoimmune diseases and cancers successfully alleviated symptoms of a rare genetic syndrome called autoimmune polyendocrine syndrome type 1 (APS-1). Researchers identified the treatment based on their discovery that the syndrome is linked to elevated levels of interferon-gamma (IFN-gamma), a protein involved in immune system responses, providing new insights into the role of IFN-gamma in autoimmunity. https://medicalxpress.com/news/2024-05-drug-treatment-rare-genetic-disorder.html Thu, 30 May 2024 11:39:03 EDT news636287941 Dengue, caused by the virus transmitted by the bite of the female Aedes aegypti mosquito and, to a lesser extent, the Aedes albopictus mosquito, is an acute illness characterized mainly by high fever, body aches, and redness of the skin. https://medicalxpress.com/news/2024-03-brazilian-dose-dengue-vaccine-tide.html Sat, 16 Mar 2024 10:10:01 EDT news629636929 A research perspective was recently published in Oncoscience, titled "Squamous cell carcinoma of the oral cavity—follow up treatment and distant metastatic behavior." https://medicalxpress.com/news/2023-12-squamous-cell-carcinoma-oral-cavity.html Wed, 27 Dec 2023 14:50:13 EST news622911008 A team of researchers investigating the transmission of HIV have discovered that HIV antibodies provide sterilizing immunity by inhibiting the infection of the first cell. The research is published in the journal Cell Reports Medicine. https://medicalxpress.com/news/2023-10-antibodies-infection-hiv.html Thu, 12 Oct 2023 10:29:03 EDT news616325341 Picking your nose is linked to an increased risk of COVID, according to a study out today. https://medicalxpress.com/news/2023-08-nose-covid.html Thu, 03 Aug 2023 11:26:49 EDT news610280803 Sir Elton John set a record at this year's Glastonbury, becoming the most-watched headliner in the festival's history, with more than 7 million people tuning in live to the BBC to watch his last ever UK performance. https://medicalxpress.com/news/2023-06-voices-older.html Fri, 30 Jun 2023 11:59:42 EDT news607345179 Our noses perform important functions every day of our lives, but we often only notice when disease changes how they work. https://medicalxpress.com/news/2023-06-snot-green-deep-sinuses-fascinating.html Wed, 07 Jun 2023 13:28:04 EDT news605363282 Throughout a woman's reproductive life, the endometrium, the mucous membrane lining the uterus, goes through cyclical remodeling. It thickens during the menstrual cycle in preparation for embryo implantation, and it is shed during menstruation when there is no fertilization. https://medicalxpress.com/news/2023-04-protein-beclin-shown-major-player.html Mon, 10 Apr 2023 11:00:10 EDT news600336293 In order for migraine medication to be effective, it is vital that the active substance is released into the bloodstream immediately. The pills currently on the market today pass through the body's metabolism which means the effectiveness is lessened and there is a delay to the relief. https://medicalxpress.com/news/2023-01-optimal-migraine-relief.html Thu, 26 Jan 2023 13:50:03 EST news593963401 Increased levels of the antibody immunoglobulin A (IgA) are correlated with the manifestation of several diseases as well as African ancestry, according to findings published in Nature Communications. The findings provide new insights into the genetic regulation of IgA levels and its potential role in human disease. https://medicalxpress.com/news/2023-01-exploring-genetic-immunoglobulin.html Thu, 05 Jan 2023 08:59:25 EST news592131561 Less known to the general public, mucosal vaccination via the mucus membranes could provide robust protection against SARS-CoV-2 infections. Immune cells in the nose and lungs are considered better prepared to encounter and block the virus that causes COVID-19. https://medicalxpress.com/news/2022-12-covid-respiratory-mucosal-vaccine-effective.html Fri, 16 Dec 2022 13:32:05 EST news590419923 Up to 15% of women of reproductive age in the United States suffer from endometriosis, a condition characterized by pelvic pain, menstrual cramps and infertility. Endometriosis develops when tissue like the lining on the inside of the womb grows outside of the uterus. This growth may swell and bleed, leading to pain and other symptoms. https://medicalxpress.com/news/2022-12-exploring-potential-treatment-endometriosis.html Tue, 13 Dec 2022 16:46:02 EST news590172361 The presence of food-specific IgA antibodies in the gut does not prevent peanut or egg allergies from developing in children, according to a Northwestern Medicine study published in Science Translational Medicine. https://medicalxpress.com/news/2022-12-re-examining-antibodies-role-childhood-allergies.html Fri, 02 Dec 2022 13:34:21 EST news589210455 A team of researchers at Duke University has developed a vaccine against uropathogenic E. coli (UPEC), the type of bacteria that cause urinary tract infections (UTIs) in humans. In their paper published in the journal Science Advances, the group describes how they made their vaccine and its performance when tested in mice and rabbits. https://medicalxpress.com/news/2022-11-vaccine-bacteria-utis.html Fri, 25 Nov 2022 13:40:01 EST news588603873 Inflammatory bowel disease is a risk factor for giving birth preterm even when in apparent disease remission, a University of Gothenburg study shows. If corroborated, the results may eventually affect recommendations for women with ulcerative colitis who tries to conceive. https://medicalxpress.com/news/2022-11-exploring-adverse-pregnancy-outcomes-women.html Mon, 07 Nov 2022 13:35:45 EST news587050544 Tokyo Medical and Dental University (TMDU) research team announced on July 7 that it has succeeded in the world's first clinical transplantation of a "mini organ" (also called an organoid) into a patient with ulcerative colitis (UC). UC causes inflammation and ulcers (sores) in your digestive tract. It can be debilitating and can sometimes lead to life-threatening complications. UC belongs to a group of conditions called Inflammatory Bowel Disease (IBD). The number of patients is increasing in Japan, and worldwide is estimated to be about 5,000,000. The common treatment is to suppress inflammation with drugs, but in severe cases, the entire colon may be removed. https://medicalxpress.com/news/2022-08-world-mini-patient-ulcerative-colitis.html Mon, 22 Aug 2022 14:04:37 EDT news580395875 A new mouse model identified by virologists from the University of Pittsburgh might revolutionize development of therapies targeting brain inflammation caused by Rift Valley Fever virus (RVFV). https://medicalxpress.com/news/2022-07-brain-attacking-viruses.html Thu, 14 Jul 2022 14:00:12 EDT news576997976 During the currently evolving outbreak of monkeypox cases worldwide, 31 cases have been confirmed in the Netherlands up to 31 May 2022. Efforts to stop the spread of infection focus on active case finding, contact tracing of close contacts and their isolation or quarantine. Related recommendations from public health bodies on the need for active monitoring and isolation for a minimum of 21 days after the last day of exposure are based on the known monkeypox incubation period (up to 21 days). https://medicalxpress.com/news/2022-06-incubation-period-monkeypox-netherlands.html Thu, 16 Jun 2022 13:24:02 EDT news574604641